Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NMAA_RS10200 Genome accession   NC_017512
Coordinates   1938148..1938612 (-) Length   154 a.a.
NCBI ID   WP_010981060.1    Uniprot ID   -
Organism   Neisseria meningitidis WUE 2594     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1938148..1948666 1938148..1938612 within 0
IS/Tn 1936805..1937458 1938148..1938612 flank 690


Gene organization within MGE regions


Location: 1936805..1948666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMAA_RS10190 (NMAA_1681) - 1936805..1937458 (-) 654 WP_002245850.1 IS1595 family transposase -
  NMAA_RS15475 - 1937578..1938036 (-) 459 WP_002234522.1 hypothetical protein -
  NMAA_RS10200 (NMAA_1682) comE 1938148..1938612 (-) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  NMAA_RS10235 (NMAA_1683) - 1944413..1945219 (-) 807 WP_002245849.1 inner membrane protein YpjD -
  NMAA_RS10240 (NMAA_1684) ffh 1945440..1946810 (+) 1371 WP_002245848.1 signal recognition particle protein -
  NMAA_RS10245 (NMAA_1685) dsbA2 1947141..1947836 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMAA_RS10250 (NMAA_1686) - 1948007..1948666 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16529.75 Da        Isoelectric Point: 10.6993

>NTDB_id=47880 NMAA_RS10200 WP_010981060.1 1938148..1938612(-) (comE) [Neisseria meningitidis WUE 2594]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=47880 NMAA_RS10200 WP_010981060.1 1938148..1938612(-) (comE) [Neisseria meningitidis WUE 2594]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment