Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | MGAS15252_RS00615 | Genome accession | NC_017040 |
| Coordinates | 99589..100542 (+) | Length | 317 a.a. |
| NCBI ID | WP_014407216.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes MGAS15252 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 94589..105542
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGAS15252_RS00575 (MGAS15252_0119) | - | 95430..95795 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| MGAS15252_RS00580 (MGAS15252_0120) | comGA | 95888..96812 (+) | 925 | Protein_81 | competence type IV pilus ATPase ComGA | - |
| MGAS15252_RS00585 (MGAS15252_0121) | comYB | 96748..97782 (+) | 1035 | WP_227868709.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| MGAS15252_RS00590 (MGAS15252_0122) | comGC | 97784..98110 (+) | 327 | WP_014407214.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| MGAS15252_RS00595 (MGAS15252_0123) | comGD | 98085..98513 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| MGAS15252_RS00600 (MGAS15252_0124) | comGE | 98470..98754 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| MGAS15252_RS00605 (MGAS15252_0125) | comYF | 98747..99181 (+) | 435 | WP_014407215.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| MGAS15252_RS00610 (MGAS15252_0126) | comGG | 99165..99491 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| MGAS15252_RS00615 (MGAS15252_0127) | comYH | 99589..100542 (+) | 954 | WP_014407216.1 | class I SAM-dependent methyltransferase | Machinery gene |
| MGAS15252_RS00620 (MGAS15252_0128) | - | 100601..101797 (+) | 1197 | WP_014407217.1 | acetate kinase | - |
| MGAS15252_RS00625 (MGAS15252_0129) | - | 101984..102292 (+) | 309 | WP_041174321.1 | hypothetical protein | - |
| MGAS15252_RS00630 (MGAS15252_0130) | proC | 102375..103145 (-) | 771 | WP_014407219.1 | pyrroline-5-carboxylate reductase | - |
| MGAS15252_RS00635 (MGAS15252_0131) | pepA | 103193..104260 (-) | 1068 | WP_014407220.1 | glutamyl aminopeptidase | - |
| MGAS15252_RS00640 (MGAS15252_0133) | - | 104725..105009 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| MGAS15252_RS00645 (MGAS15252_0134) | - | 105006..105323 (+) | 318 | WP_014407222.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36019.09 Da Isoelectric Point: 4.7205
>NTDB_id=44380 MGAS15252_RS00615 WP_014407216.1 99589..100542(+) (comYH) [Streptococcus pyogenes MGAS15252]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVFEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVFEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=44380 MGAS15252_RS00615 WP_014407216.1 99589..100542(+) (comYH) [Streptococcus pyogenes MGAS15252]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTATTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTATTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comYH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |