Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SALIVB_RS08595 Genome accession   NC_015760
Coordinates   1877211..1877951 (+) Length   246 a.a.
NCBI ID   WP_013991119.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1872211..1882951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS08565 (SALIVB_1786) tnpA 1872864..1873337 (-) 474 WP_013990678.1 IS200/IS605 family transposase -
  SALIVB_RS08575 (SALIVB_1787) - 1873933..1874919 (-) 987 WP_013991115.1 IS30 family transposase -
  SALIVB_RS08580 (SALIVB_1788) - 1875137..1875502 (-) 366 WP_013991116.1 hypothetical protein -
  SALIVB_RS08585 (SALIVB_1789) - 1875720..1876016 (-) 297 WP_013991117.1 bacteriocin immunity protein -
  SALIVB_RS08590 (SALIVB_1791) - 1876486..1876878 (-) 393 WP_003094909.1 hypothetical protein -
  SALIVB_RS10815 - 1876887..1876952 (-) 66 Protein_1669 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SALIVB_RS08595 (SALIVB_1793) comE/blpR 1877211..1877951 (+) 741 WP_013991119.1 response regulator transcription factor Regulator
  SALIVB_RS11050 (SALIVB_1794) comD/comD3 1878533..1879282 (+) 750 WP_013991120.1 sensor histidine kinase Regulator
  SALIVB_RS11140 (SALIVB_1795) - 1879369..1879770 (-) 402 WP_013991121.1 hypothetical protein -
  SALIVB_RS10905 (SALIVB_1796) - 1880117..1880284 (-) 168 WP_013991122.1 hypothetical protein -
  SALIVB_RS08615 (SALIVB_1799) - 1880773..1881003 (-) 231 WP_013991125.1 Blp family class II bacteriocin -
  SALIVB_RS08620 (SALIVB_1800) - 1881164..1882909 (-) 1746 WP_013991126.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28672.25 Da        Isoelectric Point: 7.9396

>NTDB_id=34236 SALIVB_RS08595 WP_013991119.1 1877211..1877951(+) (comE/blpR) [Streptococcus salivarius CCHSS3]
MEIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIEIKGEKLKGLDIAKIIREKN
PYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIHIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
KRRNLQ

Nucleotide


Download         Length: 741 bp        

>NTDB_id=34236 SALIVB_RS08595 WP_013991119.1 1877211..1877951(+) (comE/blpR) [Streptococcus salivarius CCHSS3]
TTGGAAATTTATATTTTAGAGGACAATCTCATTCAACAAGGACGACTGGAGATGGTATTGTCTCAAGAGTTAAAAAAATA
CAATAAAGACTTATCTATTGTACACACCTTTGATAAGCCTCAGCAATTTATAGAAGCGATTGATTCAACAACTTCTAACC
AGCTCTTTTTTCTTGATATCGAAATTAAGGGAGAAAAATTAAAAGGGCTCGATATTGCTAAAATCATTAGGGAAAAAAAT
CCCTACGCTACTATTATCTTTGTCACTACCCACTCAGAGTTTATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATCGATAAAAGTCTCTCTGAAATAGAATTTAGGAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GAATAGAGAATGACGAGATTTTTGATTTTCAAACACAACATACAGCTATTCACATCCCTTTAAACCAAGTTATCTATATT
GAAACTTCTCCGCAAAAGCATTATGTGATACTCCATGGTACAAACAATCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCATCGTTCGTATCTCATTAACCCTAACAACATTATAAGAATCAACAAAT
TAAAACGTGAAGTCGAAATGACTGATGGTAGTATCTGTCCTTTTTCACGTACCAAAGCTAAAATGCTGATGGATACTTTT
AAAAGAAGGAACCTTCAATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(150-239)

Response regulator receiver domain (Response_reg)

(18-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

43.59

95.122

0.415
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.8

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.8

100

0.374
  comE/comE2 Streptococcus equinus JB1

38.397

96.341

0.37
  comE/comE1 Streptococcus equinus JB1

37.815

96.748

0.366
  comE Streptococcus pneumoniae TIGR4

35.6

100

0.362
  comE Streptococcus mitis SK321

35.6

100

0.362
  comE Streptococcus mitis NCTC 12261

35.6

100

0.362
  comE Streptococcus infantis strain Atu-4

35.6

100

0.362
  comE Streptococcus pneumoniae Rx1

35.6

100

0.362
  comE Streptococcus pneumoniae D39

35.6

100

0.362
  comE Streptococcus pneumoniae R6

35.6

100

0.362

Multiple sequence alignment