Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NMAA_RS10040 Genome accession   NC_017512
Coordinates   1911202..1912062 (+) Length   286 a.a.
NCBI ID   WP_002220276.1    Uniprot ID   -
Organism   Neisseria meningitidis WUE 2594     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1906202..1917062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMAA_RS10025 (NMAA_1654) dapD 1906908..1907729 (-) 822 WP_002216408.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  NMAA_RS10030 (NMAA_1655) pgi 1907896..1909539 (-) 1644 WP_002245857.1 glucose-6-phosphate isomerase -
  NMAA_RS10035 (NMAA_1656) pilG 1909896..1911128 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  NMAA_RS10040 (NMAA_1657) pilD 1911202..1912062 (+) 861 WP_002220276.1 prepilin peptidase Machinery gene
  NMAA_RS10045 (NMAA_1658) coaE 1912064..1912696 (+) 633 WP_002245856.1 dephospho-CoA kinase -
  NMAA_RS10050 (NMAA_1659) - 1912689..1912898 (+) 210 WP_002212333.1 DNA gyrase inhibitor YacG -
  NMAA_RS10055 (NMAA_1660) pilF 1912983..1914659 (-) 1677 WP_002245855.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NMAA_RS10065 (NMAA_1661) - 1915101..1915547 (-) 447 WP_002233503.1 DUF441 domain-containing protein -
  NMAA_RS10070 (NMAA_1662) ispB 1915552..1916526 (-) 975 WP_002216396.1 octaprenyl diphosphate synthase -
  NMAA_RS10075 (NMAA_1663) rplU 1916750..1917058 (+) 309 WP_002216394.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31359.40 Da        Isoelectric Point: 8.2213

>NTDB_id=47878 NMAA_RS10040 WP_002220276.1 1911202..1912062(+) (pilD) [Neisseria meningitidis WUE 2594]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=47878 NMAA_RS10040 WP_002220276.1 1911202..1912062(+) (pilD) [Neisseria meningitidis WUE 2594]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACCTTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

96.14

99.65

0.958
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment