Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FSA40_RS09300 Genome accession   NZ_CP044493
Coordinates   1830813..1831844 (-) Length   343 a.a.
NCBI ID   WP_255262721.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1825813..1836844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS09260 (FSA40_1860) - 1825991..1826236 (-) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  FSA40_RS09265 (FSA40_1861) - 1826789..1827988 (-) 1200 WP_002263443.1 acetate kinase -
  FSA40_RS09270 (FSA40_1862) comYH 1828047..1829000 (-) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  FSA40_RS09275 (FSA40_1863) comYG 1829055..1829444 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  FSA40_RS09280 (FSA40_1864) comYF 1829422..1829856 (-) 435 WP_151416443.1 competence type IV pilus minor pilin ComGF Machinery gene
  FSA40_RS09285 (FSA40_1865) comYE 1829843..1830136 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  FSA40_RS09290 (FSA40_1866) comYD 1830108..1830512 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  FSA40_RS09295 (FSA40_1867) comYC 1830499..1830813 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  FSA40_RS09300 (FSA40_1868) comYB 1830813..1831844 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  FSA40_RS09305 (FSA40_1869) comYA 1831780..1832721 (-) 942 WP_151416444.1 competence type IV pilus ATPase ComGA Machinery gene
  FSA40_RS09310 (FSA40_1870) - 1832851..1833234 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39844.46 Da        Isoelectric Point: 9.5151

>NTDB_id=390401 FSA40_RS09300 WP_255262721.1 1830813..1831844(-) (comYB) [Streptococcus mutans strain MD]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=390401 FSA40_RS09300 WP_255262721.1 1830813..1831844(-) (comYB) [Streptococcus mutans strain MD]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTAAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

100

100

1
  comYB Streptococcus mutans UA140

99.417

100

0.994
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment