Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   GIO26_RS03935 Genome accession   NZ_CP046022
Coordinates   822787..823062 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain BFF1B1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 817787..828062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GIO26_RS03900 - 818349..818822 (+) 474 WP_002357065.1 universal stress protein -
  GIO26_RS03905 - 818927..820114 (-) 1188 WP_002357064.1 acetate kinase -
  GIO26_RS03910 - 820139..821146 (-) 1008 WP_002380426.1 class I SAM-dependent methyltransferase -
  GIO26_RS03915 comGG 821275..821628 (-) 354 WP_002362054.1 competence type IV pilus minor pilin ComGG -
  GIO26_RS03920 comGF 821628..822032 (-) 405 Protein_781 competence type IV pilus minor pilin ComGF -
  GIO26_RS03925 - 822052..822378 (-) 327 WP_025189556.1 type II secretion system protein -
  GIO26_RS03930 comGD 822344..822790 (-) 447 WP_002366895.1 competence type IV pilus minor pilin ComGD -
  GIO26_RS03935 comGC/cglC 822787..823062 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  GIO26_RS03940 comGB 823062..824108 (-) 1047 WP_002369171.1 competence type IV pilus assembly protein ComGB -
  GIO26_RS03945 comGA 824065..825033 (-) 969 WP_207578985.1 competence type IV pilus ATPase ComGA -
  GIO26_RS03950 - 825274..826602 (-) 1329 WP_002360022.1 amino acid permease -
  GIO26_RS03955 rlmN 826892..827965 (-) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=400227 GIO26_RS03935 WP_002356991.1 822787..823062(-) (comGC/cglC) [Enterococcus faecalis strain BFF1B1]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=400227 GIO26_RS03935 WP_002356991.1 822787..823062(-) (comGC/cglC) [Enterococcus faecalis strain BFF1B1]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTCCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCTTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

46.835

86.813

0.407
  comGC Staphylococcus aureus N315

46.835

86.813

0.407
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396

Multiple sequence alignment