Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | HX107_RS06710 | Genome accession | NZ_CP058563 |
| Coordinates | 1414648..1414923 (+) | Length | 91 a.a. |
| NCBI ID | WP_002356991.1 | Uniprot ID | A0A1B4XPV0 |
| Organism | Enterococcus faecalis strain YMC_2019_05_SA7 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1414947..1460401 | 1414648..1414923 | flank | 24 |
Gene organization within MGE regions
Location: 1414648..1460401
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HX107_RS06710 (HX107_06680) | comGC/cglC | 1414648..1414923 (+) | 276 | WP_002356991.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| HX107_RS06715 (HX107_06685) | comGD | 1414920..1415363 (+) | 444 | WP_129992406.1 | competence type IV pilus minor pilin ComGD | - |
| HX107_RS06720 (HX107_06690) | - | 1415391..1416539 (-) | 1149 | WP_105194837.1 | tyrosine-type recombinase/integrase | - |
| HX107_RS06725 (HX107_06695) | - | 1416636..1417364 (-) | 729 | WP_033918699.1 | ion transporter | - |
| HX107_RS06730 (HX107_06700) | - | 1417398..1417742 (-) | 345 | WP_105194759.1 | ImmA/IrrE family metallo-endopeptidase | - |
| HX107_RS06735 (HX107_06705) | - | 1417760..1418092 (-) | 333 | WP_002364355.1 | helix-turn-helix domain-containing protein | - |
| HX107_RS06740 (HX107_06710) | - | 1418404..1418580 (+) | 177 | WP_002364354.1 | helix-turn-helix domain-containing protein | - |
| HX107_RS06745 (HX107_06715) | - | 1418591..1418902 (+) | 312 | WP_105194760.1 | hypothetical protein | - |
| HX107_RS06750 (HX107_06720) | - | 1418909..1419088 (+) | 180 | WP_002395800.1 | hypothetical protein | - |
| HX107_RS06755 | - | 1419089..1419505 (+) | 417 | WP_226088780.1 | hypothetical protein | - |
| HX107_RS06760 (HX107_06730) | - | 1419720..1419920 (+) | 201 | WP_105194762.1 | hypothetical protein | - |
| HX107_RS06765 (HX107_06735) | - | 1419917..1420210 (+) | 294 | WP_010826715.1 | VRR-NUC domain-containing protein | - |
| HX107_RS06770 (HX107_06740) | - | 1420200..1421396 (+) | 1197 | WP_016626781.1 | DEAD/DEAH box helicase | - |
| HX107_RS06775 (HX107_06745) | - | 1421398..1421640 (+) | 243 | WP_010826713.1 | hypothetical protein | - |
| HX107_RS06780 (HX107_06750) | - | 1421653..1422564 (+) | 912 | WP_105194763.1 | YqaJ viral recombinase family protein | - |
| HX107_RS06785 (HX107_06755) | - | 1422633..1422776 (+) | 144 | WP_226088781.1 | hypothetical protein | - |
| HX107_RS06790 (HX107_06760) | - | 1422773..1422973 (+) | 201 | WP_057086713.1 | hypothetical protein | - |
| HX107_RS06795 (HX107_06765) | - | 1422976..1423896 (+) | 921 | WP_105194764.1 | AAA family ATPase | - |
| HX107_RS06800 (HX107_06770) | - | 1423947..1424459 (+) | 513 | WP_016626786.1 | hypothetical protein | - |
| HX107_RS06805 (HX107_06775) | - | 1424482..1426044 (+) | 1563 | Protein_1310 | hypothetical protein | - |
| HX107_RS06810 (HX107_06780) | - | 1426041..1426793 (-) | 753 | WP_162301521.1 | DUF4145 domain-containing protein | - |
| HX107_RS06815 (HX107_06785) | - | 1426869..1428722 (+) | 1854 | WP_410500858.1 | phage/plasmid primase, P4 family | - |
| HX107_RS06820 (HX107_06790) | - | 1429028..1429444 (+) | 417 | WP_010826705.1 | sigma-70 family RNA polymerase sigma factor | - |
| HX107_RS06825 (HX107_06795) | - | 1429576..1429977 (+) | 402 | WP_104874806.1 | hypothetical protein | - |
| HX107_RS06830 (HX107_06800) | - | 1429977..1430345 (+) | 369 | WP_002393035.1 | HNH endonuclease | - |
| HX107_RS06835 (HX107_06805) | - | 1430458..1430910 (+) | 453 | WP_064687382.1 | P27 family phage terminase small subunit | - |
| HX107_RS06840 (HX107_06810) | - | 1430907..1432634 (+) | 1728 | WP_105194769.1 | terminase large subunit | - |
| HX107_RS06845 (HX107_06815) | - | 1432653..1433864 (+) | 1212 | WP_029736326.1 | phage portal protein | - |
| HX107_RS06850 (HX107_06820) | - | 1433851..1434423 (+) | 573 | WP_002393031.1 | HK97 family phage prohead protease | - |
| HX107_RS06855 (HX107_06825) | - | 1434435..1435796 (+) | 1362 | WP_105194770.1 | phage major capsid protein | - |
| HX107_RS06860 (HX107_06830) | - | 1435799..1436080 (+) | 282 | WP_002395304.1 | phage gp6-like head-tail connector protein | - |
| HX107_RS06865 (HX107_06835) | - | 1436058..1436384 (+) | 327 | WP_002373974.1 | phage head closure protein | - |
| HX107_RS06870 (HX107_06840) | - | 1436374..1436712 (+) | 339 | WP_002398474.1 | hypothetical protein | - |
