Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMUNN2025_RS09395 Genome accession   NC_013928
Coordinates   1933566..1934822 (-) Length   418 a.a.
NCBI ID   WP_002277468.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1928566..1939822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS09355 (SmuNN2025_1817) - 1928758..1929057 (-) 300 WP_002277471.1 DUF1292 domain-containing protein -
  SMUNN2025_RS09360 (SmuNN2025_1818) ruvX 1929138..1929557 (-) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  SMUNN2025_RS09365 (SmuNN2025_1819) - 1929554..1929823 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUNN2025_RS09370 (SmuNN2025_1820) brsR 1929991..1930425 (+) 435 WP_012997971.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUNN2025_RS09375 (SmuNN2025_1821) brsM 1930438..1930884 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUNN2025_RS10230 - 1930875..1931075 (-) 201 Protein_1816 hypothetical protein -
  SMUNN2025_RS09380 (SmuNN2025_1822) - 1931216..1931641 (-) 426 WP_002266116.1 hypothetical protein -
  SMUNN2025_RS09385 (SmuNN2025_1823) spx 1931892..1932290 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUNN2025_RS09390 (SmuNN2025_1824) recA 1932375..1933526 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUNN2025_RS09395 (SmuNN2025_1825) cinA 1933566..1934822 (-) 1257 WP_002277468.1 competence/damage-inducible protein A Machinery gene
  SMUNN2025_RS09400 (SmuNN2025_1826) - 1934971..1935531 (-) 561 WP_002283270.1 DNA-3-methyladenine glycosylase I -
  SMUNN2025_RS09405 (SmuNN2025_1827) ruvA 1935613..1936206 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA -
  SMUNN2025_RS09410 (SmuNN2025_1828) mutL 1936391..1938346 (-) 1956 WP_002287711.1 DNA mismatch repair endonuclease MutL -
  SMUNN2025_RS10235 - 1938571..1938849 (+) 279 Protein_1824 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45705.47 Da        Isoelectric Point: 6.0193

>NTDB_id=36622 SMUNN2025_RS09395 WP_002277468.1 1933566..1934822(-) (cinA) [Streptococcus mutans NN2025]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKT
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAISLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=36622 SMUNN2025_RS09395 WP_002277468.1 1933566..1934822(-) (cinA) [Streptococcus mutans NN2025]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATTGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGACA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTATTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.761

100

0.998
  cinA Streptococcus mitis SK321

72.488

100

0.725
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.813

100

0.708
  cinA Streptococcus pneumoniae Rx1

70.574

100

0.706
  cinA Streptococcus pneumoniae R6

70.574

100

0.706
  cinA Streptococcus pneumoniae D39

70.335

100

0.703
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.247

98.804

0.457

Multiple sequence alignment