Detailed information NTG0449593

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STT55_RS07915
• Genome accession: NZ_CP065502
• Coordinates: 1516324..1517109 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain ST55
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1511324..1522109

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT55_RS07880 (STT55_07815)	gatC	1511390..1511692 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
STT55_RS07885 (STT55_07820)	-	1511832..1512086 (-)	255	WP_011226449.1	glycosyl transferase	-
STT55_RS07890 (STT55_07825)	-	1512099..1512296 (-)	198	WP_231108739.1	glycosyltransferase	-
STT55_RS07895 (STT55_07830)	-	1512624..1514065 (-)	1442	Protein_1502	6-phospho-beta-glucosidase	-
STT55_RS07900 (STT55_07835)	msrA	1514218..1514727 (-)	510	WP_002946589.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STT55_RS07905 (STT55_07840)	-	1514739..1515587 (-)	849	WP_022096458.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STT55_RS07910 (STT55_07845)	-	1515710..1516261 (-)	552	WP_173940634.1	isochorismatase family cysteine hydrolase	-
STT55_RS07915 (STT55_07850)	codY	1516324..1517109 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STT55_RS07920 (STT55_07855)	-	1517369..1518583 (-)	1215	WP_011226456.1	pyridoxal phosphate-dependent aminotransferase	-
STT55_RS07925 (STT55_07860)	-	1518938..1519390 (+)	453	WP_164178276.1	universal stress protein	-
STT55_RS07930	-	1519570..1520141 (+)	572	Protein_1509	IS30 family transposase	-
STT55_RS07935 (STT55_07865)	-	1520213..1520386 (-)	174	WP_011681546.1	hypothetical protein	-
STT55_RS07940 (STT55_07870)	-	1520447..1520821 (-)	375	WP_041828320.1	membrane protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=449593 STT55_RS07915 WP_002951720.1 1516324..1517109(-) (codY) [Streptococcus thermophilus strain ST55]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=449593 STT55_RS07915 WP_002951720.1 1516324..1517109(-) (codY) [Streptococcus thermophilus strain ST55]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGTCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502