Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsM   Type   Regulator
Locus tag   SMUNN2025_RS09375 Genome accession   NC_013928
Coordinates   1930438..1930884 (+) Length   148 a.a.
NCBI ID   WP_002262388.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   repress competence development; negative regulate BrsR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1925438..1935884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS09345 (SmuNN2025_1816) - 1926953..1928524 (-) 1572 WP_002264553.1 membrane protein -
  SMUNN2025_RS09355 (SmuNN2025_1817) - 1928758..1929057 (-) 300 WP_002277471.1 DUF1292 domain-containing protein -
  SMUNN2025_RS09360 (SmuNN2025_1818) ruvX 1929138..1929557 (-) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  SMUNN2025_RS09365 (SmuNN2025_1819) - 1929554..1929823 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUNN2025_RS09370 (SmuNN2025_1820) brsR 1929991..1930425 (+) 435 WP_012997971.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUNN2025_RS09375 (SmuNN2025_1821) brsM 1930438..1930884 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUNN2025_RS10230 - 1930875..1931075 (-) 201 Protein_1816 hypothetical protein -
  SMUNN2025_RS09380 (SmuNN2025_1822) - 1931216..1931641 (-) 426 WP_002266116.1 hypothetical protein -
  SMUNN2025_RS09385 (SmuNN2025_1823) spx 1931892..1932290 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUNN2025_RS09390 (SmuNN2025_1824) recA 1932375..1933526 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUNN2025_RS09395 (SmuNN2025_1825) cinA 1933566..1934822 (-) 1257 WP_002277468.1 competence/damage-inducible protein A Machinery gene
  SMUNN2025_RS09400 (SmuNN2025_1826) - 1934971..1935531 (-) 561 WP_002283270.1 DNA-3-methyladenine glycosylase I -

Sequence

Protein


Download         Length: 148 a.a.        Molecular weight: 17106.61 Da        Isoelectric Point: 10.1992

>NTDB_id=36620 SMUNN2025_RS09375 WP_002262388.1 1930438..1930884(+) (brsM) [Streptococcus mutans NN2025]
MKILKQIITYSFIGIGIGSLMNYFIAIFFFPNSNPLGVPSFVQLFSSVSQATAVQLFIFALLGVLQGFASSLFKNEKLSL
LTTSLIHYLFIVLPLLLAGSYLHWFYMTRKYFVFSFLLVSIIYILIYLFCYFENKKNIQKINKKLHQI

Nucleotide


Download         Length: 447 bp        

>NTDB_id=36620 SMUNN2025_RS09375 WP_002262388.1 1930438..1930884(+) (brsM) [Streptococcus mutans NN2025]
ATGAAAATACTCAAACAGATTATTACTTACAGTTTTATTGGTATAGGAATCGGTTCTTTAATGAATTATTTCATAGCCAT
CTTCTTTTTCCCAAATAGTAATCCACTTGGTGTCCCAAGTTTTGTTCAACTTTTTTCATCAGTTTCACAGGCAACAGCAG
TCCAACTTTTCATTTTTGCTCTTCTAGGCGTTTTACAAGGATTTGCTAGCAGCCTCTTTAAAAATGAAAAACTCAGTCTA
CTAACCACAAGCTTGATTCACTATTTATTCATTGTCCTACCACTTCTCTTAGCCGGATCTTATTTACACTGGTTTTACAT
GACTCGGAAATATTTCGTTTTTTCTTTCCTTTTGGTTTCTATTATTTATATCCTCATTTACTTATTCTGCTATTTTGAAA
ATAAAAAAAACATTCAAAAAATCAATAAGAAGCTGCATCAAATATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF3021) (DUF3021)

(5-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsM Streptococcus mutans UA159

100

100

1

Multiple sequence alignment