Detailed information NTG0345894

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EXW33_RS18260
• Genome accession: NZ_CP036014
• Coordinates: 3547802..3550402 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365397.1
• Uniprot ID: A0A2B6H9B6
• Organism: Bacillus toyonensis strain BPN45/4
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3542802..3555402

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW33_RS18220 (EXW33_18645)	-	3542911..3543496 (+)	586	Protein_3528	hypothetical protein	-
EXW33_RS18225 (EXW33_18650)	prsA	3543565..3544422 (-)	858	WP_001214219.1	peptidylprolyl isomerase PrsA	-
EXW33_RS18230 (EXW33_18655)	-	3544552..3544683 (-)	132	WP_001120851.1	DUF3941 domain-containing protein	-
EXW33_RS18235 (EXW33_18660)	-	3544784..3545641 (+)	858	WP_000364440.1	YitT family protein	-
EXW33_RS18240 (EXW33_18665)	-	3545667..3545864 (-)	198	WP_000527396.1	DUF3813 domain-containing protein	-
EXW33_RS18245 (EXW33_18670)	-	3545865..3546005 (-)	141	WP_000516816.1	hypothetical protein	-
EXW33_RS18250 (EXW33_18675)	-	3546110..3546919 (-)	810	WP_000043171.1	Cof-type HAD-IIB family hydrolase	-
EXW33_RS18255 (EXW33_18680)	-	3547412..3547591 (+)	180	WP_002093816.1	YjzC family protein	-
EXW33_RS18260 (EXW33_18685)	clpC	3547802..3550402 (+)	2601	WP_000365397.1	ATP-dependent chaperone ClpB	Regulator
EXW33_RS18265 (EXW33_18690)	-	3550439..3550621 (-)	183	WP_001211112.1	YjzD family protein	-
EXW33_RS18270 (EXW33_18695)	-	3550778..3551512 (+)	735	WP_000028709.1	hypothetical protein	-
EXW33_RS18275 (EXW33_18700)	-	3551542..3552420 (+)	879	WP_000486172.1	NAD(P)-dependent oxidoreductase	-
EXW33_RS18280 (EXW33_18705)	comZ	3552485..3552661 (+)	177	WP_001003338.1	ComZ family protein	Regulator
EXW33_RS18285 (EXW33_18710)	fabH	3552906..3553838 (+)	933	WP_001100553.1	beta-ketoacyl-ACP synthase III	-
EXW33_RS18290 (EXW33_18715)	fabF	3553869..3555107 (+)	1239	WP_000412641.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97611.62 Da
• Isoelectric Point: 5.1950

>NTDB_id=345894 EXW33_RS18260 WP_000365397.1 3547802..3550402(+) (clpC) [Bacillus toyonensis strain BPN45/4]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQDVENVIKKKPSVTGSGAE
VGKLYITSNLQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINHLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMSAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDSAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=345894 EXW33_RS18260 WP_000365397.1 3547802..3550402(+) (clpC) [Bacillus toyonensis strain BPN45/4]
ATGGACTTAAATCAAATGACAACGAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAGGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTGAAACAAGATGTAGAAAATGTAATTAAAAAGAAACCTTCTGTAACGGGAAGCGGAGCAGAA
GTTGGGAAATTGTATATAACAAGCAATCTGCAGCAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATCAATCATTTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGCCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGACGAGA
TAGTGAAATTCGCCGCGTTATTCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGATTAGCACAGCGTATCGTGAAAAAAGATGTACCAGAAGGGTTAAAAGATAGAACAATC
TTTGCATTAGATATGAGTGCACTTGTAGCCGGAGCAAAATTCCGTGGTGAATTTGAAGAGCGCCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGCCGTATTTTATTATTCATTGATGAACTTCATACAATCGTCGGTGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGGAATATGTTAAAACCGATGCTTGCTCGTGGTGAACTGCATTGTATCGGGGCAACGACATTAGAT
GAATATCGTAAATATATTGAGAAAGACCCAGCGTTAGAAAGACGTTTCCAACAAGTATTAGCAGAGGAACCGACTGTTGA
AGATACAATCTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCTGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCGGATAAAGCAATTGACCTTGTTGACGAAGCG
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGTATTATGCAGCTGGAAAT
TGAAGAAGCCGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGTCTGAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
AAAAATTCCTGCAATTGAAAAAGAATTAAAAGAAGCGGAAGAAATGAGCGCACATAATAAACAAGAAAATCGTTTATTAC
GCGAGGAAGTCAGTGAAGAAGAAATTGCTGATATCGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAGGGT
GAACGTGAGAAATTACTACGCTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGTTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATTTTCTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATCGACATG
TCTGAGTACATGGAGAAACATGCTGTGTCACGCTTAATTGGTGCACCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACGGAAGCAGTAAGACGTAAACCGTATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCGCATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGCAGATGGTTCCATTAAAGAGGAATCAAGAGA
ACTTGTCATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAATCGTGTCGATGAAATTATTTTATTCAAGCCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACG
GTAGAATTAACGGATTCTGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCGAGAGAATTAATTGCAGGCACAATTACGGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTTGTTCATGTGAAATGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A2B6H9B6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	46.704	82.333	0.385