Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   ETT48_RS03985 Genome accession   NZ_CP035451
Coordinates   755056..755448 (+) Length   130 a.a.
NCBI ID   WP_011017370.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm230     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 737127..782388 755056..755448 within 0


Gene organization within MGE regions


Location: 737127..782388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT48_RS03845 (ETT48_03840) - 737127..737720 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ETT48_RS03850 (ETT48_03845) rfbB 737963..739003 (+) 1041 WP_002992973.1 dTDP-glucose 4,6-dehydratase -
  ETT48_RS03855 (ETT48_03850) - 739097..740236 (-) 1140 WP_063633112.1 site-specific integrase -
  ETT48_RS03860 (ETT48_03855) - 740373..741053 (-) 681 WP_002990092.1 hypothetical protein -
  ETT48_RS03865 (ETT48_03860) - 741091..741825 (-) 735 WP_063633113.1 S24 family peptidase -
  ETT48_RS03875 (ETT48_03870) - 742184..742342 (+) 159 WP_008087431.1 hypothetical protein -
  ETT48_RS03880 (ETT48_03875) - 742441..743082 (-) 642 WP_001008979.1 hypothetical protein -
  ETT48_RS03885 (ETT48_03880) - 743227..744423 (-) 1197 WP_011017350.1 site-specific integrase -
  ETT48_RS03890 (ETT48_03885) - 744734..745474 (-) 741 WP_011017351.1 type II toxin-antitoxin system PemK/MazF family toxin -
  ETT48_RS03895 (ETT48_03890) - 745485..745877 (-) 393 WP_011017352.1 ImmA/IrrE family metallo-endopeptidase -
  ETT48_RS03900 (ETT48_03895) - 745881..746231 (-) 351 WP_011017353.1 helix-turn-helix domain-containing protein -
  ETT48_RS03905 (ETT48_03900) - 746520..746795 (+) 276 WP_011017354.1 hypothetical protein -
  ETT48_RS03910 (ETT48_03905) - 746830..747042 (+) 213 WP_063633114.1 helix-turn-helix domain-containing protein -
  ETT48_RS09505 - 747116..747250 (+) 135 WP_011017356.1 hypothetical protein -
  ETT48_RS03915 (ETT48_03910) - 747370..747870 (-) 501 WP_032464978.1 hypothetical protein -
  ETT48_RS03920 (ETT48_03915) - 747922..748641 (+) 720 WP_011017357.1 ORF6C domain-containing protein -
  ETT48_RS03925 (ETT48_03920) - 748715..748972 (+) 258 WP_011054421.1 hypothetical protein -
  ETT48_RS03930 (ETT48_03925) - 749065..749256 (+) 192 WP_011017359.1 hypothetical protein -
  ETT48_RS03935 (ETT48_03930) - 749377..749565 (+) 189 WP_032461348.1 hypothetical protein -
  ETT48_RS03940 (ETT48_03935) dnaB 749552..750892 (+) 1341 WP_011017360.1 replicative DNA helicase -
  ETT48_RS03945 (ETT48_03940) - 750885..751646 (+) 762 WP_011017361.1 conserved phage C-terminal domain-containing protein -
  ETT48_RS03950 (ETT48_03945) - 751646..752458 (+) 813 WP_023611651.1 ATP-binding protein -
  ETT48_RS03955 (ETT48_03950) - 752458..752685 (+) 228 WP_032467212.1 hypothetical protein -
  ETT48_RS09510 - 752699..752824 (+) 126 WP_257000584.1 hypothetical protein -
  ETT48_RS03960 (ETT48_03955) - 752841..753284 (+) 444 WP_011017365.1 YopX family protein -
  ETT48_RS09355 - 753281..753451 (+) 171 WP_023611649.1 hypothetical protein -
  ETT48_RS03965 (ETT48_03960) - 753448..753717 (+) 270 WP_011017366.1 hypothetical protein -
  ETT48_RS03970 (ETT48_03965) - 753719..754351 (+) 633 WP_023611652.1 N-6 DNA methylase -
  ETT48_RS03975 (ETT48_03970) - 754356..754841 (+) 486 WP_011017368.1 DUF1642 domain-containing protein -
  ETT48_RS03980 (ETT48_03975) - 754838..755059 (+) 222 WP_011017369.1 hypothetical protein -
  ETT48_RS03985 (ETT48_03980) ssbA 755056..755448 (+) 393 WP_011017370.1 single-stranded DNA-binding protein Machinery gene
  ETT48_RS03990 (ETT48_03985) - 755463..755744 (+) 282 WP_011054431.1 hypothetical protein -
  ETT48_RS03995 (ETT48_03990) - 755741..756079 (+) 339 WP_011017371.1 helix-turn-helix domain-containing protein -
  ETT48_RS04000 (ETT48_03995) - 756082..756909 (+) 828 WP_011017372.1 prohibitin family protein -
  ETT48_RS04005 (ETT48_04000) - 756924..757325 (+) 402 WP_011017373.1 hypothetical protein -
  ETT48_RS04010 (ETT48_04005) - 757485..758060 (+) 576 WP_011054435.1 site-specific integrase -
  ETT48_RS04015 (ETT48_04010) - 758214..758507 (+) 294 WP_011017375.1 hypothetical protein -
  ETT48_RS04020 (ETT48_04015) - 758565..758768 (+) 204 WP_011017376.1 hypothetical protein -
  ETT48_RS04025 (ETT48_04020) - 758794..759180 (+) 387 WP_011017377.1 hypothetical protein -
  ETT48_RS04030 (ETT48_04025) - 759173..759478 (+) 306 WP_011017378.1 HNH endonuclease -
  ETT48_RS04035 (ETT48_04030) - 759619..759936 (+) 318 WP_011017379.1 P27 family phage terminase small subunit -
  ETT48_RS04040 (ETT48_04035) - 759949..761679 (+) 1731 WP_011017380.1 terminase large subunit domain-containing protein -
  ETT48_RS04045 (ETT48_04040) - 761682..761894 (+) 213 WP_136260634.1 hypothetical protein -
  ETT48_RS04050 (ETT48_04045) - 762047..763234 (+) 1188 WP_063633115.1 phage portal protein -
  ETT48_RS04055 (ETT48_04050) - 763215..764021 (+) 807 WP_063633116.1 head maturation protease, ClpP-related -
  ETT48_RS04060 (ETT48_04055) - 764038..765171 (+) 1134 WP_063633117.1 phage major capsid protein -
  ETT48_RS09360 - 765182..765355 (+) 174 WP_165363099.1 hypothetical protein -
  ETT48_RS04065 (ETT48_04060) - 765355..765663 (+) 309 WP_063633118.1 hypothetical protein -
  ETT48_RS04070 (ETT48_04065) - 765656..766018 (+) 363 WP_063633119.1 hypothetical protein -
  ETT48_RS04075 (ETT48_04070) - 766020..766418 (+) 399 WP_011017387.1 HK97 gp10 family phage protein -
  ETT48_RS04080 (ETT48_04075) - 766411..766791 (+) 381 WP_063633120.1 hypothetical protein -
  ETT48_RS04085 (ETT48_04080) - 766803..767387 (+) 585 WP_063633121.1 major tail protein -
  ETT48_RS04090 (ETT48_04085) gpG 767480..767782 (+) 303 WP_063633122.1 phage tail assembly chaperone G -
  ETT48_RS04100 (ETT48_04095) - 768008..772108 (+) 4101 WP_063633123.1 phage tail tape measure protein -
  ETT48_RS04105 (ETT48_04100) - 772121..772891 (+) 771 WP_011017392.1 distal tail protein Dit -
  ETT48_RS04110 (ETT48_04105) - 772888..774936 (+) 2049 WP_063633124.1 phage tail spike protein -
  ETT48_RS04115 (ETT48_04110) hylP 774936..776054 (+) 1119 WP_136040268.1 hyaluronoglucosaminidase -
  ETT48_RS04120 (ETT48_04115) - 776067..777977 (+) 1911 WP_136040269.1 gp58-like family protein -
  ETT48_RS04125 (ETT48_04120) - 777991..778152 (+) 162 WP_002987333.1 hypothetical protein -
  ETT48_RS04130 (ETT48_04125) - 778155..778766 (+) 612 WP_002990014.1 DUF1366 domain-containing protein -
  ETT48_RS04135 (ETT48_04130) - 778777..779073 (+) 297 WP_002990012.1 hypothetical protein -
  ETT48_RS04140 (ETT48_04135) - 779070..779255 (+) 186 WP_002990010.1 holin -
  ETT48_RS04145 (ETT48_04140) - 779367..780701 (+) 1335 WP_063633060.1 GH25 family lysozyme -
  ETT48_RS04150 (ETT48_04145) spei 780975..781652 (+) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  ETT48_RS04155 (ETT48_04150) speh 781678..782388 (+) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -

