Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   MGAS15252_RS00590 Genome accession   NC_017040
Coordinates   97784..98110 (+) Length   108 a.a.
NCBI ID   WP_014407214.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS15252     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92784..103110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS00575 (MGAS15252_0119) - 95430..95795 (+) 366 WP_002986560.1 DUF1033 family protein -
  MGAS15252_RS00580 (MGAS15252_0120) comGA 95888..96812 (+) 925 Protein_81 competence type IV pilus ATPase ComGA -
  MGAS15252_RS00585 (MGAS15252_0121) comYB 96748..97782 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGAS15252_RS00590 (MGAS15252_0122) comGC 97784..98110 (+) 327 WP_014407214.1 competence type IV pilus major pilin ComGC Machinery gene
  MGAS15252_RS00595 (MGAS15252_0123) comGD 98085..98513 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  MGAS15252_RS00600 (MGAS15252_0124) comGE 98470..98754 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  MGAS15252_RS00605 (MGAS15252_0125) comYF 98747..99181 (+) 435 WP_014407215.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGAS15252_RS00610 (MGAS15252_0126) comGG 99165..99491 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  MGAS15252_RS00615 (MGAS15252_0127) comYH 99589..100542 (+) 954 WP_014407216.1 class I SAM-dependent methyltransferase Machinery gene
  MGAS15252_RS00620 (MGAS15252_0128) - 100601..101797 (+) 1197 WP_014407217.1 acetate kinase -
  MGAS15252_RS00625 (MGAS15252_0129) - 101984..102292 (+) 309 WP_041174321.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12390.39 Da        Isoelectric Point: 9.8992

>NTDB_id=44378 MGAS15252_RS00590 WP_014407214.1 97784..98110(+) (comGC) [Streptococcus pyogenes MGAS15252]
MINQWNNLRHKKLKGFTLLEMLLVILVISILMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=44378 MGAS15252_RS00590 WP_014407214.1 97784..98110(+) (comGC) [Streptococcus pyogenes MGAS15252]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTATTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

57.843

94.444

0.546
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

56.25

88.889

0.5
  comYC Streptococcus mutans UA159

56.25

88.889

0.5
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment