Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DK237_RS00775 Genome accession   NZ_CP031377
Coordinates   122596..123546 (+) Length   316 a.a.
NCBI ID   WP_053861401.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2614     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117596..128546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS00765 (DK237_00785) - 121160..121525 (+) 366 WP_002936568.1 DUF1033 family protein -
  DK237_RS00770 (DK237_00790) - 121560..122510 (-) 951 WP_002936565.1 S66 peptidase family protein -
  DK237_RS00775 (DK237_00795) comYA 122596..123546 (+) 951 WP_053861401.1 competence type IV pilus ATPase ComGA Machinery gene
  DK237_RS00780 (DK237_00800) comYB 123458..124495 (+) 1038 WP_043032925.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK237_RS00785 (DK237_00805) comYC 124497..124778 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  DK237_RS00790 (DK237_00810) comGD 124759..125166 (+) 408 WP_024394702.1 competence type IV pilus minor pilin ComGD -
  DK237_RS00795 (DK237_00815) comYE 125138..125431 (+) 294 WP_024394703.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK237_RS00800 (DK237_00820) comGF/cglF 125418..125852 (+) 435 WP_029750050.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK237_RS00805 (DK237_00825) comGG 125830..126240 (+) 411 WP_024394705.1 competence type IV pilus minor pilin ComGG -
  DK237_RS00810 (DK237_00830) comYH 126297..127250 (+) 954 WP_024394706.1 class I SAM-dependent methyltransferase Machinery gene
  DK237_RS00815 (DK237_00835) - 127300..128487 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35449.29 Da        Isoelectric Point: 5.6997

>NTDB_id=306323 DK237_RS00775 WP_053861401.1 122596..123546(+) (comYA) [Streptococcus suis strain ISU2614]
MIQEKARKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=306323 DK237_RS00775 WP_053861401.1 122596..123546(+) (comYA) [Streptococcus suis strain ISU2614]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTGATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGATATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACGG
CGCGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGCCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.484

98.101

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.259

100

0.544
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment