Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EGX75_RS10410 Genome accession   NZ_CP033787
Coordinates   2062877..2063152 (+) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain FDAARGOS_528     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2057877..2068152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX75_RS10385 (EGX75_10385) rlmN 2057975..2059048 (+) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  EGX75_RS10395 (EGX75_10395) - 2059338..2060666 (+) 1329 WP_002360022.1 amino acid permease -
  EGX75_RS10400 (EGX75_10400) comGA 2060907..2061875 (+) 969 WP_002360023.1 competence type IV pilus ATPase ComGA -
  EGX75_RS10405 (EGX75_10405) comGB 2061832..2062877 (+) 1046 Protein_1925 competence type IV pilus assembly protein ComGB -
  EGX75_RS10410 (EGX75_10410) comGC/cglC 2062877..2063152 (+) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX75_RS10415 (EGX75_10415) comGD 2063149..2063583 (+) 435 Protein_1927 competence type IV pilus minor pilin ComGD -
  EGX75_RS10420 (EGX75_10420) - 2063620..2064768 (-) 1149 WP_002387264.1 site-specific integrase -
  EGX75_RS10425 (EGX75_10425) - 2064874..2065503 (-) 630 WP_002387265.1 SHOCT domain-containing protein -
  EGX75_RS10430 (EGX75_10430) - 2065599..2066249 (-) 651 WP_123839694.1 ImmA/IrrE family metallo-endopeptidase -
  EGX75_RS10435 (EGX75_10435) - 2066254..2066595 (-) 342 WP_002387267.1 helix-turn-helix transcriptional regulator -
  EGX75_RS10440 (EGX75_10440) - 2066891..2067082 (+) 192 WP_002383936.1 hypothetical protein -
  EGX75_RS10445 (EGX75_10445) - 2067094..2067405 (+) 312 WP_002403885.1 hypothetical protein -
  EGX75_RS10450 (EGX75_10450) - 2067428..2068150 (+) 723 WP_002387270.1 phage regulatory protein -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=325725 EGX75_RS10410 WP_002356991.1 2062877..2063152(+) (comGC/cglC) [Enterococcus faecalis strain FDAARGOS_528]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=325725 EGX75_RS10410 WP_002356991.1 2062877..2063152(+) (comGC/cglC) [Enterococcus faecalis strain FDAARGOS_528]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCTTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

46.835

86.813

0.407
  comGC Staphylococcus aureus N315

46.835

86.813

0.407
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396

Multiple sequence alignment