Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbB/cilA   Type   Machinery gene
Locus tag   EQH22_RS08770 Genome accession   NZ_CP035258
Coordinates   1744755..1745132 (-) Length   125 a.a.
NCBI ID   WP_000580361.1    Uniprot ID   A0A0T8VDZ4
Organism   Streptococcus pneumoniae strain TVO_1901927     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1742563..1786087 1744755..1745132 within 0


Gene organization within MGE regions


Location: 1742563..1786087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH22_RS08760 (EQH22_09225) groL 1742563..1744185 (-) 1623 WP_000031575.1 chaperonin GroEL -
  EQH22_RS08765 (EQH22_09230) groES 1744201..1744485 (-) 285 WP_000917339.1 co-chaperone GroES -
  EQH22_RS08770 (EQH22_09235) ssbB/cilA 1744755..1745132 (-) 378 WP_000580361.1 single-stranded DNA-binding protein Machinery gene
  EQH22_RS08775 (EQH22_09240) - 1745159..1745401 (-) 243 WP_000698517.1 hypothetical protein -
  EQH22_RS08780 (EQH22_09245) lytA 1745633..1746589 (-) 957 WP_000350534.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EQH22_RS08785 (EQH22_09250) - 1746595..1746924 (-) 330 WP_001186214.1 phage holin -
  EQH22_RS08790 (EQH22_09255) - 1746928..1747227 (-) 300 WP_001810279.1 hypothetical protein -
  EQH22_RS08795 (EQH22_09260) - 1747237..1747587 (-) 351 WP_054393306.1 hypothetical protein -
  EQH22_RS08800 (EQH22_09265) - 1747590..1747793 (-) 204 WP_001091112.1 hypothetical protein -
  EQH22_RS11075 (EQH22_09270) - 1747774..1747890 (-) 117 WP_001063633.1 hypothetical protein -
  EQH22_RS08805 (EQH22_09275) - 1747887..1753133 (-) 5247 WP_409202187.1 tail fiber domain-containing protein -
  EQH22_RS08810 (EQH22_09285) - 1755289..1755639 (-) 351 WP_000068018.1 DUF6711 family protein -
  EQH22_RS08815 (EQH22_09290) - 1755648..1759319 (-) 3672 WP_061754579.1 hypothetical protein -
  EQH22_RS08820 (EQH22_09295) - 1759306..1759656 (-) 351 WP_000478007.1 hypothetical protein -
  EQH22_RS08825 (EQH22_09300) - 1759695..1760075 (-) 381 WP_001185631.1 DUF6096 family protein -
  EQH22_RS08830 (EQH22_09305) - 1760080..1760493 (-) 414 WP_000880665.1 phage tail tube protein -
  EQH22_RS08835 (EQH22_09310) - 1760496..1760864 (-) 369 WP_000608235.1 hypothetical protein -
  EQH22_RS08840 (EQH22_09315) - 1760861..1761376 (-) 516 WP_000015940.1 HK97-gp10 family putative phage morphogenesis protein -
  EQH22_RS08845 (EQH22_09320) - 1761351..1761689 (-) 339 WP_000478943.1 hypothetical protein -
  EQH22_RS08850 (EQH22_09325) - 1761670..1761981 (-) 312 WP_000021218.1 phage head-tail connector protein -
  EQH22_RS08855 (EQH22_09330) - 1761983..1762171 (-) 189 WP_000669348.1 hypothetical protein -
  EQH22_RS08860 (EQH22_09335) - 1762181..1763206 (-) 1026 WP_000863393.1 carbohydrate-binding protein -
  EQH22_RS08865 (EQH22_09340) - 1763229..1763753 (-) 525 WP_001288022.1 DUF4355 domain-containing protein -
  EQH22_RS08870 - 1764020..1764193 (-) 174 WP_000356388.1 hypothetical protein -
  EQH22_RS08875 (EQH22_09345) - 1764235..1764648 (-) 414 WP_000565273.1 HD domain-containing protein -
  EQH22_RS08880 (EQH22_09350) - 1764645..1764854 (-) 210 WP_000651746.1 hypothetical protein -
  EQH22_RS08885 (EQH22_09355) - 1764856..1766493 (-) 1638 WP_164993540.1 minor capsid protein -
  EQH22_RS08890 (EQH22_09360) - 1766402..1767871 (-) 1470 WP_000285392.1 phage portal protein -
  EQH22_RS08895 (EQH22_09365) - 1767883..1769181 (-) 1299 WP_061640473.1 PBSX family phage terminase large subunit -
  EQH22_RS08900 (EQH22_09370) - 1769159..1769599 (-) 441 WP_001841119.1 terminase small subunit -
