Detailed information NTG0040148

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SSAL_RS01680
• Genome accession: NC_017594
• Coordinates: 328557..329297 (-)
• Length: 246 a.a.
• NCBI ID: WP_013991119.1
• Uniprot ID: -
• Organism: Streptococcus salivarius 57.I
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 323557..334297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL_RS01660 (Ssal_00351)	-	323600..325345 (+)	1746	WP_045001456.1	ABC transporter ATP-binding protein	-
SSAL_RS01665 (Ssal_00352)	-	325505..325735 (+)	231	WP_014632652.1	Blp family class II bacteriocin	-
SSAL_RS10170 (Ssal_00355)	-	326224..326391 (+)	168	WP_013991122.1	hypothetical protein	-
SSAL_RS10360	-	326738..327139 (+)	402	WP_013991121.1	hypothetical protein	-
SSAL_RS10235	comD/comD3	327226..327975 (-)	750	WP_013991120.1	GHKL domain-containing protein	Regulator
SSAL_RS01680 (Ssal_00357)	comE/blpR	328557..329297 (-)	741	WP_013991119.1	response regulator transcription factor	Regulator
SSAL_RS01685	-	329556..329621 (+)	66	Protein_328	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SSAL_RS01690	-	329630..330022 (+)	393	WP_003094909.1	hypothetical protein	-
SSAL_RS01695 (Ssal_00359)	-	330492..330788 (+)	297	WP_013991117.1	bacteriocin immunity protein	-
SSAL_RS01700 (Ssal_00360)	-	331006..331371 (+)	366	WP_013991116.1	hypothetical protein	-
SSAL_RS01710 (Ssal_00362)	tnpA	332081..332497 (+)	417	WP_002886752.1	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28672.25 Da
• Isoelectric Point: 7.9396

>NTDB_id=40148 SSAL_RS01680 WP_013991119.1 328557..329297(-) (comE/blpR) [Streptococcus salivarius 57.I]
MEIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIEIKGEKLKGLDIAKIIREKN
PYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIHIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
KRRNLQ

Nucleotide

• Length: 741 bp

>NTDB_id=40148 SSAL_RS01680 WP_013991119.1 328557..329297(-) (comE/blpR) [Streptococcus salivarius 57.I]
TTGGAAATTTATATTTTAGAGGACAATCTCATTCAACAAGGACGACTGGAGATGGTATTGTCTCAAGAGTTAAAAAAATA
CAATAAAGACTTATCTATTGTACACACCTTTGATAAGCCTCAGCAATTTATAGAAGCGATTGATTCAACAACTTCTAACC
AGCTCTTTTTTCTTGATATCGAAATTAAGGGAGAAAAATTAAAAGGGCTCGATATTGCTAAAATCATTAGGGAAAAAAAT
CCCTACGCTACTATTATCTTTGTCACTACCCACTCAGAGTTTATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATCGATAAAAGTCTCTCTGAAATAGAATTTAGGAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GAATAGAGAATGACGAGATTTTTGATTTTCAAACACAACATACAGCTATTCACATCCCTTTAAACCAAGTTATCTATATT
GAAACTTCTCCGCAAAAGCATTATGTGATACTCCATGGTACAAACAATCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCATCGTTCGTATCTCATTAACCCTAACAACATTATAAGAATCAACAAAT
TAAAACGTGAAGTCGAAATGACTGATGGTAGTATCTGTCCTTTTTCACGTACCAAAGCTAAAATGCTGATGGATACTTTT
AAAAGAAGGAACCTTCAATGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (150-239)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	43.59	95.122	0.415
comE/comE2	Streptococcus gordonii strain NCTC7865	36.8	100	0.374
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.8	100	0.374
comE/comE2	Streptococcus equinus JB1	38.397	96.341	0.37
comE/comE1	Streptococcus equinus JB1	37.815	96.748	0.366
comE	Streptococcus pneumoniae TIGR4	35.6	100	0.362
comE	Streptococcus mitis SK321	35.6	100	0.362
comE	Streptococcus mitis NCTC 12261	35.6	100	0.362
comE	Streptococcus infantis strain Atu-4	35.6	100	0.362
comE	Streptococcus pneumoniae Rx1	35.6	100	0.362
comE	Streptococcus pneumoniae D39	35.6	100	0.362
comE	Streptococcus pneumoniae R6	35.6	100	0.362