Detailed information NTG0448180

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: STMM20_RS00925
• Genome accession: NZ_CP065485
• Coordinates: 178269..178706 (+)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM20
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 173269..183706

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM20_RS00895 (STMM20_00935)	-	174943..175305 (+)	363	WP_023909982.1	DUF1033 family protein	-
STMM20_RS00900 (STMM20_00940)	comGA	175386..176327 (+)	942	WP_347103581.1	competence type IV pilus ATPase ComGA	Machinery gene
STMM20_RS00905 (STMM20_00945)	comGB	176209..177309 (+)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STMM20_RS00910 (STMM20_00950)	comGC	177306..177632 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STMM20_RS00915 (STMM20_00955)	comGD	177592..178020 (+)	429	WP_257608452.1	competence type IV pilus minor pilin ComGD	Machinery gene
STMM20_RS00920 (STMM20_00960)	comGE	177992..178285 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
STMM20_RS00925 (STMM20_00965)	comGF	178269..178706 (+)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STMM20_RS00930 (STMM20_00970)	comGG	178684..179001 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
STMM20_RS00935 (STMM20_00975)	comGH	179046..180002 (+)	957	WP_347103582.1	class I SAM-dependent methyltransferase	Machinery gene
STMM20_RS00940 (STMM20_00980)	-	180058..181251 (+)	1194	WP_014608740.1	acetate kinase	-
STMM20_RS00945 (STMM20_00985)	-	181500..181697 (+)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STMM20_RS00950	-	181709..181984 (+)	276	WP_011681681.1	hypothetical protein	-
STMM20_RS00955	-	182028..182366 (+)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
STMM20_RS00960 (STMM20_00995)	-	182440..182883 (+)	444	WP_011681680.1	hypothetical protein	-
STMM20_RS00965 (STMM20_01000)	-	182980..183642 (+)	663	WP_011681679.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=448180 STMM20_RS00925 WP_014608742.1 178269..178706(+) (comGF) [Streptococcus thermophilus strain MM20]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=448180 STMM20_RS00925 WP_014608742.1 178269..178706(+) (comGF) [Streptococcus thermophilus strain MM20]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA140	58.865	97.241	0.572
comGF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441