Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DP112_RS00795 Genome accession   NZ_CP030125
Coordinates   124576..125526 (+) Length   316 a.a.
NCBI ID   WP_105149231.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 119576..130526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS00785 (DP112_00785) - 123138..123512 (+) 375 WP_024385120.1 DUF1033 family protein -
  DP112_RS00790 (DP112_00790) - 123540..124490 (-) 951 WP_105134139.1 S66 peptidase family protein -
  DP112_RS00795 (DP112_00795) comYA 124576..125526 (+) 951 WP_105149231.1 competence type IV pilus ATPase ComGA Machinery gene
  DP112_RS00800 (DP112_00800) comYB 125438..126475 (+) 1038 WP_238139242.1 competence type IV pilus assembly protein ComGB Machinery gene
  DP112_RS00805 (DP112_00805) comYC 126477..126758 (+) 282 WP_114866111.1 competence type IV pilus major pilin ComGC Machinery gene
  DP112_RS00810 (DP112_00810) comGD 126739..127146 (+) 408 WP_114866112.1 competence type IV pilus minor pilin ComGD -
  DP112_RS00815 (DP112_00815) comYE 127118..127411 (+) 294 WP_114866113.1 competence type IV pilus minor pilin ComGE Machinery gene
  DP112_RS00820 (DP112_00820) comGF/cglF 127398..127832 (+) 435 WP_024407345.1 competence type IV pilus minor pilin ComGF Machinery gene
  DP112_RS00825 (DP112_00825) comGG 127810..128220 (+) 411 WP_114866114.1 competence type IV pilus minor pilin ComGG -
  DP112_RS00830 (DP112_00830) comYH 128277..129230 (+) 954 WP_114866115.1 class I SAM-dependent methyltransferase Machinery gene
  DP112_RS00835 (DP112_00835) - 129280..130467 (+) 1188 WP_114866116.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35449.31 Da        Isoelectric Point: 5.4746

>NTDB_id=299465 DP112_RS00795 WP_105149231.1 124576..125526(+) (comYA) [Streptococcus suis strain HA1003]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDLAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=299465 DP112_RS00795 WP_105149231.1 124576..125526(+) (comYA) [Streptococcus suis strain HA1003]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGGCTATCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAAGAAGTAATAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGTAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATTGGTGAGATTCGGGATGCGGAAACTG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTTTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCTCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCGAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361

Multiple sequence alignment