Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   STMM20_RS00900 Genome accession   NZ_CP065485
Coordinates   175386..176327 (+) Length   313 a.a.
NCBI ID   WP_347103581.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM20     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 170386..181327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM20_RS00890 (STMM20_00930) rpoC 171146..174784 (+) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -
  STMM20_RS00895 (STMM20_00935) - 174943..175305 (+) 363 WP_023909982.1 DUF1033 family protein -
  STMM20_RS00900 (STMM20_00940) comGA 175386..176327 (+) 942 WP_347103581.1 competence type IV pilus ATPase ComGA Machinery gene
  STMM20_RS00905 (STMM20_00945) comGB 176209..177309 (+) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  STMM20_RS00910 (STMM20_00950) comGC 177306..177632 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STMM20_RS00915 (STMM20_00955) comGD 177592..178020 (+) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  STMM20_RS00920 (STMM20_00960) comGE 177992..178285 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STMM20_RS00925 (STMM20_00965) comGF 178269..178706 (+) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  STMM20_RS00930 (STMM20_00970) comGG 178684..179001 (+) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  STMM20_RS00935 (STMM20_00975) comGH 179046..180002 (+) 957 WP_347103582.1 class I SAM-dependent methyltransferase Machinery gene
  STMM20_RS00940 (STMM20_00980) - 180058..181251 (+) 1194 WP_014608740.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35402.57 Da        Isoelectric Point: 6.3072

>NTDB_id=448175 STMM20_RS00900 WP_347103581.1 175386..176327(+) (comGA) [Streptococcus thermophilus strain MM20]
MVTEFAKEMIKNADSCGAQDIYVIPHQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=448175 STMM20_RS00900 WP_347103581.1 175386..176327(+) (comGA) [Streptococcus thermophilus strain MM20]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACATCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus mutans UA159

64.537

100

0.645
  comGA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comGA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377