Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   ETT71_RS01225 Genome accession   NZ_CP035428
Coordinates   206019..206411 (+) Length   130 a.a.
NCBI ID   WP_136106939.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emmSTG866.1     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 194852..244438 206019..206411 within 0


Gene organization within MGE regions


Location: 194852..244438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT71_RS01120 (ETT71_01120) - 194852..196084 (-) 1233 WP_009880892.1 transglutaminase domain-containing protein -
  ETT71_RS09135 - 196460..197602 (-) 1143 WP_180383156.1 site-specific integrase -
  ETT71_RS01135 (ETT71_01135) - 197729..198262 (-) 534 WP_085577383.1 hypothetical protein -
  ETT71_RS01140 (ETT71_01140) - 198274..198654 (-) 381 WP_002986288.1 ImmA/IrrE family metallo-endopeptidase -
  ETT71_RS01145 (ETT71_01145) - 198664..199011 (-) 348 WP_085577384.1 helix-turn-helix domain-containing protein -
  ETT71_RS01150 (ETT71_01150) - 199302..199466 (+) 165 WP_003057272.1 hypothetical protein -
  ETT71_RS01155 (ETT71_01155) - 199508..199711 (+) 204 WP_003057260.1 hypothetical protein -
  ETT71_RS09275 - 199713..199847 (+) 135 WP_003057293.1 hypothetical protein -
  ETT71_RS01160 (ETT71_01160) - 199844..200212 (+) 369 WP_003057274.1 hypothetical protein -
  ETT71_RS01165 (ETT71_01165) - 200252..200515 (+) 264 WP_136106938.1 hypothetical protein -
  ETT71_RS01170 (ETT71_01170) - 200530..200718 (+) 189 WP_032460866.1 hypothetical protein -
  ETT71_RS01175 (ETT71_01175) dnaB 200705..202045 (+) 1341 WP_032464980.1 replicative DNA helicase -
  ETT71_RS01180 (ETT71_01180) - 202038..202847 (+) 810 WP_136105808.1 conserved phage C-terminal domain-containing protein -
  ETT71_RS01185 (ETT71_01185) - 202847..203659 (+) 813 WP_032464982.1 ATP-binding protein -
  ETT71_RS01190 (ETT71_01190) - 203659..203886 (+) 228 WP_011054424.1 hypothetical protein -
  ETT71_RS01195 (ETT71_01195) - 203900..204106 (+) 207 WP_011054425.1 hypothetical protein -
  ETT71_RS01200 (ETT71_01200) - 204123..204392 (+) 270 WP_023610894.1 hypothetical protein -
  ETT71_RS01205 (ETT71_01205) - 204402..204686 (+) 285 WP_032464983.1 hypothetical protein -
  ETT71_RS01210 (ETT71_01210) - 204688..205320 (+) 633 WP_011054428.1 N-6 DNA methylase -
  ETT71_RS01215 (ETT71_01215) - 205325..205804 (+) 480 WP_032464990.1 DUF1642 domain-containing protein -
  ETT71_RS01220 (ETT71_01220) - 205801..206022 (+) 222 WP_011017369.1 hypothetical protein -
  ETT71_RS01225 (ETT71_01225) ssbA 206019..206411 (+) 393 WP_136106939.1 single-stranded DNA-binding protein Machinery gene
  ETT71_RS01230 (ETT71_01230) - 206425..206703 (+) 279 WP_029713970.1 hypothetical protein -
  ETT71_RS01235 (ETT71_01235) - 206700..207038 (+) 339 WP_085577390.1 helix-turn-helix domain-containing protein -
  ETT71_RS01240 (ETT71_01240) - 207041..207289 (+) 249 WP_085577391.1 hypothetical protein -
  ETT71_RS09140 - 207474..207623 (+) 150 WP_168391464.1 hypothetical protein -
  ETT71_RS01250 (ETT71_01250) - 207592..207792 (+) 201 WP_085577392.1 hypothetical protein -
  ETT71_RS01255 (ETT71_01255) - 207816..208235 (+) 420 WP_085577393.1 DUF1492 domain-containing protein -
  ETT71_RS01260 (ETT71_01260) - 208330..208893 (+) 564 WP_180383159.1 site-specific integrase -
  ETT71_RS01265 (ETT71_01265) - 209065..209358 (+) 294 WP_002986191.1 hypothetical protein -
  ETT71_RS01270 (ETT71_01270) - 209355..209684 (+) 330 WP_085577395.1 HNH endonuclease -
  ETT71_RS01275 (ETT71_01275) - 209806..210153 (+) 348 WP_136106940.1 terminase -