Sequence


Protein


Download         Length: 130 a.a.        Molecular weight: 14755.61 Da        Isoelectric Point: 6.3209

>NTDB_id=342300 ETT48_RS03985 WP_011017370.1 755056..755448(+) (ssbA) [Streptococcus pyogenes strain emm230]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVIWRKSAENLSNWAKKGQLIAITGRIQTR
NYENQQGQRVYVTEVVAESFQILEKRDNTANTSSLADSMPDYGPEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=342300 ETT48_RS03985 WP_011017370.1 755056..755448(+) (ssbA) [Streptococcus pyogenes strain emm230]
ATGATCAATAACGTTGTTTTGATTGGCCGCTTAACAAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTAGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGGCAAAAAGAGGCTGACTTTATCAATTGTGTCATCT
GGCGAAAGTCTGCCGAGAATTTATCAAACTGGGCTAAAAAAGGGCAATTGATTGCAATAACAGGACGCATACAGACTCGT
AATTATGAAAACCAGCAAGGACAACGTGTCTATGTTACGGAAGTTGTCGCAGAAAGCTTCCAGATTTTGGAGAAGCGTGA
TAACACTGCAAACACAAGCAGTTTAGCTGATAGCATGCCAGACTATGGACCAGAACCAGATTTACCATTTTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

68.224

82.308

0.562

  ssb Latilactobacillus sakei subsp. sakei 23K

66.972

83.846

0.562

  ssbB Streptococcus sobrinus strain NIDR 6715-7

48.148

100

0.5

  ssbB/cilA Streptococcus pneumoniae TIGR4

44.853

100

0.469

  ssbB/cilA Streptococcus mitis NCTC 12261

44.853

100

0.469

  ssbB/cilA Streptococcus pneumoniae Rx1

44.118

100

0.462

  ssbB/cilA Streptococcus pneumoniae R6

44.118

100

0.462

  ssbB/cilA Streptococcus pneumoniae D39

44.118

100

0.462

  ssbB/cilA Streptococcus mitis SK321

43.704

100

0.454

  ssbA Streptococcus mutans UA159

43.704

100

0.454

  ssbB Bacillus subtilis subsp. subtilis str. 168

53.774

81.538

0.438

  ssbB Lactococcus lactis subsp. cremoris KW2

42.636

99.231

0.423


Multiple sequence alignment