Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   D7D53_RS09100 Genome accession   NZ_CP032621
Coordinates   1798770..1798892 (+) Length   40 a.a.
NCBI ID   WP_120770760.1    Uniprot ID   A0A387AZH7
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1793770..1803892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS09075 (D7D53_09075) dnaA 1794252..1795613 (-) 1362 WP_120770756.1 chromosomal replication initiator protein DnaA -
  D7D53_RS09080 (D7D53_09080) spo0J 1795826..1796584 (-) 759 WP_120770757.1 ParB/RepB/Spo0J family partition protein Regulator
  D7D53_RS09085 (D7D53_09085) htrA 1796642..1797823 (-) 1182 WP_120770758.1 S1C family serine protease Regulator
  D7D53_RS09090 (D7D53_09090) rlmH 1798007..1798486 (+) 480 WP_120770759.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  D7D53_RS09100 (D7D53_09100) comC/comC2 1798770..1798892 (+) 123 WP_120770760.1 competence-stimulating peptide ComC Regulator
  D7D53_RS09105 (D7D53_09105) comD/comD2 1798909..1800258 (+) 1350 WP_120770761.1 competence system sensor histidine kinase ComD Regulator
  D7D53_RS09110 (D7D53_09110) comE 1800255..1801007 (+) 753 WP_033682534.1 competence system response regulator transcription factor ComE Regulator
  D7D53_RS09125 (D7D53_09125) - 1801250..1801792 (-) 543 WP_049552685.1 TetR/AcrR family transcriptional regulator -

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4703.61 Da        Isoelectric Point: 11.0075

>NTDB_id=317228 D7D53_RS09100 WP_120770760.1 1798770..1798892(+) (comC/comC2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MKNTVKLEQFVALKEKDLQKIQGGDVRKTFGSFVFLFKKR

Nucleotide


Download         Length: 123 bp        

>NTDB_id=317228 D7D53_RS09100 WP_120770760.1 1798770..1798892(+) (comC/comC2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCTTTGAAGGAAAAAGACTTGCAAAAGATTCAAGGTGGGGATGTTCG
AAAAACTTTTGGTTCTTTCGTATTTCTATTTAAAAAAAGATAA

Domains


Predicted by InterproScan.

(1-27)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A387AZH7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC1 Streptococcus pneumoniae D39

70.732

100

0.725

  comC/comC2 Streptococcus pneumoniae A66

70.732

100

0.725

  comC/comC2 Streptococcus pneumoniae TIGR4

70.732

100

0.725

  comC/comC1 Streptococcus pneumoniae Rx1

70.732

100

0.725

  comC/comC1 Streptococcus pneumoniae R6

70.732

100

0.725

  comC/comC1 Streptococcus pneumoniae G54

70.732

100

0.725

  comC Streptococcus mitis SK321

67.5

100

0.675

  comC Streptococcus mitis NCTC 12261

62.5

100

0.625

  comC Streptococcus sinensis strain Forsyth1A

50

85

0.425


Multiple sequence alignment