Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GE022_RS00845 Genome accession   NZ_CP053790
Coordinates   141114..142055 (+) Length   313 a.a.
NCBI ID   WP_003046182.1    Uniprot ID   A0AAV3FPU3
Organism   Streptococcus canis strain HL_77_2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136114..147055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS00835 (GE022_000835) rpoC 136875..140516 (+) 3642 WP_164405638.1 DNA-directed RNA polymerase subunit beta' -
  GE022_RS00840 (GE022_000840) - 140662..141027 (+) 366 WP_125073632.1 DUF1033 family protein -
  GE022_RS00845 (GE022_000845) comYA 141114..142055 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE022_RS00850 (GE022_000850) comYB 141988..143022 (+) 1035 WP_172758339.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE022_RS00855 (GE022_000855) comYC 143025..143351 (+) 327 WP_164405637.1 competence type IV pilus major pilin ComGC Machinery gene
  GE022_RS00860 (GE022_000860) comGD 143326..143754 (+) 429 WP_276509017.1 competence type IV pilus minor pilin ComGD -
  GE022_RS00865 (GE022_000865) comGE 143762..144007 (+) 246 WP_051026419.1 competence type IV pilus minor pilin ComGE -
  GE022_RS00870 (GE022_000870) comGF 143988..144428 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF -
  GE022_RS00875 (GE022_000875) comGG 144406..144786 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE022_RS00880 (GE022_000880) comYH 144836..145789 (+) 954 WP_164405635.1 class I SAM-dependent methyltransferase Machinery gene
  GE022_RS00885 (GE022_000885) - 145848..147044 (+) 1197 WP_093998734.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35350.57 Da        Isoelectric Point: 7.5355

>NTDB_id=447193 GE022_RS00845 WP_003046182.1 141114..142055(+) (comYA) [Streptococcus canis strain HL_77_2]
MVQALAKSILKEAEQVQAQDIYILPRADQYELFLRIGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
LDEDTRLSLRLSSVGDYRGQESLVIRLLHHQKKELRYWFDGLTKVASQIGGRGLYLFAGPVGSGKTTLMHQLIADHYQEA
QVISIEDPVEIKNQQALQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTRAELDNCLALIAYQRLLNGGALIDATQKNFEHYLPDRWNQQLDQLLAAGHLSPKQARLEKIVQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=447193 GE022_RS00845 WP_003046182.1 141114..142055(+) (comYA) [Streptococcus canis strain HL_77_2]
ATGGTACAAGCATTAGCAAAATCAATTTTGAAAGAAGCAGAGCAAGTTCAGGCTCAAGATATTTATATTCTGCCACGAGC
AGACCAGTACGAGCTCTTTTTAAGAATAGGAGATGAAAGGAGATTAGTAGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGACCGTTGGTGAAAAAAGACGTTGTCAGGTTGGTTCTTGTGATTATGAC
CTTGATGAAGACACGCGATTGTCCTTACGTTTATCCAGTGTTGGAGATTACCGTGGTCAAGAAAGTTTAGTCATTCGTCT
GCTACATCATCAGAAAAAGGAGTTACGTTACTGGTTTGATGGATTAACTAAAGTAGCGAGTCAGATTGGAGGTCGAGGCC
TCTACCTTTTTGCAGGTCCAGTCGGATCAGGGAAAACAACTTTGATGCATCAGCTTATTGCAGATCATTATCAGGAAGCA
CAGGTGATTAGCATTGAAGATCCAGTGGAAATTAAAAACCAGCAGGCCTTACAATTGCAAGTCAATGATGATATTGGCAT
GACTTACGACAATTTAATCAAACTGTCCTTGCGGCATCGACCAGATATTTTGGTCATTGGTGAAATTCGAGATAGCCAGA
CAGCTAGAGCAGTTATTAGAGCCAGTCTAACAGGGGCCATGGTCTTTTCAACGGTGCATGCCAAAAGTATTTCAGGAGTC
TATGCTAGATTGCTAGAACTTGGGGTAACAAGGGCAGAGCTGGATAATTGTTTGGCCTTAATTGCCTACCAACGTTTGCT
TAATGGAGGAGCATTGATTGACGCAACTCAAAAAAACTTTGAACACTACCTACCAGACCGGTGGAATCAGCAGCTTGATC
AGTTACTTGCAGCAGGACATCTCAGTCCGAAACAAGCAAGGCTTGAAAAAATTGTCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

62.379

99.361

0.62
  comYA Streptococcus mutans UA140

61.736

99.361

0.613
  comYA Streptococcus mutans UA159

61.736

99.361

0.613
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.361

0.588
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

39.86

91.374

0.364