| HX107_RS06875 (HX107_06845) | - | 1436702..1437064 (+) | 363 | WP_105194771.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| HX107_RS06880 (HX107_06850) | - | 1437061..1437708 (+) | 648 | WP_105194772.1 | phage tail protein | - |
| HX107_RS06885 (HX107_06855) | - | 1437708..1438163 (+) | 456 | WP_410500622.1 | hypothetical protein | - |
| HX107_RS06890 (HX107_06860) | - | 1438355..1440652 (+) | 2298 | WP_129992407.1 | phage tail tape measure protein | - |
| HX107_RS06895 (HX107_06865) | - | 1440655..1441359 (+) | 705 | WP_010826698.1 | hypothetical protein | - |
| HX107_RS06900 (HX107_06870) | - | 1441356..1444193 (+) | 2838 | WP_105194774.1 | phage tail tip lysozyme | - |
| HX107_RS06905 (HX107_06875) | - | 1444212..1445126 (+) | 915 | WP_129992378.1 | phage baseplate upper protein | - |
| HX107_RS06910 (HX107_06880) | - | 1445119..1445715 (+) | 597 | WP_129992379.1 | hypothetical protein | - |
| HX107_RS06915 (HX107_06885) | - | 1445712..1445999 (+) | 288 | WP_129992380.1 | collagen-like protein | - |
| HX107_RS06920 (HX107_06890) | - | 1445999..1447216 (+) | 1218 | WP_129992381.1 | glycerophosphodiester phosphodiesterase | - |
| HX107_RS06925 (HX107_06895) | - | 1447224..1447448 (+) | 225 | WP_370689693.1 | BhlA/UviB family holin-like peptide | - |
| HX107_RS06930 (HX107_06900) | - | 1447490..1448575 (+) | 1086 | WP_105194863.1 | SH3 domain-containing protein | - |
| HX107_RS06935 (HX107_06905) | - | 1448726..1449097 (+) | 372 | WP_172351944.1 | type II secretion system protein | - |
| HX107_RS06940 (HX107_06910) | comGF | 1449087..1449521 (+) | 435 | WP_002357060.1 | competence type IV pilus minor pilin ComGF | - |
| HX107_RS06945 (HX107_06915) | comGG | 1449521..1449874 (+) | 354 | WP_010710571.1 | competence type IV pilus minor pilin ComGG | - |
| HX107_RS06950 (HX107_06920) | - | 1450003..1451010 (+) | 1008 | WP_002357063.1 | class I SAM-dependent methyltransferase | - |
| HX107_RS06955 (HX107_06925) | - | 1451035..1452222 (+) | 1188 | WP_002357064.1 | acetate/propionate family kinase | - |
| HX107_RS06960 (HX107_06930) | - | 1452334..1452807 (-) | 474 | WP_410500625.1 | universal stress protein | - |
| HX107_RS06965 (HX107_06935) | - | 1453123..1453455 (-) | 333 | WP_002357068.1 | hypothetical protein | - |
| HX107_RS06975 (HX107_06945) | - | 1453729..1455006 (-) | 1278 | WP_002360030.1 | replication-associated recombination protein A | - |
| HX107_RS06980 (HX107_06950) | - | 1455135..1455813 (+) | 679 | Protein_1344 | DNA-3-methyladenine glycosylase | - |
| HX107_RS06985 (HX107_06955) | - | 1455770..1456261 (+) | 492 | WP_410500627.1 | DUF3013 family protein | - |
| HX107_RS06990 (HX107_06960) | prmA | 1456272..1457219 (+) | 948 | WP_078122738.1 | 50S ribosomal protein L11 methyltransferase | - |
| HX107_RS06995 (HX107_06965) | - | 1457221..1457973 (+) | 753 | WP_002378439.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
| HX107_RS07000 (HX107_06970) | - | 1458188..1460401 (+) | 2214 | WP_002357079.1 | RelA/SpoT family protein | - |
Sequence
Protein
Download Length: 91 a.a. Molecular weight: 10464.41 Da Isoelectric Point: 9.3192
>NTDB_id=464329 HX107_RS06710 WP_002356991.1 1414648..1414923(+) (comGC/cglC) [Enterococcus faecalis strain YMC_2019_05_SA7]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ
Nucleotide
Download Length: 276 bp
>NTDB_id=464329 HX107_RS06710 WP_002356991.1 1414648..1414923(+) (comGC/cglC) [Enterococcus faecalis strain YMC_2019_05_SA7]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus pneumoniae Rx1 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae D39 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae R6 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus mitis NCTC 12261 |
61.905 |
92.308 |
0.571 |
| comGC/cglC | Streptococcus mitis SK321 |
61.176 |
93.407 |
0.571 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
58.14 |
94.505 |
0.549 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
56.322 |
95.604 |
0.538 |
| comYC | Streptococcus suis isolate S10 |
52.326 |
94.505 |
0.495 |
| comYC | Streptococcus mutans UA159 |
57.692 |
85.714 |
0.495 |
| comYC | Streptococcus mutans UA140 |
57.692 |
85.714 |
0.495 |
| comGC | Latilactobacillus sakei subsp. sakei 23K |
46.154 |
100 |
0.462 |
| comGC | Staphylococcus aureus MW2 |
46.835 |
86.813 |
0.407 |
| comGC | Staphylococcus aureus N315 |
46.835 |
86.813 |
0.407 |
| comGC | Bacillus subtilis subsp. subtilis str. 168 |
48.649 |
81.319 |
0.396 |