Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   GE024_RS00850 Genome accession   NZ_CP046521
Coordinates   141019..141345 (+) Length   108 a.a.
NCBI ID   WP_003046186.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136019..146345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS00835 (GE024_00825) - 138656..139021 (+) 366 WP_003046179.1 DUF1033 family protein -
  GE024_RS00840 (GE024_00830) comYA 139108..140049 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE024_RS00845 (GE024_00835) comYB 139982..141016 (+) 1035 WP_223824829.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE024_RS00850 (GE024_00840) comGC/cglC 141019..141345 (+) 327 WP_003046186.1 competence type IV pilus major pilin ComGC Machinery gene
  GE024_RS00855 (GE024_00845) comGD 141320..141748 (+) 429 WP_039994748.1 competence type IV pilus minor pilin ComGD -
  GE024_RS00860 (GE024_00850) comGE 141726..142001 (+) 276 WP_003046190.1 competence type IV pilus minor pilin ComGE -
  GE024_RS00865 (GE024_00855) comGF 141982..142422 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF -
  GE024_RS00870 (GE024_00860) comGG 142400..142780 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE024_RS00875 (GE024_00865) comYH 142830..143783 (+) 954 WP_003046195.1 class I SAM-dependent methyltransferase Machinery gene
  GE024_RS00880 (GE024_00870) - 143842..145038 (+) 1197 WP_093998734.1 acetate kinase -
  GE024_RS00885 (GE024_00875) - 145330..145536 (+) 207 WP_003046200.1 helix-turn-helix transcriptional regulator -
  GE024_RS11045 (GE024_00885) - 145694..146131 (+) 438 WP_164403311.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12391.29 Da        Isoelectric Point: 9.3348

>NTDB_id=404833 GE024_RS00850 WP_003046186.1 141019..141345(+) (comGC/cglC) [Streptococcus canis strain HL_100]
MTNQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGHTAVVKLVENQAELYELSQGSKPSLSQLKE
DGSITDKQEKAYRDYYGKHKDEKASLND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=404833 GE024_RS00850 WP_003046186.1 141019..141345(+) (comGC/cglC) [Streptococcus canis strain HL_100]
ATGACAAACCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCAAATTTAAGCAAGCAAAAAGACAGGGTTACCGAGACAGGTCATACCGCTG
TTGTTAAATTAGTGGAGAATCAAGCGGAGCTATATGAATTATCTCAGGGTTCAAAACCAAGTTTGAGCCAACTGAAGGAA
GATGGTAGCATCACTGACAAACAAGAAAAAGCTTATCGCGACTATTATGGCAAACATAAAGATGAAAAAGCCAGTCTTAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

55.446

93.519

0.519
  comYC Streptococcus gordonii str. Challis substr. CH1

56.566

91.667

0.519
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comGC/cglC Streptococcus pneumoniae R6

50.926

100

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

50.926

100

0.509
  comGC/cglC Streptococcus pneumoniae D39

50.926

100

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

53.465

93.519

0.5
  comGC/cglC Streptococcus mitis NCTC 12261

57.609

85.185

0.491
  comYC Streptococcus mutans UA140

58.621

80.556

0.472
  comYC Streptococcus mutans UA159

58.621

80.556

0.472
  comYC Streptococcus suis isolate S10

52.273

81.481

0.426

Multiple sequence alignment