Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SUB_RS00740 Genome accession   NC_012004
Coordinates   124780..125103 (+) Length   107 a.a.
NCBI ID   WP_012657675.1    Uniprot ID   -
Organism   Streptococcus uberis 0140J     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 119780..130103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS00725 (SUB0117) - 122433..122798 (+) 366 WP_041817508.1 DUF1033 family protein -
  SUB_RS00730 (SUB0118) comGA/cglA 122871..123812 (+) 942 WP_012657673.1 competence type IV pilus ATPase ComGA Machinery gene
  SUB_RS00735 (SUB0119) comYB 123724..124779 (+) 1056 WP_172631729.1 competence type IV pilus assembly protein ComGB Machinery gene
  SUB_RS00740 (SUB0120) comGC/cglC 124780..125103 (+) 324 WP_012657675.1 competence type IV pilus major pilin ComGC Machinery gene
  SUB_RS00745 (SUB0121) comGD 125057..125494 (+) 438 WP_012657676.1 competence type IV pilus minor pilin ComGD -
  SUB_RS00750 (SUB0122) comGE 125466..125765 (+) 300 WP_012657677.1 competence type IV pilus minor pilin ComGE -
  SUB_RS00755 (SUB0123) comGF 125725..126180 (+) 456 WP_012657678.1 competence type IV pilus minor pilin ComGF -
  SUB_RS00760 (SUB0124) comGG 126158..126517 (+) 360 WP_012657679.1 competence type IV pilus minor pilin ComGG -
  SUB_RS00765 (SUB0125) comYH 126562..127518 (+) 957 WP_012657680.1 class I SAM-dependent methyltransferase Machinery gene
  SUB_RS00770 (SUB0126) - 127574..128764 (+) 1191 WP_012657681.1 acetate kinase -
  SUB_RS00775 (SUB0127) - 128882..129085 (+) 204 WP_012657682.1 helix-turn-helix transcriptional regulator -
  SUB_RS00780 (SUB0128) - 129087..129539 (+) 453 WP_012657683.1 hypothetical protein -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12304.58 Da        Isoelectric Point: 9.9864

>NTDB_id=32906 SUB_RS00740 WP_012657675.1 124780..125103(+) (comGC/cglC) [Streptococcus uberis 0140J]
MKKWMKTLENKKAKAFTLLEMLMVLLIISVLMLLFIPNLSKQKEKVTDKGNAAVVKIVENQAELYELNEGKKPNLSELVQ
NGNITKKQVEAYNDYYQKHPGENKLLP

Nucleotide


Download         Length: 324 bp        

>NTDB_id=32906 SUB_RS00740 WP_012657675.1 124780..125103(+) (comGC/cglC) [Streptococcus uberis 0140J]
ATGAAAAAATGGATGAAAACTTTAGAAAACAAGAAGGCAAAAGCTTTCACACTTTTAGAAATGCTAATGGTCCTTCTGAT
CATCAGCGTGCTCATGCTTTTATTTATTCCCAATTTAAGCAAGCAAAAAGAAAAGGTAACCGATAAAGGAAATGCTGCAG
TTGTGAAAATTGTAGAAAATCAAGCAGAGCTCTATGAATTGAATGAAGGGAAAAAACCTAATTTAAGTGAGTTAGTACAA
AATGGTAATATCACTAAAAAACAAGTAGAGGCATATAATGACTATTATCAAAAACATCCTGGTGAAAATAAGCTGTTGCC
ATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

61.538

97.196

0.598
  comYC Streptococcus gordonii str. Challis substr. CH1

62.376

94.393

0.589
  comGC/cglC Streptococcus pneumoniae TIGR4

58.654

97.196

0.57
  comGC/cglC Streptococcus pneumoniae Rx1

58.654

97.196

0.57
  comGC/cglC Streptococcus pneumoniae D39

58.654

97.196

0.57
  comGC/cglC Streptococcus pneumoniae R6

58.654

97.196

0.57
  comGC/cglC Streptococcus mitis NCTC 12261

60.606

92.523

0.561
  comGC Lactococcus lactis subsp. cremoris KW2

59

93.458

0.551
  comYC Streptococcus mutans UA140

58

93.458

0.542
  comYC Streptococcus mutans UA159

58

93.458

0.542
  comYC Streptococcus suis isolate S10

54.545

82.243

0.449

Multiple sequence alignment