Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FSA40_RS09305 Genome accession   NZ_CP044493
Coordinates   1831780..1832721 (-) Length   313 a.a.
NCBI ID   WP_151416444.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1826780..1837721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS09265 (FSA40_1861) - 1826789..1827988 (-) 1200 WP_002263443.1 acetate kinase -
  FSA40_RS09270 (FSA40_1862) comYH 1828047..1829000 (-) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  FSA40_RS09275 (FSA40_1863) comYG 1829055..1829444 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  FSA40_RS09280 (FSA40_1864) comYF 1829422..1829856 (-) 435 WP_151416443.1 competence type IV pilus minor pilin ComGF Machinery gene
  FSA40_RS09285 (FSA40_1865) comYE 1829843..1830136 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  FSA40_RS09290 (FSA40_1866) comYD 1830108..1830512 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  FSA40_RS09295 (FSA40_1867) comYC 1830499..1830813 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  FSA40_RS09300 (FSA40_1868) comYB 1830813..1831844 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  FSA40_RS09305 (FSA40_1869) comYA 1831780..1832721 (-) 942 WP_151416444.1 competence type IV pilus ATPase ComGA Machinery gene
  FSA40_RS09310 (FSA40_1870) - 1832851..1833234 (-) 384 WP_002263434.1 DUF1033 family protein -
  FSA40_RS09315 (FSA40_1871) rpoC 1833362..1836991 (-) 3630 WP_002263433.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35666.09 Da        Isoelectric Point: 9.1733

>NTDB_id=390402 FSA40_RS09305 WP_151416444.1 1831780..1832721(-) (comYA) [Streptococcus mutans strain MD]
MVQKLGRKIIAKAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSMDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFGTK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=390402 FSA40_RS09305 WP_151416444.1 1831780..1832721(-) (comYA) [Streptococcus mutans strain MD]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCAAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGCGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTATGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCAGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGGGACCAAA
CAGGTAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGCATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

99.361

100

0.994
  comYA Streptococcus mutans UA140

99.042

100

0.99
  comYA Streptococcus gordonii str. Challis substr. CH1

67.093

100

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.026

99.681

0.658
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

99.361

0.655
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.361

0.524

Multiple sequence alignment