Detailed information NTG0447315

Bioinformatically predicted

Overview

• Name: recD/recD2/recDB
• Type: Machinery gene
• Locus tag: ST4052_RS08020
• Genome accession: NZ_CP065476
• Coordinates: 1552252..1554756 (+)
• Length: 834 a.a.
• NCBI ID: WP_011226558.1
• Uniprot ID: Q5M2P0
• Organism: Streptococcus thermophilus strain 4052
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1547252..1559756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4052_RS08000 (ST4052_08070)	-	1549488..1550030 (-)	543	WP_011227557.1	CvpA family protein	-
ST4052_RS08005 (ST4052_08075)	-	1550027..1550344 (-)	318	WP_002947863.1	hypothetical protein	-
ST4052_RS08010 (ST4052_08080)	rnhC	1550658..1551548 (+)	891	WP_011227558.1	ribonuclease HIII	-
ST4052_RS08015 (ST4052_08085)	lepB	1551567..1552190 (+)	624	WP_002947854.1	signal peptidase I	-
ST4052_RS08020 (ST4052_08090)	recD/recD2/recDB	1552252..1554756 (+)	2505	WP_011226558.1	ATP-dependent RecD-like DNA helicase	Machinery gene
ST4052_RS08025 (ST4052_08095)	-	1554812..1555138 (-)	327	WP_011226559.1	AzlD domain-containing protein	-
ST4052_RS08030 (ST4052_08100)	-	1555125..1555796 (-)	672	WP_041827165.1	AzlC family ABC transporter permease	-
ST4052_RS08035 (ST4052_08105)	tsaD	1555869..1556882 (-)	1014	WP_002951922.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
ST4052_RS08040 (ST4052_08110)	rimI	1556882..1557295 (-)	414	WP_014621963.1	ribosomal protein S18-alanine N-acetyltransferase	-
ST4052_RS08045 (ST4052_08115)	tsaB	1557297..1557983 (-)	687	WP_002947108.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	-
ST4052_RS08050 (ST4052_08120)	-	1558247..1558477 (+)	231	WP_002947111.1	DNA-dependent RNA polymerase subunit epsilon	-

Sequence

Protein

• Length: 834 a.a.
• Molecular weight: 94209.60 Da
• Isoelectric Point: 4.5917

>NTDB_id=447315 ST4052_RS08020 WP_011226558.1 1552252..1554756(+) (recD/recD2/recDB) [Streptococcus thermophilus strain 4052]
MQEFYFSGTIERIIFENASNFFRILLLEIDETDSDFEDYEIIVTGTMGDVMEGEDYTFWGQLTNHPKYGKQLQMTRYERS
KPSASGLIKYFSSDNFKGIGKKTAERIVEIYGEDPIDKILEDPSKLEQIPNLSKVNREAFLAKLKINYGTEQILSKLSSY
GLTPKAASQIFNQYKEESLNLIEKYPYLLVEEVQGIGFKMADQLAERLGIASDAPERLRAALIHCLLEASMEEGDTYIEA
KSLLERTIILLESSRQIELDPALVAHQLTNLIQEDKVQNIETKIFDNTLYFAEQGIYTHLTRITKDQPDISAEDKIQASL
ERVEDELGITYDKVQKDAIIKALQSKVFILTGGPGTGKTTVINGIIKTYADLHGLDLKKSDLPIILAAPTGRAARRMNEL
TKLPSATIHRHLGLNGEDDFKTLDDYLDCDLIIIDEFSMVDTWLANQLFESISDTTQVIIVGDQDQLPSVGPGQVLADLL
QIDDLPKVSLTKIFRQSEDSTIVTLASQIRQGQLPTDFTEKKADRSYFEANANHIPQMVPKIVSAAIKSGIAAQDVQILA
PMYRGQAGINNLNTIMQDLLNPKEKANQFAFNDIFFRKNDKILHLVNDTELNVFNGDIGIITDLIPGKYTESKQDEIYMS
FDGNEVIYPRNEWNKITLAYAMSIHKSQGSEFPVVILPITRQSGRMLQRNLIYTAITRAKSKLVMLGEIAAFDYAVHNEG
AKRNTYLIQRFEQTYTQAVDKSVEKNVKNEGTDAFNQTKTENNRPSETLENKDFSENINPSQTLINTYSHPVDKSVNKPV
QTEENYRLTEENWATIDPMIGLSEDDIAAFFNNN

