Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GE024_RS00840 Genome accession   NZ_CP046521
Coordinates   139108..140049 (+) Length   313 a.a.
NCBI ID   WP_003046182.1    Uniprot ID   A0AAV3FPU3
Organism   Streptococcus canis strain HL_100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 134108..145049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS00830 (GE024_00820) rpoC 134869..138510 (+) 3642 WP_093998736.1 DNA-directed RNA polymerase subunit beta' -
  GE024_RS00835 (GE024_00825) - 138656..139021 (+) 366 WP_003046179.1 DUF1033 family protein -
  GE024_RS00840 (GE024_00830) comYA 139108..140049 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE024_RS00845 (GE024_00835) comYB 139982..141016 (+) 1035 WP_223824829.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE024_RS00850 (GE024_00840) comGC/cglC 141019..141345 (+) 327 WP_003046186.1 competence type IV pilus major pilin ComGC Machinery gene
  GE024_RS00855 (GE024_00845) comGD 141320..141748 (+) 429 WP_039994748.1 competence type IV pilus minor pilin ComGD -
  GE024_RS00860 (GE024_00850) comGE 141726..142001 (+) 276 WP_003046190.1 competence type IV pilus minor pilin ComGE -
  GE024_RS00865 (GE024_00855) comGF 141982..142422 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF -
  GE024_RS00870 (GE024_00860) comGG 142400..142780 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE024_RS00875 (GE024_00865) comYH 142830..143783 (+) 954 WP_003046195.1 class I SAM-dependent methyltransferase Machinery gene
  GE024_RS00880 (GE024_00870) - 143842..145038 (+) 1197 WP_093998734.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35350.57 Da        Isoelectric Point: 7.5355

>NTDB_id=404831 GE024_RS00840 WP_003046182.1 139108..140049(+) (comYA) [Streptococcus canis strain HL_100]
MVQALAKSILKEAEQVQAQDIYILPRADQYELFLRIGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
LDEDTRLSLRLSSVGDYRGQESLVIRLLHHQKKELRYWFDGLTKVASQIGGRGLYLFAGPVGSGKTTLMHQLIADHYQEA
QVISIEDPVEIKNQQALQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTRAELDNCLALIAYQRLLNGGALIDATQKNFEHYLPDRWNQQLDQLLAAGHLSPKQARLEKIVQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=404831 GE024_RS00840 WP_003046182.1 139108..140049(+) (comYA) [Streptococcus canis strain HL_100]
ATGGTACAAGCATTAGCAAAATCAATTTTGAAAGAAGCAGAGCAAGTTCAGGCTCAAGATATTTATATTCTGCCACGAGC
AGACCAGTACGAGCTCTTTTTAAGAATAGGAGATGAAAGGAGATTAGTAGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGACCGTTGGTGAAAAAAGACGTTGTCAGGTTGGTTCTTGTGATTATGAC
CTTGATGAAGACACGCGATTGTCCTTACGTTTATCCAGTGTTGGAGATTACCGTGGTCAAGAAAGTTTAGTCATTCGTCT
GCTACATCATCAGAAAAAGGAGTTACGTTACTGGTTTGATGGATTAACTAAAGTAGCGAGTCAGATTGGAGGTCGAGGCC
TCTACCTTTTTGCAGGTCCAGTCGGATCAGGGAAAACAACTTTGATGCATCAGCTTATTGCAGATCATTATCAGGAAGCA
CAGGTGATTAGCATTGAAGATCCAGTGGAAATTAAAAACCAGCAGGCCTTACAATTGCAAGTCAATGATGATATTGGCAT
GACTTACGACAATTTAATCAAACTGTCCTTGCGGCATCGACCAGATATTTTGGTCATTGGTGAAATTCGAGATAGCCAGA
CAGCTAGAGCAGTTATTAGAGCCAGTCTAACAGGGGCCATGGTCTTTTCAACGGTGCATGCCAAAAGTATTTCAGGAGTC
TATGCTAGATTGCTAGAACTTGGGGTAACAAGGGCAGAACTGGATAATTGTTTGGCCTTAATTGCCTACCAACGTTTGCT
TAATGGAGGAGCATTGATTGACGCAACTCAAAAAAACTTTGAACACTACCTACCAGACCGGTGGAATCAGCAGCTTGATC
AGTTACTTGCAGCAGGACATCTCAGTCCGAAACAAGCAAGGCTTGAAAAAATTGTCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

62.379

99.361

0.62
  comYA Streptococcus mutans UA140

61.736

99.361

0.613
  comYA Streptococcus mutans UA159

61.736

99.361

0.613
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.361

0.588
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

39.86

91.374

0.364

Multiple sequence alignment