Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HPQ66_RS05675 Genome accession   NZ_CP053764
Coordinates   1135259..1135915 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain B268     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1130259..1140915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPQ66_RS05650 (HPQ66_05660) oppF 1130788..1131705 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HPQ66_RS05655 (HPQ66_05665) - 1131812..1132999 (+) 1188 WP_172614591.1 putative glycoside hydrolase -
  HPQ66_RS05660 (HPQ66_05670) - 1133117..1133695 (+) 579 WP_172614592.1 GNAT family N-acetyltransferase -
  HPQ66_RS05665 (HPQ66_05675) spx 1133874..1134269 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HPQ66_RS05670 (HPQ66_05680) - 1134327..1134983 (-) 657 WP_003155033.1 TerC family protein -
  HPQ66_RS05675 (HPQ66_05685) mecA 1135259..1135915 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HPQ66_RS05680 (HPQ66_05690) - 1136066..1137226 (+) 1161 WP_128574781.1 competence protein CoiA family protein -
  HPQ66_RS05685 (HPQ66_05695) pepF 1137454..1139283 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  HPQ66_RS05690 (HPQ66_05700) - 1139321..1139488 (-) 168 WP_165408905.1 hypothetical protein -
  HPQ66_RS05695 (HPQ66_05705) spxH 1139774..1140676 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=446973 HPQ66_RS05675 WP_003155032.1 1135259..1135915(+) (mecA) [Bacillus velezensis strain B268]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=446973 HPQ66_RS05675 WP_003155032.1 1135259..1135915(+) (mecA) [Bacillus velezensis strain B268]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895