Detailed information NTG0415462

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: H7798_RS00270
• Genome accession: NZ_CP060638
• Coordinates: 48063..49061 (+)
• Length: 332 a.a.
• NCBI ID: WP_011054100.1
• Uniprot ID: P0DF51
• Organism: Streptococcus pyogenes strain TSPY141
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 43063..54061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7798_RS00250 (H7798_00255)	-	44071..45489 (+)	1419	WP_011888524.1	hypothetical protein	-
H7798_RS00255 (H7798_00260)	purB	45509..46801 (+)	1293	WP_111717783.1	adenylosuccinate lyase	-
H7798_RS00260 (H7798_00265)	comR	46932..47843 (+)	912	WP_020904818.1	helix-turn-helix domain-containing protein	Regulator
H7798_RS00265	comS	47934..48032 (+)	99	WP_020833188.1	quorum-sensing system DWW-type pheromone	Regulator
H7798_RS00270 (H7798_00270)	ruvB	48063..49061 (+)	999	WP_011054100.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
H7798_RS00275 (H7798_00275)	-	49199..49636 (+)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
H7798_RS00280 (H7798_00280)	-	49659..50060 (+)	402	WP_002986671.1	MORN repeat-containing protein	-
H7798_RS00285 (H7798_00285)	-	50057..51832 (+)	1776	WP_002987732.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37566.10 Da
• Isoelectric Point: 5.1632

>NTDB_id=415462 H7798_RS00270 WP_011054100.1 48063..49061(+) (ruvB) [Streptococcus pyogenes strain TSPY141]
MARILDNDVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=415462 H7798_RS00270 WP_011054100.1 48063..49061(+) (ruvB) [Streptococcus pyogenes strain TSPY141]
ATGGCTAGAATTTTAGACAATGATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTTGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: P0DF51

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473