Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DK237_RS00780 Genome accession   NZ_CP031377
Coordinates   123458..124495 (+) Length   345 a.a.
NCBI ID   WP_043032925.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2614     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 118458..129495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS00765 (DK237_00785) - 121160..121525 (+) 366 WP_002936568.1 DUF1033 family protein -
  DK237_RS00770 (DK237_00790) - 121560..122510 (-) 951 WP_002936565.1 S66 peptidase family protein -
  DK237_RS00775 (DK237_00795) comYA 122596..123546 (+) 951 WP_053861401.1 competence type IV pilus ATPase ComGA Machinery gene
  DK237_RS00780 (DK237_00800) comYB 123458..124495 (+) 1038 WP_043032925.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK237_RS00785 (DK237_00805) comYC 124497..124778 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  DK237_RS00790 (DK237_00810) comGD 124759..125166 (+) 408 WP_024394702.1 competence type IV pilus minor pilin ComGD -
  DK237_RS00795 (DK237_00815) comYE 125138..125431 (+) 294 WP_024394703.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK237_RS00800 (DK237_00820) comGF/cglF 125418..125852 (+) 435 WP_029750050.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK237_RS00805 (DK237_00825) comGG 125830..126240 (+) 411 WP_024394705.1 competence type IV pilus minor pilin ComGG -
  DK237_RS00810 (DK237_00830) comYH 126297..127250 (+) 954 WP_024394706.1 class I SAM-dependent methyltransferase Machinery gene
  DK237_RS00815 (DK237_00835) - 127300..128487 (+) 1188 WP_014637319.1 acetate kinase -
  DK237_RS00820 (DK237_00840) - 128802..129353 (+) 552 WP_014636756.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38886.78 Da        Isoelectric Point: 9.0934

>NTDB_id=306324 DK237_RS00780 WP_043032925.1 123458..124495(+) (comYB) [Streptococcus suis strain ISU2614]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=306324 DK237_RS00780 WP_043032925.1 123458..124495(+) (comYB) [Streptococcus suis strain ISU2614]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAACTGTTTAATAATCTCTTTGCCAGTGGTTTTCATCTGGGAGAGATTGTCGATTTTCTTAAGC
GTAGTCAGCTTTTGGCAGACCCATATACACAAGTTTTATCCGATGGTCTTCTTGCAGGCAAACCTTTTTCAAGTTTGCTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAGGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTTAGCAAGGTTCGTAAAAAATTGATTGAGGTGGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGTAATGCAGCGACAGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comYB Streptococcus mutans UA159

58.892

99.42

0.586
  comYB Streptococcus mutans UA140

58.892

99.42

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496

Multiple sequence alignment