Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | FHO10_RS05895 | Genome accession | NZ_CP040898 |
| Coordinates | 1139126..1139401 (+) | Length | 91 a.a. |
| NCBI ID | WP_002356991.1 | Uniprot ID | A0A1B4XPV0 |
| Organism | Enterococcus faecalis strain HA-1 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1135586..1192294 | 1139126..1139401 | within | 0 |
Gene organization within MGE regions
Location: 1135586..1192294
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FHO10_RS05880 (FHO10_05885) | - | 1135586..1136914 (+) | 1329 | WP_002360022.1 | APC family permease | - |
| FHO10_RS05885 (FHO10_05890) | comGA | 1137155..1138123 (+) | 969 | WP_002364362.1 | competence type IV pilus ATPase ComGA | - |
| FHO10_RS05890 (FHO10_05895) | comGB | 1138080..1139126 (+) | 1047 | WP_002369171.1 | competence type IV pilus assembly protein ComGB | - |
| FHO10_RS05895 (FHO10_05900) | comGC/cglC | 1139126..1139401 (+) | 276 | WP_002356991.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| FHO10_RS05900 (FHO10_05905) | comGD | 1139398..1139841 (+) | 444 | WP_116491816.1 | competence type IV pilus minor pilin ComGD | - |
| FHO10_RS05905 (FHO10_05910) | - | 1139869..1141017 (-) | 1149 | WP_116491852.1 | site-specific integrase | - |
| FHO10_RS05910 (FHO10_05915) | - | 1141092..1141421 (-) | 330 | WP_002369911.1 | hypothetical protein | - |
| FHO10_RS05915 (FHO10_05920) | - | 1141436..1142200 (-) | 765 | WP_229077509.1 | LysM domain-containing protein | - |
| FHO10_RS05920 (FHO10_05925) | - | 1142318..1142965 (-) | 648 | WP_002372050.1 | ImmA/IrrE family metallo-endopeptidase | - |
| FHO10_RS05925 (FHO10_05930) | - | 1142970..1143311 (-) | 342 | WP_002396615.1 | helix-turn-helix domain-containing protein | - |
| FHO10_RS05935 (FHO10_05940) | - | 1143604..1143795 (+) | 192 | WP_002356998.1 | hypothetical protein | - |
| FHO10_RS05940 (FHO10_05945) | - | 1143801..1144118 (+) | 318 | WP_002356999.1 | hypothetical protein | - |
| FHO10_RS05945 (FHO10_05950) | - | 1144157..1144870 (+) | 714 | WP_116491850.1 | Rha family transcriptional regulator | - |
| FHO10_RS05950 (FHO10_05955) | - | 1144881..1145066 (+) | 186 | WP_099704312.1 | hypothetical protein | - |
| FHO10_RS05955 (FHO10_05960) | - | 1145077..1145301 (+) | 225 | WP_139926611.1 | hypothetical protein | - |
| FHO10_RS05960 (FHO10_05965) | - | 1145345..1145752 (+) | 408 | WP_002363338.1 | hypothetical protein | - |
| FHO10_RS05965 (FHO10_05970) | - | 1145765..1146508 (+) | 744 | WP_002368200.1 | hypothetical protein | - |
| FHO10_RS05970 (FHO10_05975) | - | 1146581..1146904 (+) | 324 | WP_002368201.1 | hypothetical protein | - |
| FHO10_RS05980 (FHO10_05985) | - | 1147084..1147329 (+) | 246 | WP_116491848.1 | hypothetical protein | - |
| FHO10_RS05985 (FHO10_05990) | - | 1147322..1147999 (+) | 678 | WP_116491847.1 | ERF family protein | - |
| FHO10_RS05990 (FHO10_05995) | - | 1147984..1148922 (+) | 939 | WP_116491846.1 | DUF1351 domain-containing protein | - |
| FHO10_RS05995 (FHO10_06000) | - | 1148919..1149599 (+) | 681 | WP_116491845.1 | putative HNHc nuclease | - |
| FHO10_RS06000 (FHO10_06005) | - | 1149603..1150556 (+) | 954 | WP_116491844.1 | phage replisome organizer N-terminal domain-containing protein | - |
| FHO10_RS06005 (FHO10_06010) | - | 1150553..1150981 (+) | 429 | WP_164549300.1 | RusA family crossover junction endodeoxyribonuclease | - |
| FHO10_RS06015 (FHO10_06020) | - | 1151292..1152026 (+) | 735 | WP_249455863.1 | N-6 DNA methylase | - |
| FHO10_RS06020 (FHO10_06025) | - | 1152176..1152529 (+) | 354 | WP_002415427.1 | hypothetical protein | - |
| FHO10_RS06025 (FHO10_06030) | - | 1152526..1152774 (+) | 249 | WP_002415426.1 | hypothetical protein | - |
| FHO10_RS06030 (FHO10_06035) | - | 1152786..1153370 (+) | 585 | WP_010711679.1 | DUF3850 domain-containing protein | - |
| FHO10_RS06035 (FHO10_06040) | - | 1153384..1153590 (+) | 207 | WP_116491842.1 | hypothetical protein | - |
| FHO10_RS06040 (FHO10_06045) | - | 1153964..1154380 (+) | 417 | WP_116491841.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| FHO10_RS06055 (FHO10_06060) | - | 1155221..1155451 (+) | 231 | WP_114232998.1 | hypothetical protein | - |
| FHO10_RS06060 (FHO10_06065) | - | 1155482..1155943 (+) | 462 | WP_002399680.1 | helix-turn-helix domain-containing protein | - |
| FHO10_RS06065 (FHO10_06070) | terL | 1155936..1157324 (+) | 1389 | WP_164549303.1 | phage terminase large subunit | - |
| FHO10_RS06070 (FHO10_06075) | - | 1157336..1158808 (+) | 1473 | WP_116491840.1 | phage portal protein | - |
| FHO10_RS06075 (FHO10_06080) | - | 1158786..1160687 (+) | 1902 | WP_116491839.1 | head protein | - |
| FHO10_RS06080 (FHO10_06085) | - | 1160688..1160918 (+) | 231 | WP_002380437.1 | hypothetical protein | - |
| FHO10_RS06085 (FHO10_06090) | - | 1160975..1161295 (+) | 321 | WP_116491838.1 | hypothetical protein | - |
| FHO10_RS06090 (FHO10_06095) | - | 1161514..1162137 (+) | 624 | WP_010706493.1 | DUF4355 domain-containing protein | - |
| FHO10_RS06095 (FHO10_06100) | - | 1162151..1163038 (+) | 888 | WP_002387280.1 | DUF5309 domain-containing protein | - |
| FHO10_RS06100 (FHO10_06105) | - | 1163067..1163249 (+) | 183 | WP_002387281.1 | hypothetical protein | - |
| FHO10_RS06105 (FHO10_06110) | - | 1163263..1163607 (+) | 345 | WP_002387282.1 | hypothetical protein | - |
| FHO10_RS06110 (FHO10_06115) | - | 1163604..1163978 (+) | 375 | WP_002387285.1 | hypothetical protein | - |
| FHO10_RS06115 (FHO10_06120) | - | 1163971..1164369 (+) | 399 | WP_002357036.1 | HK97 gp10 family phage protein | - |
| FHO10_RS06120 (FHO10_06125) | - | 1164372..1164746 (+) | 375 | WP_116491837.1 | DUF6838 family protein | - |
| FHO10_RS06125 (FHO10_06130) | - | 1164747..1165595 (+) | 849 | WP_002387287.1 | major tail protein | - |
| FHO10_RS06130 (FHO10_06135) | gpG | 1165647..1166023 (+) | 377 | Protein_1049 | phage tail assembly chaperone G | - |
| FHO10_RS06135 (FHO10_06140) | - | 1166243..1169140 (+) | 2898 | WP_164549302.1 | tape measure protein | - |
| FHO10_RS06140 (FHO10_06145) | - | 1169130..1169864 (+) | 735 | WP_104670712.1 | phage tail protein | - |
| FHO10_RS06145 (FHO10_06150) | - | 1169846..1172653 (+) | 2808 | WP_164549299.1 | phage tail spike protein | - |
| FHO10_RS06150 (FHO10_06155) | - | 1172672..1173553 (+) | 882 | WP_116491834.1 | phage baseplate upper protein | - |
| FHO10_RS06155 (FHO10_06160) | - | 1173546..1174142 (+) | 597 | WP_116491833.1 | hypothetical protein | - |
| FHO10_RS06160 (FHO10_06165) | - | 1174139..1174417 (+) | 279 | WP_116491832.1 | hypothetical protein | - |
| FHO10_RS06165 (FHO10_06170) | - | 1174417..1174908 (+) | 492 | WP_010711694.1 | hypothetical protein | - |
| FHO10_RS06170 (FHO10_06175) | - | 1174922..1175242 (+) | 321 | WP_002388445.1 | hypothetical protein | - |
| FHO10_RS06175 (FHO10_06180) | - | 1175244..1175399 (+) | 156 | WP_002364192.1 | XkdX family protein | - |
| FHO10_RS06180 (FHO10_06185) | - | 1175427..1175648 (+) | 222 | WP_002397443.1 | hypothetical protein | - |
| FHO10_RS06185 (FHO10_06190) | - | 1175645..1175851 (+) | 207 | WP_114232969.1 | phage holin | - |
