Detailed information NTG0301121

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ETT70_RS07540
• Genome accession: NZ_CP035429
• Coordinates: 1451292..1454120 (-)
• Length: 942 a.a.
• NCBI ID: WP_032465207.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emmNA
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1446292..1459120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT70_RS07510 (ETT70_07500)	-	1446968..1447933 (+)	966	WP_014635676.1	LacI family DNA-binding transcriptional regulator	-
ETT70_RS07515 (ETT70_07505)	nusB	1448074..1448526 (-)	453	WP_002988501.1	transcription antitermination factor NusB	-
ETT70_RS07520 (ETT70_07510)	-	1448519..1448908 (-)	390	WP_002993228.1	Asp23/Gls24 family envelope stress response protein	-
ETT70_RS07525 (ETT70_07515)	efp	1448954..1449511 (-)	558	WP_002988496.1	elongation factor P	-
ETT70_RS07530 (ETT70_07520)	-	1449607..1450068 (-)	462	WP_002988493.1	deaminase	-
ETT70_RS07535 (ETT70_07525)	-	1450103..1451176 (-)	1074	WP_136129636.1	Xaa-Pro peptidase family protein	-
ETT70_RS07540 (ETT70_07530)	uvrA	1451292..1454120 (-)	2829	WP_032465207.1	excinuclease ABC subunit UvrA	Machinery gene
ETT70_RS07545 (ETT70_07535)	-	1454323..1455267 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
ETT70_RS07550 (ETT70_07540)	-	1455399..1456055 (+)	657	WP_002983144.1	DUF1129 domain-containing protein	-
ETT70_RS07555 (ETT70_07545)	rpsR	1456188..1456427 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
ETT70_RS07560 (ETT70_07550)	ssb	1456592..1457083 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
ETT70_RS07565 (ETT70_07555)	rpsF	1457105..1457395 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
ETT70_RS07570 (ETT70_07560)	-	1457568..1457861 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104062.23 Da
• Isoelectric Point: 6.0690

>NTDB_id=301121 ETT70_RS07540 WP_032465207.1 1451292..1454120(-) (uvrA) [Streptococcus pyogenes strain emmNA]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=301121 ETT70_RS07540 WP_032465207.1 1451292..1454120(-) (uvrA) [Streptococcus pyogenes strain emmNA]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGACCAAAAAACCACCAGTAAGAACCCTCGCTCAACGGTTGGTACGGTTACGGAAATCAATGA
TTATTTACGTCTACTATATGCGCGTGTGGGCACACCTTACTGTATCAATGGGCATGGTGCTATCACGGCGTCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGACGGCTATGTCCGTGTGCGCGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCAGAGTTGTCCAAAAGTAAGATGCACAACATTGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGATTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTAACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTACATG
AATGAATTGACTTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCTTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCGACACAGATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCTCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGCAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• UvrA interaction domain (UvrA_inter) (132-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.926	100	0.849
uvrA	Streptococcus pneumoniae TIGR4	84.926	100	0.849
uvrA	Streptococcus pneumoniae D39	84.926	100	0.849