Detailed information NTG0329525

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: EH197_RS11605
• Genome accession: NZ_CP034169
• Coordinates: 2254481..2254747 (+)
• Length: 88 a.a.
• NCBI ID: WP_016181444.1
• Uniprot ID: A0A2N8PXL3
• Organism: Enterococcus avium strain 352
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2249481..2259747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EH197_RS11580 (EH197_11580)	dat	2249967..2250836 (+)	870	WP_016181439.1	D-amino-acid transaminase	-
EH197_RS11585 (EH197_11585)	-	2250926..2251708 (+)	783	WP_016181440.1	phosphotransferase family protein	-
EH197_RS11590 (EH197_11590)	trmB	2251818..2252468 (+)	651	WP_016181441.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
EH197_RS11595 (EH197_11595)	comGA	2252561..2253511 (+)	951	WP_127979482.1	competence type IV pilus ATPase ComGA	-
EH197_RS11600 (EH197_11600)	comGB	2253471..2254484 (+)	1014	WP_137439783.1	competence type IV pilus assembly protein ComGB	-
EH197_RS11605 (EH197_11605)	comYC	2254481..2254747 (+)	267	WP_016181444.1	competence type IV pilus major pilin ComGC	Machinery gene
EH197_RS11610 (EH197_11610)	comGD	2254731..2255186 (+)	456	WP_137439784.1	competence type IV pilus minor pilin ComGD	-
EH197_RS11615 (EH197_11615)	comGE	2255164..2255445 (+)	282	WP_227655542.1	competence type IV pilus minor pilin ComGE	-
EH197_RS11620 (EH197_11620)	comGF	2255432..2255857 (+)	426	WP_048718834.1	competence type IV pilus minor pilin ComGF	-
EH197_RS11625 (EH197_11625)	comGG	2255820..2256170 (+)	351	WP_270307845.1	competence type IV pilus minor pilin ComGG	-
EH197_RS11630 (EH197_11630)	-	2256336..2257343 (+)	1008	WP_137439786.1	class I SAM-dependent methyltransferase	-
EH197_RS11635 (EH197_11635)	-	2257391..2258587 (+)	1197	WP_016181450.1	acetate kinase	-
EH197_RS11640 (EH197_11640)	-	2258760..2259110 (+)	351	WP_016181451.1	BMC domain-containing protein	-
EH197_RS11645 (EH197_11645)	eutP	2259113..2259553 (+)	441	WP_137440467.1	EutP/PduV family microcompartment system protein	-

Sequence

Protein

• Length: 88 a.a.
• Molecular weight: 10058.89 Da
• Isoelectric Point: 8.3736

>NTDB_id=329525 EH197_RS11605 WP_016181444.1 2254481..2254747(+) (comYC) [Enterococcus avium strain 352]
MKKKLSGFTLLEMLVVLFIISLLLLLFVPKLMSQKESATNKSDAAIVKVVETQIEVFELDYGRKPEEGELVSKGYVSEDQ
YNKYVQKK

Nucleotide

• Length: 267 bp

>NTDB_id=329525 EH197_RS11605 WP_016181444.1 2254481..2254747(+) (comYC) [Enterococcus avium strain 352]
GTGAAGAAGAAGCTTTCAGGTTTTACTTTGTTGGAAATGTTAGTTGTTTTATTTATTATTAGTCTGCTATTGCTGTTATT
TGTGCCAAAACTAATGAGTCAAAAAGAAAGCGCAACCAACAAGAGCGATGCTGCTATTGTCAAAGTTGTTGAGACACAAA
TTGAAGTCTTTGAACTGGATTATGGACGTAAGCCAGAGGAAGGTGAATTAGTCAGTAAAGGTTATGTTAGTGAAGACCAG
TATAATAAATATGTACAAAAGAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (3-26)

3D structure

• AlphaFold DB: A0A2N8PXL3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	54.118	96.591	0.523
comGC/cglC	Streptococcus mitis SK321	50.562	100	0.511
comGC/cglC	Streptococcus mitis NCTC 12261	50.602	94.318	0.477
comYC	Streptococcus gordonii str. Challis substr. CH1	48.81	95.455	0.466
comGC/cglC	Streptococcus pneumoniae D39	48.193	94.318	0.455
comGC/cglC	Streptococcus pneumoniae R6	48.193	94.318	0.455
comGC/cglC	Streptococcus pneumoniae TIGR4	48.193	94.318	0.455
comGC/cglC	Streptococcus pneumoniae Rx1	48.193	94.318	0.455
comGC	Lactococcus lactis subsp. cremoris KW2	47.619	95.455	0.455
comYC	Streptococcus mutans UA140	47.5	90.909	0.432
comYC	Streptococcus mutans UA159	47.5	90.909	0.432
comGC	Latilactobacillus sakei subsp. sakei 23K	43.75	90.909	0.398
comGC	Staphylococcus aureus MW2	43.038	89.773	0.386
comGC	Staphylococcus aureus N315	43.038	89.773	0.386
comGC	Bacillus subtilis subsp. subtilis str. 168	43.243	84.091	0.364