Detailed information NTG0345230

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: GFB63_RS05405
• Genome accession: NZ_CP045596
• Coordinates: 1043935..1046088 (-)
• Length: 717 a.a.
• NCBI ID: WP_193838175.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1038935..1051088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS05380 (GFB63_05535)	-	1039826..1040167 (+)	342	WP_024404826.1	LytTR family DNA-binding domain-containing protein	-
GFB63_RS05385 (GFB63_05540)	comE/blpR	1040169..1040909 (+)	741	WP_193838172.1	response regulator transcription factor	Regulator
GFB63_RS05390 (GFB63_05545)	-	1040920..1042260 (+)	1341	WP_193838173.1	sensor histidine kinase	-
GFB63_RS05395 (GFB63_05550)	-	1042308..1042463 (-)	156	WP_096811960.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GFB63_RS05400 (GFB63_05555)	comB	1042562..1043923 (-)	1362	WP_193838174.1	bacteriocin secretion accessory protein	Regulator
GFB63_RS05405 (GFB63_05560)	comA/nlmT	1043935..1046088 (-)	2154	WP_193838175.1	peptide cleavage/export ABC transporter	Regulator
GFB63_RS05410 (GFB63_05565)	-	1046386..1046643 (+)	258	WP_039671027.1	Blp family class II bacteriocin	-
GFB63_RS05415 (GFB63_05570)	-	1046660..1046854 (+)	195	WP_039671026.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
GFB63_RS05420 (GFB63_05575)	-	1047456..1048806 (+)	1351	Protein_1026	IS3 family transposase	-
GFB63_RS05425 (GFB63_05580)	-	1049230..1050255 (+)	1026	WP_193838176.1	thioredoxin fold domain-containing protein	-
GFB63_RS05430 (GFB63_05585)	-	1050259..1050954 (+)	696	WP_111679181.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80557.53 Da
• Isoelectric Point: 7.1817

>NTDB_id=345230 GFB63_RS05405 WP_193838175.1 1043935..1046088(-) (comA/nlmT) [Streptococcus thermophilus strain TK-P3A]
MTAYKRTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAKEMGFETRAIQADMSLFDMDDV
PYPFIVHVNKEGKLQHYYMVYHNKKDHLIIGDPDPTVKVTKMTKERFASEWTGVAIFLAPEPSFKPHKDKKNGLMSFLPL
IFRQRALIFYIVLASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGGVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQTTLKQGAQL
ILNIVILWFGAQLVMNGHISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESELSNNQTLTDSQFL
TGDIRFEDLSYKYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKLIDKKTLRQHI
NYLPQQAYIFSGSILENLTLGANQLISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMADKTIIFVAHRLSISERTNQVIVLDQGKVIETGSHHELMTKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=345230 GFB63_RS05405 WP_193838175.1 1043935..1046088(-) (comA/nlmT) [Streptococcus thermophilus strain TK-P3A]
ATGACAGCTTACAAACGAACTTTTGTTCCTCAAATCGATGCCAGAGACTGTGGTGTGGCTGCTTTAGCCTCTATTGCCAA
GTTTTATGGTTCTGATTATTCCCTAGCTCATTTGAGAGAATTGGCCAAAACCAATAAGGAAGGAACGACCGCTCTTGGTA
TCGTCAAAGCAGCCAAGGAGATGGGCTTTGAAACTAGAGCCATCCAGGCTGACATGAGCCTCTTTGATATGGATGACGTT
CCCTATCCCTTCATCGTTCACGTCAATAAAGAAGGCAAACTGCAACACTACTATATGGTCTATCACAACAAAAAAGACCA
CCTCATCATTGGTGATCCTGACCCTACGGTCAAAGTCACCAAGATGACCAAGGAGCGGTTTGCTTCTGAATGGACAGGCG
TTGCTATCTTTCTGGCTCCAGAACCCAGCTTTAAGCCTCACAAAGATAAAAAGAACGGCCTGATGAGCTTTCTCCCTCTT
ATTTTCAGGCAACGTGCGCTTATCTTTTATATCGTCTTGGCTAGCCTTTTGGTGACACTTATCAATATTGGTGGTTCTTA
CTACCTGCAAGGGATTTTGGATGAATACATTCCTAATCAAATGAAGTCAACCTTGGGGATTATCTCCATCGGCCTGATTA
TCACCTACATCCTCCAGCAGATGATGAGTTTCTCACGAGATTACCTTTTGACTGTGCTCAGCCAGCGGCTAAGCATTGAT
GTGATTCTTTCCTATATCCGTCATATCTTTGAACTGCCCATGTCCTTTTTTGCGACACGGCGGACTGGTGAGGTTATCTC
TCGCTTTACAGATGCCAATTCAATCATTGATGCCCTGGCATCGACCATTTTGTCACTCTTCCTTGATGTCTCTATTTTAA
CCATCGTCGGTGGTGTGCTTTTGGTACAAAACACCAACCTCTTCCTGCTCTCCTTGATTTCAGTTCCCATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCGTTTGAGAAGATGAATAACGATGTGATGCAGAGCAATTCCATGGTCAGCTCTGCCAT
TATCGAAGACATCAACGGCATTGAAACCATCAAATCCTTGACCAGTGAAGAAAGCCGCTACCAGAAGATTGATAGCGAGT
TCGTAGATTACCTGGACAAATCCTTCAAACTCAGTAAATACTCTATCCTGCAAACTACCCTTAAACAGGGAGCTCAGCTC
ATTCTAAATATTGTCATCTTGTGGTTTGGGGCCCAGCTAGTCATGAACGGACACATTTCAGTTGGACAACTGATCACCTT
CAACACCCTTCTATCTTATTTTACCAATCCTTTAGAAAATATTATAAACCTCCAAACCAAGCTCCAGTCTGCCAAGGTGG
CTAACAATCGCCTGAATGAAGTCTACCTGGTTGAATCTGAACTCAGTAACAATCAGACCTTAACAGATTCACAGTTCCTG
ACTGGCGATATTCGCTTTGAAGACCTTTCCTATAAGTACGGTTTCGGACGTGACACCCTATCGGATATCAATCTGACCAT
CAAACAAGGCGATAAGGTCAGTCTAGTGGGAATTAGCGGCTCAGGAAAAACAACCTTGGCCAAGATGATTGTCAATTTCT
TTGAGCCTTACAAGGGTCGAATCACCATCAACAACAATGACCTTAAACTAATTGATAAAAAGACGCTTCGGCAACACATT
AACTACCTCCCACAACAAGCTTATATCTTCAGTGGTTCAATCTTAGAAAACTTGACTTTAGGGGCCAATCAACTGATTAG
TCAGGAAGATATTATCAGAGCTTGTGAGATCGCTGAAATTCGACAAGACATCGAGCAGATGCCTATGGGCTATCAAACAG
AATTGTCTGACGGAGCTGGCTTATCGGGTGGTCAAAAGCAACGGATTGCTTTGGCTAGGGCTCTACTGACTAAAGCCCCT
GTTCTTATTCTTGATGAAGCCACTAGCGGCCTTGATGTGCTAACGGAGAAAAAGGTCATTGATAATTTAATGGCCATGGC
AGACAAGACCATTATCTTTGTCGCACACCGCCTCAGTATTTCTGAGCGAACCAACCAAGTTATCGTTCTTGACCAAGGGA
AGGTCATTGAGACTGGTTCACATCACGAATTGATGACCAAACAAGGTTTCTACCATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.566	99.721	0.734
comA	Streptococcus mitis NCTC 12261	68.073	99.163	0.675
comA	Streptococcus mitis SK321	67.511	99.163	0.669
comA	Streptococcus pneumoniae Rx1	67.37	99.163	0.668
comA	Streptococcus pneumoniae D39	67.37	99.163	0.668
comA	Streptococcus pneumoniae R6	67.37	99.163	0.668
comA	Streptococcus pneumoniae TIGR4	67.089	99.163	0.665
comA	Streptococcus gordonii str. Challis substr. CH1	65.315	99.721	0.651