  ETT71_RS01280 (ETT71_01280) - 210134..211792 (+) 1659 WP_002986185.1 terminase TerL endonuclease subunit -
  ETT71_RS01285 (ETT71_01285) - 211991..213226 (+) 1236 WP_003057282.1 phage portal protein -
  ETT71_RS01290 (ETT71_01290) - 213230..213946 (+) 717 WP_136106941.1 head maturation protease, ClpP-related -
  ETT71_RS01295 (ETT71_01295) - 213984..215177 (+) 1194 WP_136106942.1 phage major capsid protein -
  ETT71_RS01300 (ETT71_01300) - 215192..215479 (+) 288 WP_002986176.1 hypothetical protein -
  ETT71_RS01305 (ETT71_01305) - 215499..215792 (+) 294 WP_003057269.1 phage gp6-like head-tail connector protein -
  ETT71_RS01310 (ETT71_01310) - 215794..216171 (+) 378 WP_003057300.1 hypothetical protein -
  ETT71_RS01315 (ETT71_01315) - 216224..216514 (+) 291 WP_227874191.1 hypothetical protein -
  ETT71_RS01320 (ETT71_01320) - 216523..216945 (+) 423 WP_002986168.1 hypothetical protein -
  ETT71_RS01325 (ETT71_01325) - 216964..217551 (+) 588 WP_003057267.1 hypothetical protein -
  ETT71_RS01330 (ETT71_01330) - 217572..217943 (+) 372 WP_071127066.1 hypothetical protein -
  ETT71_RS09145 - 217979..218137 (+) 159 WP_002986162.1 hypothetical protein -
  ETT71_RS01335 (ETT71_01335) - 218211..221447 (+) 3237 WP_085577397.1 phage tail tape measure protein -
  ETT71_RS01340 (ETT71_01340) - 221447..222154 (+) 708 WP_261763409.1 phage tail domain-containing protein -
  ETT71_RS01345 (ETT71_01345) - 222151..224202 (+) 2052 WP_136106943.1 phage tail spike protein -
  ETT71_RS01350 (ETT71_01350) - 224199..225314 (+) 1116 WP_136106944.1 hyaluronoglucosaminidase -
  ETT71_RS01355 (ETT71_01355) - 225324..227228 (+) 1905 WP_136106925.1 gp58-like family protein -
  ETT71_RS01360 (ETT71_01360) - 227240..227668 (+) 429 WP_011018112.1 DUF1617 family protein -
  ETT71_RS01365 (ETT71_01365) - 227671..228276 (+) 606 WP_136106947.1 DUF1366 domain-containing protein -
  ETT71_RS01370 (ETT71_01370) - 228292..228747 (+) 456 WP_002988455.1 phage holin family protein -
  ETT71_RS09280 - 228749..228871 (+) 123 WP_027968869.1 hypothetical protein -
  ETT71_RS01375 (ETT71_01375) - 228859..230067 (+) 1209 WP_136106948.1 glucosaminidase domain-containing protein -
  ETT71_RS01380 (ETT71_01380) - 230140..230343 (-) 204 WP_003055570.1 helix-turn-helix transcriptional regulator -
  ETT71_RS01385 (ETT71_01385) speG 230992..231696 (+) 705 WP_010921857.1 streptococcal pyrogenic exotoxin SpeG -
  ETT71_RS01390 (ETT71_01390) - 232152..233501 (+) 1350 WP_011888573.1 glucose-6-phosphate isomerase -
  ETT71_RS01395 (ETT71_01395) - 233850..235358 (-) 1509 WP_030126942.1 helix-turn-helix domain-containing protein -
  ETT71_RS01400 (ETT71_01400) - 236046..236717 (+) 672 WP_011054156.1 rhomboid family intramembrane serine protease -
  ETT71_RS01405 (ETT71_01405) galU 236816..237715 (-) 900 WP_002986125.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  ETT71_RS01410 (ETT71_01410) - 237748..238764 (-) 1017 WP_032460614.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ETT71_RS01415 (ETT71_01415) - 239062..239511 (+) 450 WP_002986120.1 MarR family winged helix-turn-helix transcriptional regulator -
  ETT71_RS01420 (ETT71_01420) - 239504..241210 (+) 1707 WP_010921864.1 ABC transporter ATP-binding protein -
  ETT71_RS01425 (ETT71_01425) - 241213..242997 (+) 1785 WP_136093695.1 ABC transporter ATP-binding protein -
  ETT71_RS01430 (ETT71_01430) - 243115..243882 (+) 768 WP_002986113.1 epoxyqueuosine reductase QueH -
  ETT71_RS01435 (ETT71_01435) - 243992..244438 (+) 447 WP_023079321.1 dUTP diphosphatase -

