Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   GE022_RS00850 Genome accession   NZ_CP053790
Coordinates   141988..143022 (+) Length   344 a.a.
NCBI ID   WP_172758339.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136988..148022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS00840 (GE022_000840) - 140662..141027 (+) 366 WP_125073632.1 DUF1033 family protein -
  GE022_RS00845 (GE022_000845) comYA 141114..142055 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE022_RS00850 (GE022_000850) comYB 141988..143022 (+) 1035 WP_172758339.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE022_RS00855 (GE022_000855) comYC 143025..143351 (+) 327 WP_164405637.1 competence type IV pilus major pilin ComGC Machinery gene
  GE022_RS00860 (GE022_000860) comGD 143326..143754 (+) 429 WP_276509017.1 competence type IV pilus minor pilin ComGD -
  GE022_RS00865 (GE022_000865) comGE 143762..144007 (+) 246 WP_051026419.1 competence type IV pilus minor pilin ComGE -
  GE022_RS00870 (GE022_000870) comGF 143988..144428 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF -
  GE022_RS00875 (GE022_000875) comGG 144406..144786 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE022_RS00880 (GE022_000880) comYH 144836..145789 (+) 954 WP_164405635.1 class I SAM-dependent methyltransferase Machinery gene
  GE022_RS00885 (GE022_000885) - 145848..147044 (+) 1197 WP_093998734.1 acetate kinase -
  GE022_RS00890 (GE022_000890) - 147336..147542 (+) 207 WP_164405634.1 helix-turn-helix transcriptional regulator -
  GE022_RS00895 (GE022_000895) - 147543..147683 (+) 141 Protein_131 type II CAAX prenyl endopeptidase Rce1 family protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39287.63 Da        Isoelectric Point: 9.0224

>NTDB_id=447194 GE022_RS00850 WP_172758339.1 141988..143022(+) (comYB) [Streptococcus canis strain HL_77_2]
MISYLQQDISVRNKQGLKKLSSKEQYKLIQLLTNLLSAGFQLTDIIAFLKKSQLVKLQYVLSMEDSLLKGRGLADMLAGL
GFSDAILTQISLADGHGDIKKTLFNIQNYLKQMTQLKRKTIEVITYPIMLLLFLFVIMLGLRHYLVPQLEETNQITDFLN
HFPTYFLGFCLALVLLLGVGWLRWRSQSRLNCLSHLSTFPFLGKLLQQYLTAYYAREWGTLIGQGLELPMILDIMATEKS
SLMQELAEDIRASLLAGQAFPTKVATYPFFKKELSLMIEYGEIKSKLGQELEIYAQESWARFFSQLHQATQFIQPVIFLM
IALIIVMIYAAILLPIYQDMGGLI

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=447194 GE022_RS00850 WP_172758339.1 141988..143022(+) (comYB) [Streptococcus canis strain HL_77_2]
TTGATCAGTTACTTGCAGCAGGACATCTCAGTCCGAAACAAGCAAGGCTTGAAAAAATTGTCCAGTAAAGAGCAATATAA
GCTTATTCAGTTGTTGACTAATCTTCTATCAGCAGGATTTCAGTTGACAGATATTATTGCTTTTTTAAAGAAAAGTCAGC
TTGTGAAACTCCAGTATGTTCTTAGTATGGAAGATTCCCTTTTAAAGGGACGAGGCTTAGCAGATATGTTAGCTGGTCTG
GGATTTTCGGATGCCATCTTGACTCAGATTAGCCTAGCAGATGGGCACGGAGATATTAAGAAGACGCTGTTTAACATTCA
GAATTACCTGAAGCAAATGACCCAGCTCAAACGAAAAACCATTGAAGTAATAACCTATCCAATAATGCTGTTGCTTTTTC
TCTTTGTCATCATGCTAGGATTGAGACACTATTTAGTGCCCCAATTAGAAGAGACAAACCAAATAACTGACTTTCTCAAT
CATTTTCCGACCTACTTTTTGGGTTTTTGTTTGGCTCTTGTGTTACTTTTGGGAGTGGGGTGGCTGAGATGGCGGTCTCA
AAGCCGTTTAAACTGTTTAAGCCACCTAAGCACCTTTCCCTTTCTGGGAAAACTGTTACAACAATACCTAACCGCCTATT
ATGCAAGGGAATGGGGCACTTTGATAGGGCAGGGCCTTGAGTTACCGATGATTCTAGACATTATGGCAACCGAGAAATCC
TCACTGATGCAAGAGTTGGCTGAGGATATTAGGGCTAGTTTACTGGCAGGACAGGCTTTTCCTACCAAAGTAGCCACTTA
CCCTTTCTTTAAAAAAGAATTAAGTTTGATGATTGAATATGGAGAAATCAAATCCAAACTAGGTCAGGAGCTTGAAATCT
ATGCTCAAGAAAGTTGGGCTCGCTTTTTCAGCCAGCTTCATCAAGCAACGCAGTTTATTCAACCAGTTATTTTTTTAATG
ATTGCCTTAATAATCGTCATGATTTATGCGGCAATCTTATTACCAATTTACCAAGATATGGGAGGCCTTATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.392

98.547

0.526
  comYB Streptococcus mutans UA159

53.392

98.547

0.526
  comYB Streptococcus gordonii str. Challis substr. CH1

50

98.837

0.494
  comGB/cglB Streptococcus mitis SK321

46.847

96.802

0.453
  comGB/cglB Streptococcus mitis NCTC 12261

46.269

97.384

0.451
  comGB/cglB Streptococcus pneumoniae Rx1

44.745

96.802

0.433
  comGB/cglB Streptococcus pneumoniae D39

44.745

96.802

0.433
  comGB/cglB Streptococcus pneumoniae R6

44.745

96.802

0.433
  comGB/cglB Streptococcus pneumoniae TIGR4

44.745

96.802

0.433
  comGB Lactococcus lactis subsp. cremoris KW2

42.899

98.256

0.422