Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   SP670_RS10785 Genome accession   NC_014498
Coordinates   1989514..1989780 (-) Length   88 a.a.
NCBI ID   WP_000962026.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 670-6B     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1984514..1994780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP670_RS10740 (SP670_2122) rnpA 1984539..1984910 (-) 372 WP_000739241.1 ribonuclease P protein component -
  SP670_RS10745 (SP670_2123) - 1985058..1986248 (-) 1191 WP_000167766.1 acetate kinase -
  SP670_RS10750 (SP670_2124) comGH 1986299..1987252 (-) 954 WP_000345085.1 class I SAM-dependent methyltransferase Machinery gene
  SP670_RS13660 - 1987313..1987900 (-) 588 Protein_2022 class I SAM-dependent methyltransferase -
  SP670_RS10765 (SP670_2127) comGG/cglG 1988037..1988450 (-) 414 WP_000265619.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP670_RS10770 (SP670_2128) comGF/cglF 1988428..1988889 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP670_RS10775 (SP670_2129) comGE/cglE 1988852..1989154 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP670_RS10780 (SP670_2130) comGD/cglD 1989117..1989521 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP670_RS10785 (SP670_2131) comGC/cglC 1989514..1989780 (-) 267 WP_000962026.1 competence type IV pilus major pilin ComGC Machinery gene
  SP670_RS10790 (SP670_2132) - 1989782..1990039 (-) 258 WP_000698513.1 hypothetical protein -
  SP670_RS10795 (SP670_2133) - 1990271..1991227 (-) 957 WP_000350474.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SP670_RS10800 (SP670_2134) - 1991227..1991562 (-) 336 WP_001186218.1 phage holin -
  SP670_RS10805 (SP670_2135) - 1991566..1991865 (-) 300 WP_001811580.1 hypothetical protein -
  SP670_RS10810 (SP670_2136) - 1991874..1992224 (-) 351 WP_000852245.1 hypothetical protein -
  SP670_RS10815 (SP670_2137) - 1992227..1992430 (-) 204 WP_001091115.1 hypothetical protein -
  SP670_RS14675 (SP670_2138) - 1992411..1992527 (-) 117 WP_001063633.1 hypothetical protein -

Sequence


Protein


Download         Length: 88 a.a.        Molecular weight: 9818.31 Da        Isoelectric Point: 7.0116

>NTDB_id=32875 SP670_RS10785 WP_000962026.1 1989514..1989780(-) (comGC/cglC) [Streptococcus pneumoniae 670-6B]
MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQADGRITEEQAKAYKEYHDKNG
VANRKVND

Nucleotide


Download         Length: 267 bp        

>NTDB_id=32875 SP670_RS10785 WP_000962026.1 1989514..1989780(-) (comGC/cglC) [Streptococcus pneumoniae 670-6B]
ATGTTGGTGGTCTTGCTGATTATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAA
TGACAAAGGAAAAGCAGCTGTTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTA
GCCTAAGCAAGTTACAAGCAGATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGA
GTAGCAAATCGTAAAGTCAATGATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

97.727

100

0.977

  comGC/cglC Streptococcus pneumoniae D39

97.727

100

0.977

  comGC/cglC Streptococcus pneumoniae R6

97.727

100

0.977

  comGC/cglC Streptococcus pneumoniae TIGR4

96.591

100

0.966

  comGC/cglC Streptococcus mitis SK321

93.243

84.091

0.784

  comGC/cglC Streptococcus mitis NCTC 12261

91.176

77.273

0.705

  comGC Streptococcus gordonii str. Challis substr. CH1

72.5

90.909

0.659

  comGC Streptococcus suis isolate S10

68.056

81.818

0.557

  comGC Streptococcus mutans UA140

61.429

79.545

0.489

  comGC Streptococcus mutans UA159

61.429

79.545

0.489

  comGC Lactococcus lactis subsp. cremoris KW2

50.667

85.227

0.432

  comGC Staphylococcus aureus MW2

47.826

78.409

0.375

  comGC Staphylococcus aureus N315

47.826

78.409

0.375


Multiple sequence alignment