Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EGX70_RS06965 Genome accession   NZ_CP033808
Coordinates   1357017..1358060 (-) Length   347 a.a.
NCBI ID   WP_301182249.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_522     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1352017..1363060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS06920 (EGX70_06920) - 1352400..1352537 (-) 138 WP_001865900.1 hypothetical protein -
  EGX70_RS06925 (EGX70_06925) - 1352596..1352802 (-) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  EGX70_RS06930 (EGX70_06930) - 1352954..1354147 (-) 1194 WP_000047534.1 acetate kinase -
  EGX70_RS06935 (EGX70_06935) comYH 1354179..1355153 (-) 975 WP_123948044.1 class I SAM-dependent methyltransferase Machinery gene
  EGX70_RS06940 (EGX70_06940) comGG 1355268..1355639 (-) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  EGX70_RS06945 (EGX70_06945) comGF 1355617..1356078 (-) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  EGX70_RS06950 (EGX70_06950) comGE 1356032..1356331 (-) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  EGX70_RS06955 (EGX70_06955) comYD 1356303..1356716 (-) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX70_RS06960 (EGX70_06960) comGC/cglC 1356691..1357020 (-) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX70_RS06965 (EGX70_06965) comYB 1357017..1358060 (-) 1044 WP_301182249.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX70_RS06970 (EGX70_06970) comYA 1357954..1358925 (-) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX70_RS06980 (EGX70_06980) - 1359098..1359463 (-) 366 WP_000285373.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39902.63 Da        Isoelectric Point: 9.9002

>NTDB_id=325837 EGX70_RS06965 WP_301182249.1 1357017..1358060(-) (comYB) [Streptococcus sp. FDAARGOS_522]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDSMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRNYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGIELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
LIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=325837 EGX70_RS06965 WP_301182249.1 1357017..1358060(-) (comYB) [Streptococcus sp. FDAARGOS_522]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGTATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGAATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTATTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCCGTTATT
TTAATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(34-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

61.877

98.271

0.608
  comYB Streptococcus mutans UA159

61.584

98.271

0.605
  comYB Streptococcus gordonii str. Challis substr. CH1

56.012

98.271

0.55
  comGB/cglB Streptococcus mitis NCTC 12261

54.925

96.542

0.53
  comGB/cglB Streptococcus mitis SK321

54.328

96.542

0.524
  comGB/cglB Streptococcus pneumoniae Rx1

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae D39

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae R6

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae TIGR4

53.433

96.542

0.516
  comGB Lactococcus lactis subsp. cremoris KW2

49.852

97.118

0.484

Multiple sequence alignment