Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FYA12_RS09825 Genome accession   NZ_CP043197
Coordinates   2012752..2013342 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O16:H48 strain PG20180061     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007752..2018342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYA12_RS09795 (FYA12_09795) yidF 2007867..2008364 (+) 498 WP_000148061.1 radical SAM protein -
  FYA12_RS09800 (FYA12_09800) emrD 2008372..2009556 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FYA12_RS22970 ysdE 2009638..2009712 (+) 75 WP_211180519.1 protein YsdE -
  FYA12_RS09805 (FYA12_09805) tisB 2009836..2009925 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  FYA12_RS09810 (FYA12_09810) ivbL 2010490..2010588 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FYA12_RS09815 (FYA12_09815) ilvB 2010694..2012382 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FYA12_RS09820 (FYA12_09820) ilvN 2012386..2012676 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FYA12_RS09825 (FYA12_09825) letA 2012752..2013342 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FYA12_RS09830 (FYA12_09830) uhpB 2013342..2014844 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FYA12_RS09835 (FYA12_09835) uhpC 2014854..2016173 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FYA12_RS09840 (FYA12_09840) uhpT 2016311..2017702 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=335070 FYA12_RS09825 WP_000633668.1 2012752..2013342(+) (letA) [Escherichia coli O16:H48 strain PG20180061]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=335070 FYA12_RS09825 WP_000633668.1 2012752..2013342(+) (letA) [Escherichia coli O16:H48 strain PG20180061]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment