Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EGX70_RS06935 Genome accession   NZ_CP033808
Coordinates   1354179..1355153 (-) Length   324 a.a.
NCBI ID   WP_123948044.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_522     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1349179..1360153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS06900 (EGX70_06900) pepA 1349242..1350309 (+) 1068 WP_001281323.1 glutamyl aminopeptidase -
  EGX70_RS06905 (EGX70_06905) proC 1350379..1351149 (+) 771 WP_001865901.1 pyrroline-5-carboxylate reductase -
  EGX70_RS06910 (EGX70_06910) - 1351170..1351835 (-) 666 WP_000008113.1 CPBP family intramembrane glutamic endopeptidase -
  EGX70_RS06915 (EGX70_06915) - 1351904..1352359 (-) 456 WP_000905673.1 hypothetical protein -
  EGX70_RS06920 (EGX70_06920) - 1352400..1352537 (-) 138 WP_001865900.1 hypothetical protein -
  EGX70_RS06925 (EGX70_06925) - 1352596..1352802 (-) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  EGX70_RS06930 (EGX70_06930) - 1352954..1354147 (-) 1194 WP_000047534.1 acetate kinase -
  EGX70_RS06935 (EGX70_06935) comYH 1354179..1355153 (-) 975 WP_123948044.1 class I SAM-dependent methyltransferase Machinery gene
  EGX70_RS06940 (EGX70_06940) comGG 1355268..1355639 (-) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  EGX70_RS06945 (EGX70_06945) comGF 1355617..1356078 (-) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  EGX70_RS06950 (EGX70_06950) comGE 1356032..1356331 (-) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  EGX70_RS06955 (EGX70_06955) comYD 1356303..1356716 (-) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX70_RS06960 (EGX70_06960) comGC/cglC 1356691..1357020 (-) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX70_RS06965 (EGX70_06965) comYB 1357017..1358060 (-) 1044 WP_301182249.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX70_RS06970 (EGX70_06970) comYA 1357954..1358925 (-) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX70_RS06980 (EGX70_06980) - 1359098..1359463 (-) 366 WP_000285373.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37012.00 Da        Isoelectric Point: 4.5224

>NTDB_id=325834 EGX70_RS06935 WP_123948044.1 1354179..1355153(-) (comYH) [Streptococcus sp. FDAARGOS_522]
MNLEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide


Download         Length: 975 bp        

>NTDB_id=325834 EGX70_RS06935 WP_123948044.1 1354179..1355153(-) (comYH) [Streptococcus sp. FDAARGOS_522]
ATGAATTTGGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(70-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

66.984

97.222

0.651
  comYH Streptococcus mutans UA140

66.984

97.222

0.651

Multiple sequence alignment