Detailed information NTG0317230

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: D7D53_RS09110
• Genome accession: NZ_CP032621
• Coordinates: 1800255..1801007 (+)
• Length: 250 a.a.
• NCBI ID: WP_033682534.1
• Uniprot ID: -
• Organism: Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1795255..1806007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7D53_RS09080 (D7D53_09080)	spo0J	1795826..1796584 (-)	759	WP_120770757.1	ParB/RepB/Spo0J family partition protein	Regulator
D7D53_RS09085 (D7D53_09085)	htrA	1796642..1797823 (-)	1182	WP_120770758.1	S1C family serine protease	Regulator
D7D53_RS09090 (D7D53_09090)	rlmH	1798007..1798486 (+)	480	WP_120770759.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
D7D53_RS09100 (D7D53_09100)	comC/comC2	1798770..1798892 (+)	123	WP_120770760.1	competence-stimulating peptide ComC	Regulator
D7D53_RS09105 (D7D53_09105)	comD/comD2	1798909..1800258 (+)	1350	WP_120770761.1	competence system sensor histidine kinase ComD	Regulator
D7D53_RS09110 (D7D53_09110)	comE	1800255..1801007 (+)	753	WP_033682534.1	competence system response regulator transcription factor ComE	Regulator
D7D53_RS09125 (D7D53_09125)	-	1801250..1801792 (-)	543	WP_049552685.1	TetR/AcrR family transcriptional regulator	-
D7D53_RS09130 (D7D53_09130)	-	1801920..1804562 (+)	2643	WP_120770762.1	YhgE/Pip domain-containing protein	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29933.29 Da
• Isoelectric Point: 6.9819

>NTDB_id=317230 D7D53_RS09110 WP_033682534.1 1800255..1801007(+) (comE) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFKEYIENDEVNQLYFLDIDIHGIEKKGFEVAQFIRHHNP
YAIIVFITSRSEFATLTYKYQVSALDFVDKDINDELFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRKNLEVVFYEDHRCPISRLKIRKL
KDILEKKSQK

Nucleotide

• Length: 753 bp

>NTDB_id=317230 D7D53_RS09110 WP_033682534.1 1800255..1801007(+) (comE) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAAAGTTTTAATTTTAGAAGATGTTATTGAACATCAAGTGAGACTAGAGAGAATATTGGATGAAATTTCGAAAGAATC
GAATATTCCAATATCATACAAGACAACGGGAAAAGTTCGTGAGTTTAAGGAATATATCGAAAATGATGAAGTAAACCAGC
TTTATTTTCTAGATATTGATATTCATGGAATTGAGAAAAAAGGGTTTGAAGTTGCTCAGTTTATTCGTCATCACAATCCT
TATGCTATTATCGTCTTTATCACCAGTCGATCAGAGTTTGCGACTCTAACCTATAAATACCAGGTATCAGCCTTAGACTT
TGTTGATAAGGATATTAATGATGAGTTATTTAAGAAGAGAATTGAGCAAAATATCTTCTACACGAAGAGTATGTTACTTG
AAAATGAAGATGTTGTAGATTATTTTGACTACAATTACAAGGGAAATGATTTAAAAATTCCTTATCATGACATTCTGTAT
ATTGAAACGACAGGTGTCTCTCATAAATTGCGTATTATTGGTAAGAATTTTGCAAAAGAATTTTATGGTACAATGACGGA
TATTCAGGAAAAGGACAAACATACTCAGCGATTTTATTCTCCTCATAAGTCATTTTTGGTAAATATAGGCAATATTAGAG
AAATTGACCGAAAGAATCTAGAAGTTGTTTTCTATGAAGATCATCGCTGTCCTATTTCAAGGTTAAAAATTAGAAAGTTA
AAAGATATTTTAGAGAAAAAATCTCAAAAGTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-121)

• LytTr DNA-binding domain (LytTR) (151-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	99.6	100	0.996
comE	Streptococcus mitis SK321	98.8	100	0.988
comE	Streptococcus pneumoniae Rx1	98	100	0.98
comE	Streptococcus pneumoniae D39	98	100	0.98
comE	Streptococcus pneumoniae R6	98	100	0.98
comE	Streptococcus pneumoniae TIGR4	98	100	0.98
comE	Streptococcus infantis strain Atu-4	93.2	100	0.932
comE/comE2	Streptococcus gordonii strain NCTC7865	64.4	100	0.644
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	64.4	100	0.644
comE/blpR	Streptococcus mutans UA159	41.7	98.8	0.412