Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SMUNN2025_RS09370 Genome accession   NC_013928
Coordinates   1929991..1930425 (+) Length   144 a.a.
NCBI ID   WP_012997971.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1924991..1935425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS09345 (SmuNN2025_1816) - 1926953..1928524 (-) 1572 WP_002264553.1 membrane protein -
  SMUNN2025_RS09355 (SmuNN2025_1817) - 1928758..1929057 (-) 300 WP_002277471.1 DUF1292 domain-containing protein -
  SMUNN2025_RS09360 (SmuNN2025_1818) ruvX 1929138..1929557 (-) 420 WP_002277470.1 Holliday junction resolvase RuvX -
  SMUNN2025_RS09365 (SmuNN2025_1819) - 1929554..1929823 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUNN2025_RS09370 (SmuNN2025_1820) brsR 1929991..1930425 (+) 435 WP_012997971.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUNN2025_RS09375 (SmuNN2025_1821) brsM 1930438..1930884 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUNN2025_RS10230 - 1930875..1931075 (-) 201 Protein_1816 hypothetical protein -
  SMUNN2025_RS09380 (SmuNN2025_1822) - 1931216..1931641 (-) 426 WP_002266116.1 hypothetical protein -
  SMUNN2025_RS09385 (SmuNN2025_1823) spx 1931892..1932290 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUNN2025_RS09390 (SmuNN2025_1824) recA 1932375..1933526 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUNN2025_RS09395 (SmuNN2025_1825) cinA 1933566..1934822 (-) 1257 WP_002277468.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 17240.28 Da        Isoelectric Point: 10.7353

>NTDB_id=36619 SMUNN2025_RS09370 WP_012997971.1 1929991..1930425(+) (brsR) [Streptococcus mutans NN2025]
MKLKIIKDSNFKEPLLQIYTRHIDKQTQRVIDFIQQRPNIVYGYKNKRLEFIPLEKVIRIFTENKQVLIQTSTDIYLAKQ
RLYFFEQELGTPFIRISQGEIINIKYIKQLNLTIRGSIEVTFKNGTVSFVARRSLKRFKEQLNL

Nucleotide


Download         Length: 435 bp        

>NTDB_id=36619 SMUNN2025_RS09370 WP_012997971.1 1929991..1930425(+) (brsR) [Streptococcus mutans NN2025]
ATGAAATTAAAAATTATCAAGGATTCAAACTTTAAGGAACCCTTACTCCAAATCTATACACGTCATATTGATAAACAAAC
GCAAAGAGTGATTGATTTTATTCAACAAAGACCTAATATCGTTTATGGTTACAAAAATAAACGCTTAGAGTTTATCCCAC
TAGAAAAAGTGATTCGTATTTTCACGGAAAACAAACAGGTCTTAATTCAAACATCAACCGATATCTATTTAGCTAAACAA
AGACTCTACTTTTTTGAGCAAGAATTAGGAACACCTTTTATTCGTATCTCCCAAGGTGAAATCATCAATATCAAATATAT
TAAACAATTAAATTTAACCATCCGAGGCAGCATTGAAGTGACTTTCAAAAATGGAACAGTCAGTTTCGTGGCTAGGCGAA
GTTTGAAACGCTTCAAAGAACAATTAAATCTTTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(48-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

97.222

100

0.972

Multiple sequence alignment