Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   D7D53_RS09105 Genome accession   NZ_CP032621
Coordinates   1798909..1800258 (+) Length   449 a.a.
NCBI ID   WP_120770761.1    Uniprot ID   A0A387B2F3
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1793909..1805258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS09075 (D7D53_09075) dnaA 1794252..1795613 (-) 1362 WP_120770756.1 chromosomal replication initiator protein DnaA -
  D7D53_RS09080 (D7D53_09080) spo0J 1795826..1796584 (-) 759 WP_120770757.1 ParB/RepB/Spo0J family partition protein Regulator
  D7D53_RS09085 (D7D53_09085) htrA 1796642..1797823 (-) 1182 WP_120770758.1 S1C family serine protease Regulator
  D7D53_RS09090 (D7D53_09090) rlmH 1798007..1798486 (+) 480 WP_120770759.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  D7D53_RS09100 (D7D53_09100) comC/comC2 1798770..1798892 (+) 123 WP_120770760.1 competence-stimulating peptide ComC Regulator
  D7D53_RS09105 (D7D53_09105) comD/comD2 1798909..1800258 (+) 1350 WP_120770761.1 competence system sensor histidine kinase ComD Regulator
  D7D53_RS09110 (D7D53_09110) comE 1800255..1801007 (+) 753 WP_033682534.1 competence system response regulator transcription factor ComE Regulator
  D7D53_RS09125 (D7D53_09125) - 1801250..1801792 (-) 543 WP_049552685.1 TetR/AcrR family transcriptional regulator -
  D7D53_RS09130 (D7D53_09130) - 1801920..1804562 (+) 2643 WP_120770762.1 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52240.38 Da        Isoelectric Point: 6.9102

>NTDB_id=317229 D7D53_RS09105 WP_120770761.1 1798909..1800258(+) (comD/comD2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MGTIVEIILGIIDMLLTCILISMIYGKICKTSNKDKNILGFILLFFQIIYFYFLFMFNNIDLLLIIHYVLINVYPIIFYI
FLKFFKKYNYSKSIFLSILFSLLYQSTHTFLSVISSSITGDLLVQQYEQAFFFIINLISYFIIDKIITYFNLELNYFDKD
YLYPFLKKVFFALLLLHIVSFISDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKEQMEKEIALKQKKFEQKHLQNY
TDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVY
ARNNGVEFTLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=317229 D7D53_RS09105 WP_120770761.1 1798909..1800258(+) (comD/comD2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGGGTACAATAGTTGAAATAATACTAGGAATAATAGATATGTTATTAACTTGCATTTTAATTAGTATGATTTATGGTAA
AATATGCAAAACATCTAATAAAGATAAAAATATTTTAGGTTTTATACTCTTATTTTTTCAAATAATTTATTTTTATTTCT
TATTTATGTTCAATAACATTGATTTATTATTAATTATACATTATGTATTAATTAATGTTTACCCAATTATTTTTTATATT
TTTTTAAAATTTTTCAAAAAATATAATTATTCCAAAAGTATCTTTTTAAGTATATTATTTTCATTACTGTATCAAAGTAC
TCATACTTTTTTATCTGTCATTTCATCATCTATTACAGGAGATTTACTTGTACAACAATATGAACAAGCATTCTTTTTCA
TAATAAATTTAATCTCATATTTTATAATAGATAAAATCATTACATATTTTAATTTGGAACTAAACTATTTTGACAAAGAT
TATCTCTATCCTTTCTTGAAAAAAGTCTTTTTTGCTTTACTACTTCTACATATTGTATCTTTCATTTCAGATATGGTAAG
TACGATTAAACATTTGAATAGTTTTGGAAGTATTTTATCATCTATTGTTTTTATCTCGTTACTTTTGACCTTCTTTGCAA
TGAATTCGCATAAAGAACAAATGGAGAAAGAGATTGCTTTGAAGCAGAAGAAATTCGAACAGAAACATTTACAGAATTAT
ACAGATGAAATTGTTGGCTTGTATAATGAAATCCGTGGTTTTAGACATGACTATGCTGGGATGCTTGTCAGCATGCAGAT
GGCAATTGACAGTGGTGATTTACAGGAAATTGACAGAGTTTACAATGAAGTTTTGGTTAAAGCTAATCACAAACTGCGTT
CAGATAAGTATACTTACTTTGATTTGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTTTAT
GCTCGAAATAATGGTGTAGAGTTTACACTGGAAGTAAAAGATACGATTACTAAGCTCCCAATTGAACTATTGGATTTGGT
TCGTATCATGAGCGTTTTATTGAACAATGCTGTCGAAGGATCGGCTGATAGTTATAAAAAGCAGATGGAAGTAGCAGTTA
TTAAGATGGAAACTGAAACAGTTATTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCT
TTAGGATTCTCCACTAAGGGAAGAAATCGCGGAGTAGGATTAAATAATGTGAAAGAACTATTAGATAAGTACAATAATAT
TATTTTAGAAACAGAGATGGAAGGCAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(342-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus pneumoniae TIGR4

78.076

99.555

0.777
  comD Streptococcus mitis NCTC 12261

78.378

98.886

0.775
  comD/comD1 Streptococcus pneumoniae D39

77.703

98.886

0.768
  comD/comD1 Streptococcus pneumoniae R6

77.703

98.886

0.768
  comD/comD1 Streptococcus pneumoniae Rx1

77.703

98.886

0.768
  comD Streptococcus mitis SK321

76.577

98.886

0.757
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50.521

85.523

0.432
  comD/comD2 Streptococcus gordonii strain NCTC7865

50.131

85.301

0.428

Multiple sequence alignment