Detailed information NTG0325168

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: EGX58_RS10280
• Genome accession: NZ_CP033732
• Coordinates: 2026931..2027242 (+)
• Length: 103 a.a.
• NCBI ID: WP_002449700.1
• Uniprot ID: -
• Organism: Staphylococcus hominis strain FDAARGOS_575
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2021931..2032242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX58_RS10250 (EGX58_10260)	-	2022714..2022917 (+)	204	WP_037555982.1	YqgQ family protein	-
EGX58_RS10255 (EGX58_10265)	-	2022914..2023900 (+)	987	WP_002449785.1	ROK family glucokinase	-
EGX58_RS10260 (EGX58_10270)	-	2023900..2024223 (+)	324	WP_103288190.1	MTH1187 family thiamine-binding protein	-
EGX58_RS10265 (EGX58_10275)	-	2024225..2024851 (+)	627	WP_002449717.1	MBL fold metallo-hydrolase	-
EGX58_RS10270 (EGX58_10280)	comGA	2024902..2025876 (+)	975	WP_002449861.1	competence type IV pilus ATPase ComGA	Machinery gene
EGX58_RS10275 (EGX58_10285)	comGB	2025848..2026912 (+)	1065	WP_002455292.1	competence type IV pilus assembly protein ComGB	-
EGX58_RS10280 (EGX58_10290)	comGC	2026931..2027242 (+)	312	WP_002449700.1	competence type IV pilus major pilin ComGC	Machinery gene
EGX58_RS10285 (EGX58_10295)	comGD	2027232..2027666 (+)	435	WP_002449773.1	competence type IV pilus minor pilin ComGD	-
EGX58_RS10290 (EGX58_10300)	-	2027858..2028355 (+)	498	WP_002449908.1	competence protein ComG	-
EGX58_RS10300 (EGX58_10310)	-	2028520..2029029 (+)	510	WP_002449809.1	shikimate kinase	-
EGX58_RS10305 (EGX58_10315)	gcvT	2029221..2030312 (+)	1092	WP_002455297.1	glycine cleavage system aminomethyltransferase GcvT	-
EGX58_RS10310 (EGX58_10320)	gcvPA	2030329..2031681 (+)	1353	WP_002455298.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11420.60 Da
• Isoelectric Point: 9.7125

>NTDB_id=325168 EGX58_RS10280 WP_002449700.1 2026931..2027242(+) (comGC) [Staphylococcus hominis strain FDAARGOS_575]
MKKFKHKLKAFTLIEMLLVLLIISVLLILIIPNIAKQMAHIQSTGCEAQVKMVNSQIEAYTLKHNRVPNSIENLITEGFI
KQGQSSCKSGETISIKNGEAVAE

Nucleotide

• Length: 312 bp

>NTDB_id=325168 EGX58_RS10280 WP_002449700.1 2026931..2027242(+) (comGC) [Staphylococcus hominis strain FDAARGOS_575]
ATGAAAAAATTCAAACATAAATTAAAAGCTTTTACTTTAATCGAGATGTTACTTGTACTATTAATAATTAGTGTTTTACT
CATTCTTATTATTCCAAACATAGCTAAACAAATGGCACATATTCAATCAACAGGATGTGAAGCACAAGTGAAAATGGTCA
ATAGTCAAATTGAAGCTTATACTTTAAAACATAATAGAGTTCCTAATTCTATTGAGAACTTAATAACTGAAGGGTTTATA
AAACAAGGGCAATCATCTTGTAAGTCTGGAGAAACTATCAGTATTAAAAATGGAGAAGCAGTTGCAGAGTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (7-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus N315	80.392	99.029	0.796
comGC	Staphylococcus aureus MW2	80.392	99.029	0.796
comGC/cglC	Streptococcus mitis SK321	46.875	93.204	0.437
comGC/cglC	Streptococcus pneumoniae R6	45.833	93.204	0.427
comGC/cglC	Streptococcus pneumoniae TIGR4	45.833	93.204	0.427
comGC/cglC	Streptococcus pneumoniae Rx1	45.833	93.204	0.427
comGC/cglC	Streptococcus pneumoniae D39	45.833	93.204	0.427
comYC	Streptococcus mutans UA159	47.191	86.408	0.408
comYC	Streptococcus mutans UA140	47.191	86.408	0.408
comGC	Bacillus subtilis subsp. subtilis str. 168	43.158	92.233	0.398
comYC	Streptococcus gordonii str. Challis substr. CH1	46.591	85.437	0.398
comGC/cglC	Streptococcus mitis NCTC 12261	48.193	80.583	0.388
comYC	Streptococcus suis isolate S10	45.349	83.495	0.379
comGC	Lactococcus lactis subsp. cremoris KW2	48.718	75.728	0.369