Sequence


Protein


Download         Length: 130 a.a.        Molecular weight: 14855.73 Da        Isoelectric Point: 5.8648

>NTDB_id=341040 ETT71_RS01225 WP_136106939.1 206019..206411(+) (ssbA) [Streptococcus pyogenes strain emmSTG866.1]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVMWRQAAENLTNWTKKGHMIAITGRIQTR
NYENQNGQRVYVTEVVAESFQILEKRDNTANTNSLADTMPDYGPEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=341040 ETT71_RS01225 WP_136106939.1 206019..206411(+) (ssbA) [Streptococcus pyogenes strain emmSTG866.1]
ATGATCAATAACGTTGTTTTGATTGGCCGCTTAACAAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTTGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGACAAAAAGAAGCTGATTTTATTAATTGTGTGATGT
GGCGACAAGCTGCTGAAAATTTAACAAATTGGACTAAGAAGGGCCATATGATTGCGATAACAGGACGCATTCAGACCCGT
AACTATGAGAATCAGAATGGTCAACGTGTTTACGTGACAGAAGTGGTTGCCGAAAGTTTTCAAATTTTAGAGAAGCGTGA
TAATACAGCTAATACTAATAGCTTGGCAGATACCATGCCAGACTATGGACCAGAACCAGATTTACCATTTTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

66.355

82.308

0.546

  ssb Latilactobacillus sakei subsp. sakei 23K

63.303

83.846

0.531

  ssbB Streptococcus sobrinus strain NIDR 6715-7

46.212

100

0.469

  ssbA Streptococcus mutans UA159

43.704

100

0.454

  ssbB/cilA Streptococcus pneumoniae TIGR4

43.939

100

0.446

  ssbB/cilA Streptococcus mitis SK321

43.182

100

0.438

  ssbB/cilA Streptococcus mitis NCTC 12261

43.182

100

0.438

  ssbB/cilA Streptococcus pneumoniae D39

43.182

100

0.438

  ssbB/cilA Streptococcus pneumoniae R6

43.182

100

0.438

  ssbB/cilA Streptococcus pneumoniae Rx1

43.182

100

0.438

  ssbB Bacillus subtilis subsp. subtilis str. 168

51.887

81.538

0.423

  ssbB Lactococcus lactis subsp. cremoris KW2

41.085

99.231

0.408


Multiple sequence alignment