Nucleotide

• Length: 2505 bp

>NTDB_id=447315 ST4052_RS08020 WP_011226558.1 1552252..1554756(+) (recD/recD2/recDB) [Streptococcus thermophilus strain 4052]
ATGCAAGAATTTTATTTTTCAGGAACTATCGAGCGCATCATTTTTGAAAATGCCAGTAATTTTTTTCGTATCCTACTCTT
AGAAATTGATGAAACTGACAGTGATTTTGAAGACTATGAAATCATTGTTACTGGAACTATGGGGGATGTCATGGAGGGGG
AAGACTATACCTTCTGGGGTCAGCTAACCAATCACCCCAAATATGGCAAACAACTCCAAATGACTCGCTACGAGCGTTCA
AAACCCTCTGCCAGTGGCCTTATCAAATATTTCTCCAGTGATAATTTCAAAGGAATCGGTAAGAAAACGGCCGAGCGTAT
TGTCGAGATTTATGGCGAAGACCCTATTGACAAGATTCTCGAAGACCCTAGTAAATTAGAACAGATTCCTAATCTGTCCA
AGGTAAACCGAGAAGCCTTCCTTGCAAAATTAAAAATCAACTATGGTACTGAACAAATCTTGTCCAAACTTTCCAGCTAT
GGACTCACACCAAAGGCTGCCTCACAAATTTTCAACCAATATAAGGAAGAATCACTTAACCTTATCGAAAAATATCCTTA
TCTCTTGGTAGAGGAAGTCCAGGGAATTGGATTTAAAATGGCCGATCAACTAGCCGAACGCCTAGGGATTGCTAGCGATG
CTCCTGAGCGTTTACGAGCCGCCCTAATTCACTGTCTGCTAGAAGCTAGTATGGAAGAAGGGGACACCTACATCGAAGCC
AAGTCCTTGCTTGAACGGACTATCATTCTTTTGGAAAGTTCTCGCCAGATTGAACTTGACCCTGCCTTGGTTGCTCACCA
ATTAACCAACCTCATCCAAGAGGATAAGGTGCAAAATATAGAGACTAAAATTTTTGATAATACCCTATATTTTGCAGAAC
AGGGCATCTATACCCACCTAACTCGTATCACGAAAGACCAGCCTGACATCAGTGCTGAGGACAAAATCCAAGCAAGTCTT
GAAAGGGTGGAAGATGAGCTTGGTATCACCTATGACAAGGTTCAAAAAGATGCCATTATTAAAGCCCTACAAAGCAAGGT
CTTCATCCTGACAGGTGGTCCCGGAACAGGAAAAACCACTGTTATTAACGGAATTATTAAAACCTATGCTGACCTTCATG
GTTTAGACCTCAAAAAGTCTGATTTACCCATTATTTTAGCAGCGCCAACGGGACGGGCTGCTCGTCGGATGAACGAACTG
ACCAAGCTCCCTAGTGCCACTATCCATAGACATTTGGGGCTTAATGGCGAGGACGATTTCAAGACCTTAGATGACTATCT
CGATTGCGATTTGATTATCATCGATGAGTTCTCTATGGTTGATACTTGGTTGGCCAATCAACTCTTCGAAAGCATTTCCG
ATACTACTCAAGTAATCATTGTAGGTGACCAAGATCAGCTACCTTCTGTAGGCCCTGGCCAAGTCTTAGCTGACCTTTTG
CAGATTGATGACTTGCCTAAGGTTTCCCTAACCAAAATTTTCAGACAATCTGAGGATTCCACTATTGTTACCTTAGCTAG
CCAGATACGCCAAGGCCAACTACCCACTGATTTCACAGAGAAAAAAGCTGACCGATCATACTTTGAGGCTAATGCTAACC
ATATTCCACAGATGGTCCCTAAAATTGTCTCTGCCGCTATTAAAAGTGGGATCGCTGCTCAGGATGTACAGATTCTGGCC
CCCATGTACCGGGGACAGGCTGGTATCAACAATCTCAATACCATTATGCAGGATCTACTTAATCCCAAAGAAAAAGCCAA
TCAATTTGCCTTTAATGATATTTTCTTCCGTAAGAATGACAAGATTCTCCACCTGGTCAACGATACAGAACTCAATGTCT
TCAATGGCGATATCGGAATCATTACTGATCTCATACCTGGTAAATATACTGAAAGTAAGCAAGACGAAATTTACATGTCC
TTCGATGGCAATGAGGTTATCTATCCTCGTAACGAATGGAATAAGATTACTCTGGCCTATGCCATGTCTATACACAAATC
CCAAGGGAGTGAATTCCCAGTCGTTATCCTTCCCATCACACGCCAAAGTGGGCGTATGCTTCAACGTAACCTCATCTACA
CCGCTATCACACGCGCCAAGAGTAAACTGGTCATGTTGGGGGAAATCGCAGCCTTCGATTATGCCGTTCACAACGAGGGG
GCCAAACGTAATACCTACCTCATCCAACGTTTTGAACAAACTTATACACAAGCTGTTGATAAGTCTGTCGAAAAGAATGT
TAAAAACGAGGGAACAGACGCCTTCAATCAAACAAAAACGGAAAACAATAGACCCTCAGAAACCCTTGAAAACAAAGACT
TCTCGGAAAATATCAATCCATCCCAAACTCTTATTAACACTTATTCACATCCTGTGGATAAGTCTGTTAACAAACCTGTG
CAAACAGAAGAAAACTATCGTTTAACTGAAGAAAACTGGGCAACTATCGACCCAATGATAGGTCTCAGCGAAGACGATAT
TGCAGCCTTTTTTAACAACAACTAG

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C_2) (659-705)

• AAA domain (AAA_30) (331-524)

• Helix-hairpin-helix containing domain (HHH_RecD2) (147-237)

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (572-638)

3D structure

• AlphaFold DB: Q5M2P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD/recD2/recDB	Bacillus subtilis subsp. subtilis str. 168	44.712	89.568	0.4