Detailed information NTG0306380

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DK878_RS00745
• Genome accession: NZ_CP031379
• Coordinates: 118441..118722 (+)
• Length: 93 a.a.
• NCBI ID: WP_009909092.1
• Uniprot ID: A0A116MYU4
• Organism: Streptococcus suis strain ISU2660
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113441..123722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK878_RS00725 (DK878_00750)	-	115104..115469 (+)	366	WP_002936568.1	DUF1033 family protein	-
DK878_RS00730 (DK878_00755)	-	115504..116454 (-)	951	WP_002936565.1	S66 peptidase family protein	-
DK878_RS00735 (DK878_00760)	comYA	116540..117490 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
DK878_RS00740 (DK878_00765)	comYB	117402..118439 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK878_RS00745 (DK878_00770)	comYC	118441..118722 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
DK878_RS00750 (DK878_00775)	comGD	118703..119110 (+)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
DK878_RS00755 (DK878_00780)	comYE	119082..119375 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK878_RS00760 (DK878_00785)	comGF/cglF	119362..119796 (+)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK878_RS00765 (DK878_00790)	comGG	119774..120184 (+)	411	WP_053866091.1	competence type IV pilus minor pilin ComGG	-
DK878_RS00770 (DK878_00795)	comYH	120241..121194 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
DK878_RS00775 (DK878_00800)	-	121244..122431 (+)	1188	WP_044760379.1	acetate kinase	-
DK878_RS00780 (DK878_00810)	-	122746..123342 (+)	597	WP_009909104.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10320.28 Da
• Isoelectric Point: 8.4284

>NTDB_id=306380 DK878_RS00745 WP_009909092.1 118441..118722(+) (comYC) [Streptococcus suis strain ISU2660]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAAAKK

Nucleotide

• Length: 282 bp

>NTDB_id=306380 DK878_RS00745 WP_009909092.1 118441..118722(+) (comYC) [Streptococcus suis strain ISU2660]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTGCGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A116MYU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	62.637	97.849	0.613
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398