Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   E3S85_RS02365 Genome accession   NZ_CP047839
Coordinates   447101..447412 (+) Length   103 a.a.
NCBI ID   WP_000472257.1    Uniprot ID   A0A115HMG3
Organism   Staphylococcus aureus strain UP_678     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 442101..452412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S85_RS02335 (E3S85_02335) - 442884..443087 (+) 204 WP_000087561.1 YqgQ family protein -
  E3S85_RS02340 (E3S85_02340) - 443084..444070 (+) 987 WP_000161314.1 ROK family glucokinase -
  E3S85_RS02345 (E3S85_02345) - 444070..444399 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  E3S85_RS02350 (E3S85_02350) - 444396..445019 (+) 624 WP_160175980.1 MBL fold metallo-hydrolase -
  E3S85_RS02355 (E3S85_02355) comGA 445071..446045 (+) 975 WP_160175981.1 competence type IV pilus ATPase ComGA Machinery gene
  E3S85_RS02360 (E3S85_02360) comGB 446017..447087 (+) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  E3S85_RS02365 (E3S85_02365) comGC 447101..447412 (+) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  E3S85_RS02370 (E3S85_02370) comGD 447390..447836 (+) 447 WP_160175982.1 competence type IV pilus minor pilin ComGD Machinery gene
  E3S85_RS02375 (E3S85_02375) comGE 447823..448122 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  E3S85_RS02380 (E3S85_02380) comGF 448040..448537 (+) 498 WP_001794328.1 competence type IV pilus minor pilin ComGF Machinery gene
  E3S85_RS02385 (E3S85_02385) - 448634..448780 (+) 147 WP_001789879.1 hypothetical protein -
  E3S85_RS02390 (E3S85_02390) - 448770..449294 (+) 525 WP_001015125.1 shikimate kinase -
  E3S85_RS02395 (E3S85_02395) gcvT 449453..450544 (+) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -
  E3S85_RS02400 (E3S85_02400) gcvPA 450564..451910 (+) 1347 WP_000019697.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11373.39 Da        Isoelectric Point: 7.8600

>NTDB_id=417549 E3S85_RS02365 WP_000472257.1 447101..447412(+) (comGC) [Staphylococcus aureus strain UP_678]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEEQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=417549 E3S85_RS02365 WP_000472257.1 447101..447412(+) (comGC) [Staphylococcus aureus strain UP_678]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGAGCAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A115HMG3

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99

  comGC Staphylococcus aureus MW2

99.029

100

0.99

  comGC/cglC Streptococcus mitis SK321

48.039

99.029

0.476

  comGC/cglC Streptococcus pneumoniae R6

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae D39

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae TIGR4

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae Rx1

47.059

99.029

0.466

  comGC/cglC Streptococcus mitis NCTC 12261

52.326

83.495

0.437

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comYC Streptococcus mutans UA140

50

73.786

0.369

  comYC Streptococcus mutans UA159

50

73.786

0.369

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369


Multiple sequence alignment