| FHO10_RS06190 (FHO10_06195) | - | 1175854..1177155 (+) | 1302 | WP_114232968.1 | LysM peptidoglycan-binding domain-containing protein | - |
| FHO10_RS06195 (FHO10_06200) | - | 1177792..1178601 (+) | 810 | WP_159162083.1 | DUF3800 domain-containing protein | - |
| FHO10_RS06205 (FHO10_06210) | hemH | 1178923..1179864 (+) | 942 | WP_116491831.1 | ferrochelatase | - |
| FHO10_RS15375 (FHO10_06215) | - | 1180162..1180287 (-) | 126 | WP_002364184.1 | hypothetical protein | - |
| FHO10_RS06215 (FHO10_06220) | - | 1180621..1180992 (+) | 372 | WP_171025395.1 | type II secretion system protein | - |
| FHO10_RS06220 (FHO10_06225) | comGF | 1180982..1181416 (+) | 435 | WP_002378441.1 | competence type IV pilus minor pilin ComGF | - |
| FHO10_RS06225 (FHO10_06230) | comGG | 1181416..1181769 (+) | 354 | WP_002362054.1 | competence type IV pilus minor pilin ComGG | - |
| FHO10_RS06230 (FHO10_06235) | - | 1181898..1182905 (+) | 1008 | WP_002357063.1 | class I SAM-dependent methyltransferase | - |
| FHO10_RS06235 (FHO10_06240) | - | 1182930..1184117 (+) | 1188 | WP_002357064.1 | acetate/propionate family kinase | - |
| FHO10_RS06240 (FHO10_06245) | - | 1184229..1184702 (-) | 474 | WP_002357065.1 | universal stress protein | - |
| FHO10_RS06255 (FHO10_06260) | - | 1185018..1185350 (-) | 333 | WP_002357068.1 | hypothetical protein | - |
| FHO10_RS06265 (FHO10_06270) | - | 1185624..1186901 (-) | 1278 | WP_002360030.1 | replication-associated recombination protein A | - |
| FHO10_RS06270 (FHO10_06275) | - | 1187030..1187707 (+) | 678 | WP_002364174.1 | DNA-3-methyladenine glycosylase | - |
| FHO10_RS06275 (FHO10_06280) | - | 1187664..1188149 (+) | 486 | WP_002388170.1 | DUF3013 family protein | - |
| FHO10_RS06280 (FHO10_06285) | prmA | 1188165..1189112 (+) | 948 | WP_002371999.1 | 50S ribosomal protein L11 methyltransferase | - |
| FHO10_RS06285 (FHO10_06290) | - | 1189114..1189866 (+) | 753 | WP_002378439.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
| FHO10_RS06290 (FHO10_06295) | - | 1190081..1192294 (+) | 2214 | WP_002357079.1 | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | - |
Sequence
Protein
Download Length: 91 a.a. Molecular weight: 10464.41 Da Isoelectric Point: 9.3192
>NTDB_id=368099 FHO10_RS05895 WP_002356991.1 1139126..1139401(+) (comGC/cglC) [Enterococcus faecalis strain HA-1]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ
Nucleotide
Download Length: 276 bp
>NTDB_id=368099 FHO10_RS05895 WP_002356991.1 1139126..1139401(+) (comGC/cglC) [Enterococcus faecalis strain HA-1]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus pneumoniae Rx1 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae D39 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae R6 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
63.095 |
92.308 |
0.582 |
| comGC/cglC | Streptococcus mitis NCTC 12261 |
61.905 |
92.308 |
0.571 |
| comGC/cglC | Streptococcus mitis SK321 |
61.176 |
93.407 |
0.571 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
58.14 |
94.505 |
0.549 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
56.322 |
95.604 |
0.538 |
| comYC | Streptococcus suis isolate S10 |
52.326 |
94.505 |
0.495 |
| comYC | Streptococcus mutans UA159 |
57.692 |
85.714 |
0.495 |
| comYC | Streptococcus mutans UA140 |
57.692 |
85.714 |
0.495 |
| comGC | Latilactobacillus sakei subsp. sakei 23K |
46.154 |
100 |
0.462 |
| comGC | Staphylococcus aureus MW2 |
46.835 |
86.813 |
0.407 |
| comGC | Staphylococcus aureus N315 |
46.835 |
86.813 |
0.407 |
| comGC | Bacillus subtilis subsp. subtilis str. 168 |
48.649 |
81.319 |
0.396 |