Detailed information NTG0034181

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SALIVB_RS02340
• Genome accession: NC_015760
• Coordinates: 447627..448370 (-)
• Length: 247 a.a.
• NCBI ID: WP_002886749.1
• Uniprot ID: -
• Organism: Streptococcus salivarius CCHSS3
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 442627..453370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVB_RS02320 (SALIVB_0464)	-	443497..444156 (+)	660	WP_013990156.1	ABC transporter ATP-binding protein	-
SALIVB_RS02325 (SALIVB_0465)	-	444171..444887 (+)	717	WP_041817342.1	hypothetical protein	-
SALIVB_RS02330 (SALIVB_0467)	tnpA	445126..445590 (+)	465	WP_002883780.1	IS200/IS605 family transposase	-
SALIVB_RS02335 (SALIVB_0469)	comD/blpH	446310..447377 (-)	1068	WP_231844796.1	sensor histidine kinase	Regulator
SALIVB_RS02340 (SALIVB_0470)	comE/blpR	447627..448370 (-)	744	WP_002886749.1	response regulator transcription factor	Regulator
SALIVB_RS10965 (SALIVB_0471)	-	448870..449223 (+)	354	WP_013990160.1	hypothetical protein	-
SALIVB_RS02355 (SALIVB_0473)	tnpA	449895..450368 (+)	474	WP_013990162.1	IS200/IS605 family transposase	-
SALIVB_RS02360 (SALIVB_0474)	-	450629..451015 (+)	387	WP_013990163.1	helix-turn-helix domain-containing protein	-
SALIVB_RS02365 (SALIVB_0475)	-	451151..451843 (+)	693	WP_013990164.1	DUF6287 domain-containing protein	-
SALIVB_RS02370 (SALIVB_0476)	-	451908..452198 (+)	291	WP_002885564.1	hypothetical protein	-

Sequence

Protein

• Length: 247 a.a.
• Molecular weight: 28781.30 Da
• Isoelectric Point: 7.0440

>NTDB_id=34181 SALIVB_RS02340 WP_002886749.1 447627..448370(-) (comE/blpR) [Streptococcus salivarius CCHSS3]
MLNIFILEDDFLQQSRIETVIKDVISKKSLKCKGPEIYGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALNDEFFYERVRLAIEYTMDKLGATITQDSFTFETSMAHVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADERLYRCHRSFIVNPENILKINKEEKMAMFDNNIGCPISRTKYRGLLE
KVKSMKS

Nucleotide

• Length: 744 bp

>NTDB_id=34181 SALIVB_RS02340 WP_002886749.1 447627..448370(-) (comE/blpR) [Streptococcus salivarius CCHSS3]
TTGTTAAATATTTTTATTTTAGAAGATGATTTCTTACAACAATCACGAATAGAAACAGTTATTAAGGATGTTATTTCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTATGGAAAACCTAGCCAATTACTTGACGCAATTACCGAAAGAGGCTCTC
ACCAACTTTTCTTTTTAGATATTGAAATCAAGGGTGAAGAAAAGAAGGGGCTAGACATTGCTAAAGAAATTCGAAAAAAA
GATCCTAATGCAACAATTGTTTTTGTAACAACACACTCAGAATTCATGCCAGTCACTTTTAAATATAGAGTTGCTGCCCT
AGATTTTATTGATAAAGCTTTGAATGATGAGTTTTTTTATGAACGTGTCCGTTTAGCAATTGAATATACTATGGATAAAC
TGGGGGCTACCATTACCCAAGATTCATTTACTTTTGAAACATCAATGGCCCACGTTCAAGTGCCTTTTAACAATATTTTA
TTTTTTGAAACGTCTCCAACAATACATAAGGTTATTTTGCATACTAAAGAAGAAAGAATGGAGTTTTACGCAAGTATTTC
AGAAGTTGAGCGTGCTGACGAACGCTTATATCGATGCCATCGTTCGTTTATCGTTAATCCTGAAAATATCCTTAAAATCA
ACAAAGAAGAAAAAATGGCAATGTTTGATAACAATATTGGATGTCCCATCTCCCGTACGAAATATAGGGGCCTTTTGGAG
AAGGTTAAATCGATGAAAAGCTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-122)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.772	97.571	0.534
comE/comE1	Streptococcus equinus JB1	44.856	98.381	0.441
comE/comE2	Streptococcus gordonii strain NCTC7865	38.057	100	0.381
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.057	100	0.381
comE/comE2	Streptococcus equinus JB1	37.805	99.595	0.377
comE	Streptococcus pneumoniae R6	37.759	97.571	0.368
comE	Streptococcus pneumoniae TIGR4	37.759	97.571	0.368
comE	Streptococcus mitis SK321	37.759	97.571	0.368
comE	Streptococcus mitis NCTC 12261	37.759	97.571	0.368
comE	Streptococcus pneumoniae Rx1	37.759	97.571	0.368
comE	Streptococcus pneumoniae D39	37.759	97.571	0.368
comE	Streptococcus infantis strain Atu-4	36.929	97.571	0.36