Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   EGM183_RS08210 Genome accession   NZ_CP050491
Coordinates   1689834..1690109 (-) Length   91 a.a.
NCBI ID   WP_002366896.1    Uniprot ID   -
Organism   Enterococcus faecalis strain EGM183     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1684834..1695109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGM183_RS08170 (EGM183_08180) - 1684880..1685212 (+) 333 WP_002357068.1 hypothetical protein -
  EGM183_RS08175 (EGM183_08185) - 1685389..1685862 (+) 474 WP_002357065.1 universal stress protein -
  EGM183_RS08180 (EGM183_08190) - 1685974..1687161 (-) 1188 WP_002357064.1 acetate/propionate family kinase -
  EGM183_RS08185 (EGM183_08195) - 1687186..1688193 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  EGM183_RS08190 (EGM183_08200) comGG 1688322..1688675 (-) 354 WP_002366892.1 competence type IV pilus minor pilin ComGG -
  EGM183_RS08195 (EGM183_08205) comGF 1688675..1689109 (-) 435 WP_002366893.1 competence type IV pilus minor pilin ComGF -
  EGM183_RS08200 (EGM183_08210) - 1689099..1689425 (-) 327 WP_025186644.1 type II secretion system protein -
  EGM183_RS08205 (EGM183_08215) comGD 1689391..1689837 (-) 447 WP_002366895.1 competence type IV pilus minor pilin ComGD -
  EGM183_RS08210 (EGM183_08220) comGC/cglC 1689834..1690109 (-) 276 WP_002366896.1 competence type IV pilus major pilin ComGC Machinery gene
  EGM183_RS08215 (EGM183_08225) comGB 1690109..1691155 (-) 1047 WP_002366897.1 competence type IV pilus assembly protein ComGB -
  EGM183_RS08220 (EGM183_08230) comGA 1691112..1692080 (-) 969 WP_002374519.1 competence type IV pilus ATPase ComGA -
  EGM183_RS08225 (EGM183_08235) - 1692321..1693649 (-) 1329 WP_002362058.1 APC family permease -
  EGM183_RS08230 (EGM183_08240) rlmN 1693939..1695012 (-) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10492.43 Da        Isoelectric Point: 9.3340

>NTDB_id=433333 EGM183_RS08210 WP_002366896.1 1689834..1690109(-) (comGC/cglC) [Enterococcus faecalis strain EGM183]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNRTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=433333 EGM183_RS08210 WP_002366896.1 1689834..1690109(-) (comGC/cglC) [Enterococcus faecalis strain EGM183]
ATGAAAAAGAAACAAAAATACGCGGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTCCCTAACTTAGCGAAACATAAAGAAACAGTTGACAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTATACACTAGAAAAAAATAGGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582

  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571

  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571

  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549

  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538

  comYC Streptococcus suis isolate S10

52.326

94.505

0.495

  comYC Streptococcus mutans UA159

57.692

85.714

0.495

  comYC Streptococcus mutans UA140

57.692

85.714

0.495

  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462

  comGC Staphylococcus aureus MW2

48.101

86.813

0.418

  comGC Staphylococcus aureus N315

48.101

86.813

0.418

  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396