  EQH22_RS08910 (EQH22_09375) - 1770067..1770471 (-) 405 WP_001030241.1 DUF1492 domain-containing protein -
  EQH22_RS08915 (EQH22_09380) - 1770544..1770915 (-) 372 WP_001247150.1 hypothetical protein -
  EQH22_RS08920 (EQH22_09385) - 1770912..1771349 (-) 438 WP_000188937.1 YopX family protein -
  EQH22_RS08925 (EQH22_09390) - 1771361..1771783 (-) 423 WP_000140868.1 hypothetical protein -
  EQH22_RS08930 (EQH22_09395) - 1771780..1772040 (-) 261 WP_000819329.1 DUF1372 family protein -
  EQH22_RS10925 - 1772037..1772159 (-) 123 WP_001842508.1 hypothetical protein -
  EQH22_RS08935 (EQH22_09400) - 1772198..1772686 (-) 489 WP_001041151.1 DUF1642 domain-containing protein -
  EQH22_RS08940 (EQH22_09405) - 1772688..1773005 (-) 318 WP_000969676.1 hypothetical protein -
  EQH22_RS08945 (EQH22_09410) - 1773030..1773212 (-) 183 WP_000796349.1 hypothetical protein -
  EQH22_RS08950 (EQH22_09415) - 1773228..1773659 (-) 432 WP_000779141.1 RusA family crossover junction endodeoxyribonuclease -
  EQH22_RS08955 (EQH22_09420) - 1773656..1773985 (-) 330 WP_000157070.1 hypothetical protein -
  EQH22_RS08960 (EQH22_09425) - 1773999..1774208 (-) 210 WP_000455270.1 hypothetical protein -
  EQH22_RS08965 - 1774210..1774521 (-) 312 WP_238115198.1 site-specific DNA-methyltransferase -
  EQH22_RS08970 - 1774613..1774894 (-) 282 WP_225791293.1 DNA methyltransferase -
  EQH22_RS08975 (EQH22_09435) ssbA 1774907..1775323 (-) 417 WP_000609559.1 single-stranded DNA-binding protein Machinery gene
  EQH22_RS08980 (EQH22_09440) - 1775418..1775753 (-) 336 WP_000598345.1 sporulation protein Cse60 -
  EQH22_RS08985 (EQH22_09445) - 1775746..1776069 (-) 324 WP_000354630.1 hypothetical protein -
  EQH22_RS08990 (EQH22_09450) - 1776047..1777135 (-) 1089 WP_001157029.1 DUF1351 domain-containing protein -
  EQH22_RS08995 (EQH22_09455) bet 1777145..1777963 (-) 819 WP_000184004.1 phage recombination protein Bet -
  EQH22_RS09000 (EQH22_09460) - 1778233..1778493 (-) 261 WP_000471459.1 hypothetical protein -
  EQH22_RS09005 (EQH22_09465) - 1778506..1778760 (-) 255 WP_000275523.1 hypothetical protein -
  EQH22_RS09010 (EQH22_09470) - 1778761..1778982 (-) 222 WP_000771950.1 hypothetical protein -
  EQH22_RS09015 - 1778982..1779119 (-) 138 WP_000869368.1 hypothetical protein -
  EQH22_RS09020 (EQH22_09475) - 1779137..1779934 (-) 798 WP_001056933.1 ParB N-terminal domain-containing protein -
  EQH22_RS09025 - 1780001..1780144 (-) 144 WP_000389589.1 hypothetical protein -
  EQH22_RS09030 (EQH22_09480) - 1780263..1780454 (+) 192 WP_000834563.1 hypothetical protein -
  EQH22_RS09035 (EQH22_09490) - 1780864..1781184 (-) 321 WP_223687705.1 HTH domain-containing protein -
  EQH22_RS09040 (EQH22_09495) - 1781269..1781496 (-) 228 WP_001125554.1 helix-turn-helix transcriptional regulator -
  EQH22_RS09045 (EQH22_09500) - 1781569..1781775 (+) 207 WP_000133214.1 hypothetical protein -
  EQH22_RS09050 - 1782000..1782170 (-) 171 WP_000660185.1 hypothetical protein -
  EQH22_RS09055 (EQH22_09510) - 1782369..1782818 (+) 450 WP_001058908.1 hypothetical protein -
  EQH22_RS09060 - 1782809..1782976 (-) 168 WP_001005822.1 hypothetical protein -
  EQH22_RS09065 (EQH22_09515) - 1783051..1783326 (-) 276 WP_001094375.1 hypothetical protein -
  EQH22_RS09070 (EQH22_09520) - 1783499..1784290 (+) 792 WP_000090699.1 XRE family transcriptional regulator -
  EQH22_RS09075 (EQH22_09525) - 1784292..1784492 (+) 201 WP_000064302.1 hypothetical protein -
  EQH22_RS09080 (EQH22_09530) - 1784660..1786087 (+) 1428 WP_000859012.1 recombinase family protein -

Sequence

Protein


Download         Length: 125 a.a.        Molecular weight: 14176.95 Da        Isoelectric Point: 5.2813

>NTDB_id=338169 EQH22_RS08770 WP_000580361.1 1744755..1745132(-) (ssbB/cilA) [Streptococcus pneumoniae strain TVO_1901927]
MIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNG
QMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 378 bp        

>NTDB_id=338169 EQH22_RS08770 WP_000580361.1 1744755..1745132(-) (ssbB/cilA) [Streptococcus pneumoniae strain TVO_1901927]
ATGATTGGGCGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCGGTAGCGCGAGCAACTATCGCTGT
CAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGCTGATTTTGTCAATATGGTCCTATGGGGCAGACTAGCAGAAA
CTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGTCGCTTTGAGAAAAATGGC
CAAATGAACTACGTGACCGAAGTACTTGTAACAGGATTCCAACTCTTGGAAAGTCGTGCTCAACGTGCCATGCGTGAAAA
TAATGCAGGCCAAGATTTGGCAGATTTAGTCTTGGAAGAGGAAGAATTGCCATTTTAA

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(1-95)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8VDZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae D39

100

100

1
  ssbB/cilA Streptococcus pneumoniae Rx1

100

100

1
  ssbB/cilA Streptococcus pneumoniae R6

100

100

1
  ssbB/cilA Streptococcus pneumoniae TIGR4

99.2

100

0.992
  ssbB/cilA Streptococcus mitis SK321

98.4

100

0.984
  ssbB/cilA Streptococcus mitis NCTC 12261

98.4

100

0.984
  ssbA Streptococcus mutans UA159

73.6

100

0.736
  ssbB Streptococcus sobrinus strain NIDR 6715-7

68.8

100

0.688
  ssbB Lactococcus lactis subsp. cremoris KW2

60.185

86.4

0.52
  ssbA Bacillus subtilis subsp. subtilis str. 168

51

80

0.408
  ssb Latilactobacillus sakei subsp. sakei 23K

46.729

85.6

0.4

Multiple sequence alignment