Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EGX70_RS06960 Genome accession   NZ_CP033808
Coordinates   1356691..1357020 (-) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus sp. FDAARGOS_522     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1351691..1362020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS06915 (EGX70_06915) - 1351904..1352359 (-) 456 WP_000905673.1 hypothetical protein -
  EGX70_RS06920 (EGX70_06920) - 1352400..1352537 (-) 138 WP_001865900.1 hypothetical protein -
  EGX70_RS06925 (EGX70_06925) - 1352596..1352802 (-) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  EGX70_RS06930 (EGX70_06930) - 1352954..1354147 (-) 1194 WP_000047534.1 acetate kinase -
  EGX70_RS06935 (EGX70_06935) comYH 1354179..1355153 (-) 975 WP_123948044.1 class I SAM-dependent methyltransferase Machinery gene
  EGX70_RS06940 (EGX70_06940) comGG 1355268..1355639 (-) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  EGX70_RS06945 (EGX70_06945) comGF 1355617..1356078 (-) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  EGX70_RS06950 (EGX70_06950) comGE 1356032..1356331 (-) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  EGX70_RS06955 (EGX70_06955) comYD 1356303..1356716 (-) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX70_RS06960 (EGX70_06960) comGC/cglC 1356691..1357020 (-) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX70_RS06965 (EGX70_06965) comYB 1357017..1358060 (-) 1044 WP_301182249.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX70_RS06970 (EGX70_06970) comYA 1357954..1358925 (-) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX70_RS06980 (EGX70_06980) - 1359098..1359463 (-) 366 WP_000285373.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=325836 EGX70_RS06960 WP_000793380.1 1356691..1357020(-) (comGC/cglC) [Streptococcus sp. FDAARGOS_522]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=325836 EGX70_RS06960 WP_000793380.1 1356691..1357020(-) (comGC/cglC) [Streptococcus sp. FDAARGOS_522]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment