Detailed information NTG0448176

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: STMM20_RS00905
• Genome accession: NZ_CP065485
• Coordinates: 176209..177309 (+)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM20
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 171209..182309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM20_RS00895 (STMM20_00935)	-	174943..175305 (+)	363	WP_023909982.1	DUF1033 family protein	-
STMM20_RS00900 (STMM20_00940)	comGA	175386..176327 (+)	942	WP_347103581.1	competence type IV pilus ATPase ComGA	Machinery gene
STMM20_RS00905 (STMM20_00945)	comGB	176209..177309 (+)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STMM20_RS00910 (STMM20_00950)	comGC	177306..177632 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STMM20_RS00915 (STMM20_00955)	comGD	177592..178020 (+)	429	WP_257608452.1	competence type IV pilus minor pilin ComGD	Machinery gene
STMM20_RS00920 (STMM20_00960)	comGE	177992..178285 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
STMM20_RS00925 (STMM20_00965)	comGF	178269..178706 (+)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STMM20_RS00930 (STMM20_00970)	comGG	178684..179001 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
STMM20_RS00935 (STMM20_00975)	comGH	179046..180002 (+)	957	WP_347103582.1	class I SAM-dependent methyltransferase	Machinery gene
STMM20_RS00940 (STMM20_00980)	-	180058..181251 (+)	1194	WP_014608740.1	acetate kinase	-
STMM20_RS00945 (STMM20_00985)	-	181500..181697 (+)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STMM20_RS00950	-	181709..181984 (+)	276	WP_011681681.1	hypothetical protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=448176 STMM20_RS00905 WP_120764773.1 176209..177309(+) (comGB) [Streptococcus thermophilus strain MM20]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=448176 STMM20_RS00905 WP_120764773.1 176209..177309(+) (comGB) [Streptococcus thermophilus strain MM20]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTCATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	54.678	93.443	0.511
comGB	Streptococcus mutans UA159	54.678	93.443	0.511
comGB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413